Human Amniotic Mesenchymal Stem Cells and Fibroblasts Accelerate Wound Repair of Cystic Fibrosis Epithelium.

airway epithelium cell proliferation cystic fibrosis fibroblasts human mesenchymal stem cells wound repair

Journal

Life (Basel, Switzerland)
ISSN: 2075-1729
Titre abrégé: Life (Basel)
Pays: Switzerland
ID NLM: 101580444

Informations de publication

Date de publication:
19 May 2022
Historique:
received: 21 04 2022
revised: 12 05 2022
accepted: 16 05 2022
entrez: 28 5 2022
pubmed: 29 5 2022
medline: 29 5 2022
Statut: epublish

Résumé

Cystic fibrosis (CF) airways are affected by a deranged repair of the damaged epithelium resulting in altered regeneration and differentiation. Previously, we showed that human amniotic mesenchymal stem cells (hAMSCs) corrected base defects of CF airway epithelial cells via connexin (CX)43-intercellular gap junction formation. In this scenario, it is unknown whether hAMSCs, or fibroblasts sharing some common characteristics with MSCs, can operate a faster repair of a damaged airway epithelium. A tip-based scratch assay was employed to study wound repair in monolayers of CFBE14o- cells (CFBE, homozygous for the

Identifiants

pubmed: 35629422
pii: life12050756
doi: 10.3390/life12050756
pmc: PMC9144497
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : University of Foggia
ID : DR n. 392-2019, Prot. N. 13546- VII/1, 01/04/2019

Références

Stem Cells Int. 2018 Jan 11;2018:1203717
pubmed: 29531530
J Physiol Pharmacol. 2008 Dec;59 Suppl 6:565-72
pubmed: 19218682
J Submicrosc Cytol Pathol. 1989 Jul;21(3):521-34
pubmed: 2790733
Expert Opin Biol Ther. 2018 Mar;18(3):281-292
pubmed: 29216777
Cell. 1993 Jul 2;73(7):1251-4
pubmed: 7686820
Cell Mol Life Sci. 2015 Aug;72(15):2775-8
pubmed: 26084871
Am J Physiol Lung Cell Mol Physiol. 2011 Dec;301(6):L945-55
pubmed: 21908587
Pathophysiology. 2021 Mar 10;28(1):155-188
pubmed: 35366275
J Biomed Biotechnol. 2012;2012:575471
pubmed: 22315512
Front Mol Biosci. 2022 Mar 09;9:850261
pubmed: 35372502
J Cell Sci. 2003 Aug 15;116(Pt 16):3443-52
pubmed: 12840073
Am J Physiol Cell Physiol. 2010 Nov;299(5):C912-21
pubmed: 20686068
Life Sci Alliance. 2022 May 2;5(9):
pubmed: 35500936
Int J Mol Sci. 2020 Sep 14;21(18):
pubmed: 32937756
J Wound Care. 2016 Jan;25(1):46-55
pubmed: 26762498
J Cell Biol. 1995 Jul;130(2):419-29
pubmed: 7542247
Thorax. 2018 Jan;73(1):49-61
pubmed: 28790180
Int J Mol Sci. 2022 Feb 28;23(5):
pubmed: 35269829
Molecules. 2021 Feb 09;26(4):
pubmed: 33572331
Stem Cell Res Ther. 2020 Apr 3;11(1):146
pubmed: 32245507
Front Physiol. 2016 Dec 06;7:596
pubmed: 27999549
J Cyst Fibros. 2004 Aug;3 Suppl 2:191-6
pubmed: 15463957
Stem Cells Int. 2016;2016:5303048
pubmed: 26925108
J Cyst Fibros. 2018 Nov;17(6):705-714
pubmed: 29661510
J Cell Sci. 2016 Dec 1;129(23):4399-4410
pubmed: 27777264
Am J Respir Crit Care Med. 2005 Oct 15;172(8):1013-8
pubmed: 16020799
J Pathol. 2005 Jun;206(2):160-9
pubmed: 15806599
Int J Mol Sci. 2018 Feb 18;19(2):
pubmed: 29463027
Am J Respir Crit Care Med. 1998 Aug;158(2):580-8
pubmed: 9700138
Eur Respir J. 2000 Apr;15(4):735-42
pubmed: 10780767
Eur Respir J. 2012 Dec;40(6):1390-400
pubmed: 22496330
J Cell Physiol. 2018 Dec;233(12):9099-9109
pubmed: 29943820
Am J Respir Cell Mol Biol. 1995 Jun;12(6):605-12
pubmed: 7766425
PLoS One. 2017 Apr 18;12(4):e0175986
pubmed: 28419140
Mol Ther. 2009 Jul;17(7):1257-65
pubmed: 19417738
J Cell Biol. 1995 May;129(3):805-17
pubmed: 7537274
J Stem Cell Res Ther. 2017 Aug;7(9):
pubmed: 29291140
Int J Mol Sci. 2020 Apr 29;21(9):
pubmed: 32365523
Am J Physiol Cell Physiol. 2014 May 1;306(9):C819-30
pubmed: 24500283
Cell Signal. 2018 Nov;51:110-118
pubmed: 30076968
FASEB J. 2016 Sep;30(9):3011-25
pubmed: 27178322
Int J Mol Sci. 2018 May 03;19(5):
pubmed: 29751558
Cell. 1998 Dec 23;95(7):1005-15
pubmed: 9875854
Nature. 2018 Sep;561(7721):45-56
pubmed: 30185958
Lancet. 2021 Jun 5;397(10290):2195-2211
pubmed: 34090606
J Pathol. 2015 Feb;235(3):408-19
pubmed: 25348090
Cell Death Dis. 2020 Oct 26;11(10):920
pubmed: 33106471
Biochim Biophys Acta. 2005 Jun 10;1711(2):197-207
pubmed: 15955304
J Cell Mol Med. 2014 Aug;18(8):1631-43
pubmed: 24894806
Biol Cell. 2011 Apr;103(4):197-208
pubmed: 21332447
Mol Biol Cell. 1995 Nov;6(11):1491-501
pubmed: 8589451
Front Pharmacol. 2019 Feb 08;10:74
pubmed: 30800069
Cell Tissue Res. 2015 Jun;360(3):685-99
pubmed: 25547217
Lab Invest. 2000 Feb;80(2):209-19
pubmed: 10701690
Cancer Res. 1995 Feb 1;55(3):629-39
pubmed: 7834634
Semin Immunol. 2018 Feb;35:48-58
pubmed: 29198601
Acta Histochem. 2020 Dec;122(8):151634
pubmed: 33059115
Am J Physiol Lung Cell Mol Physiol. 2010 Jun;298(6):L715-31
pubmed: 20363851
J Transl Med. 2018 Jul 27;16(1):212
pubmed: 30053821
Int J Biochem Cell Biol. 2014 Jul;52:152-60
pubmed: 24569117
Clin Exp Immunol. 2001 Apr;124(1):69-76
pubmed: 11359444
Sci Data. 2019 Oct 29;6(1):240
pubmed: 31664037
Plast Reconstr Surg. 2016 Sep;138(3 Suppl):18S-28S
pubmed: 27556760
Am J Physiol Lung Cell Mol Physiol. 2008 Nov;295(5):L866-80
pubmed: 18757521
J Pathol. 2007 Feb;211(3):340-50
pubmed: 17186573

Auteurs

Elisa Beccia (E)

Department of Clinical and Experimental Medicine, University of Foggia, 71122 Foggia, Italy.
Department of Medicine and Health Sciences "V. Tiberio", University of Molise, 86100 Campobasso, Italy.

Valeria Daniello (V)

Department of Clinical and Experimental Medicine, University of Foggia, 71122 Foggia, Italy.

Onofrio Laselva (O)

Department of Clinical and Experimental Medicine, University of Foggia, 71122 Foggia, Italy.

Giorgia Leccese (G)

Department of Clinical and Experimental Medicine, University of Foggia, 71122 Foggia, Italy.

Michele Mangiacotti (M)

S.C. di Radioterapia Oncologica, Policlinico Riuniti, Azienda Ospedaliero-Universitaria, 71122 Foggia, Italy.

Sante Di Gioia (S)

Department of Clinical and Experimental Medicine, University of Foggia, 71122 Foggia, Italy.

Gianfranco La Bella (G)

Istituto Zooprofilattico Sperimentale della Puglia e della Basilicata (IZSPB), 71121 Foggia, Italy.

Lorenzo Guerra (L)

Department of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari, 70125 Bari, Italy.

Maria Matteo (M)

Department of Medical and Surgical Sciences, University of Foggia, 71122 Foggia, Italy.

Antonella Angiolillo (A)

Department of Medicine and Health Sciences "V. Tiberio", University of Molise, 86100 Campobasso, Italy.

Massimo Conese (M)

Department of Clinical and Experimental Medicine, University of Foggia, 71122 Foggia, Italy.

Classifications MeSH