The Role of Cryotherapy in Vitreous Concentrations of Topotecan Delivered by Episcleral Hydrogel Implant.

HEMA episcleral implant hydrogel intraocular delivery periocular delivery retina retinoblastoma topotecan transconjunctival cryotherapy transscleral diffusion

Journal

Pharmaceutics
ISSN: 1999-4923
Titre abrégé: Pharmaceutics
Pays: Switzerland
ID NLM: 101534003

Informations de publication

Date de publication:
20 Apr 2022
Historique:
received: 28 02 2022
revised: 13 04 2022
accepted: 18 04 2022
entrez: 28 5 2022
pubmed: 29 5 2022
medline: 29 5 2022
Statut: epublish

Résumé

Transscleral diffusion delivery of chemotherapy is a promising way to reach the vitreal seeds of retinoblastoma, the most common intraocular malignancy in childhood. In this

Identifiants

pubmed: 35631489
pii: pharmaceutics14050903
doi: 10.3390/pharmaceutics14050903
pmc: PMC9144907
pii:
doi:

Types de publication

Journal Article

Langues

eng

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Auteurs

Martina Kodetova (M)

Department of Ophthalmology, 2nd Faculty of Medicine, Charles University and Motol University Hospital, 150 06 Prague, Czech Republic.

Radka Hobzova (R)

Institute of Macromolecular Chemistry, Academy of Sciences of the Czech Republic, 162 06 Prague, Czech Republic.

Jakub Sirc (J)

Institute of Macromolecular Chemistry, Academy of Sciences of the Czech Republic, 162 06 Prague, Czech Republic.

Jiri Uhlik (J)

Department of Histology and Embryology, 2nd Faculty of Medicine, Charles University, 150 06 Prague, Czech Republic.

Katerina Dunovska (K)

Department of Medical Chemistry and Clinical Biochemistry, 2nd Faculty of Medicine, Charles University and Motol University Hospital, 150 06 Prague, Czech Republic.

Karel Svojgr (K)

Department of Pediatric Hematology and Oncology, 2nd Faculty of Medicine, Charles University and Motol University Hospital, 150 06 Prague, Czech Republic.

Ana-Irina Cocarta (AI)

Institute of Macromolecular Chemistry, Academy of Sciences of the Czech Republic, 162 06 Prague, Czech Republic.

Andrea Felsoova (A)

Department of Histology and Embryology, 2nd Faculty of Medicine, Charles University, 150 06 Prague, Czech Republic.
Clinical and Transplant Pathology Centre, Institute for Clinical and Experimental Medicine, 140 21 Prague, Czech Republic.

Ondrej Slanar (O)

Department of Pharmacology, First Faculty of Medicine, Charles University and General University Hospital in Prague, 128 00 Prague, Czech Republic.

Martin Sima (M)

Department of Pharmacology, First Faculty of Medicine, Charles University and General University Hospital in Prague, 128 00 Prague, Czech Republic.

Igor Kozak (I)

Moorfields Eye Hospital, Abu Dhabi P.O. Box 62807, United Arab Emirates.

Pavel Pochop (P)

Department of Ophthalmology, 2nd Faculty of Medicine, Charles University and Motol University Hospital, 150 06 Prague, Czech Republic.

Classifications MeSH