Severity of early diagnosed organ/space surgical site infection in elective gastrointestinal and hepatopancreatobiliary surgery.
abdominal abscess
anastomotic leak
digestive system surgical procedures
pancreatic fistula
surgical wound infection
Journal
Annals of gastroenterological surgery
ISSN: 2475-0328
Titre abrégé: Ann Gastroenterol Surg
Pays: Japan
ID NLM: 101718062
Informations de publication
Date de publication:
May 2022
May 2022
Historique:
received:
27
10
2021
revised:
22
11
2021
accepted:
09
12
2021
entrez:
31
5
2022
pubmed:
1
6
2022
medline:
1
6
2022
Statut:
epublish
Résumé
Organ/space surgical site infection (SSI) is a significant clinical problem. The postdiagnosis course of organ/space SSIs and the impact of its early diagnosis on clinical outcomes are yet to be clarified. Thus, we aimed to investigate the association between the timing of diagnosis and the clinical outcome of organ/space SSI. This retrospective, single-center cohort study evaluated patients who underwent elective gastrointestinal or hepatopancreatobiliary surgery between 2016 and 2020. Clinical outcomes were compared between the early group (ie, SSI diagnosed until postoperative day [POD] 4) and normal-late group (ie, SSI diagnosed after POD 5). The primary outcome was the final C-reactive protein (CRP) level within 14 d after organ/space SSI diagnosis. In total, 110 patients were evaluated. The median time of diagnosis was 7 d postoperatively (interquartile range, 5-9 d postoperatively). Compared with the normal-late group, the early group included a higher proportion of patients with Clavien-Dindo grade ≥IIIb (8/21 vs 11/89, Early diagnosed organ/space SSI are originally severe and may therefore be detected earlier. Importantly, early diagnosed organ/space SSI is likely to be severe and refractory.
Sections du résumé
Background
UNASSIGNED
Organ/space surgical site infection (SSI) is a significant clinical problem. The postdiagnosis course of organ/space SSIs and the impact of its early diagnosis on clinical outcomes are yet to be clarified. Thus, we aimed to investigate the association between the timing of diagnosis and the clinical outcome of organ/space SSI.
Methods
UNASSIGNED
This retrospective, single-center cohort study evaluated patients who underwent elective gastrointestinal or hepatopancreatobiliary surgery between 2016 and 2020. Clinical outcomes were compared between the early group (ie, SSI diagnosed until postoperative day [POD] 4) and normal-late group (ie, SSI diagnosed after POD 5). The primary outcome was the final C-reactive protein (CRP) level within 14 d after organ/space SSI diagnosis.
Results
UNASSIGNED
In total, 110 patients were evaluated. The median time of diagnosis was 7 d postoperatively (interquartile range, 5-9 d postoperatively). Compared with the normal-late group, the early group included a higher proportion of patients with Clavien-Dindo grade ≥IIIb (8/21 vs 11/89,
Conclusion
UNASSIGNED
Early diagnosed organ/space SSI are originally severe and may therefore be detected earlier. Importantly, early diagnosed organ/space SSI is likely to be severe and refractory.
Identifiants
pubmed: 35634192
doi: 10.1002/ags3.12539
pii: AGS312539
pmc: PMC9130879
doi:
Types de publication
Journal Article
Langues
eng
Pagination
445-453Informations de copyright
© 2021 The Authors. Annals of Gastroenterological Surgery published by John Wiley & Sons Australia, Ltd on behalf of The Japanese Society of Gastroenterology.
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