Stable and direct coating of fibronectin-derived Leu-Asp-Val peptide on ePTFE using one-pot tyrosine oxidation for endothelial cell adhesion.
Endothelial cell adhesion
Leu-Asp-Val (LDV)
One-pot tyrosine oxidation
Peptide coating
ePTFE
Journal
Colloids and surfaces. B, Biointerfaces
ISSN: 1873-4367
Titre abrégé: Colloids Surf B Biointerfaces
Pays: Netherlands
ID NLM: 9315133
Informations de publication
Date de publication:
Aug 2022
Aug 2022
Historique:
received:
21
03
2022
revised:
30
04
2022
accepted:
11
05
2022
pubmed:
1
6
2022
medline:
22
6
2022
entrez:
31
5
2022
Statut:
ppublish
Résumé
Expanded polytetrafluoroethylene (ePTFE) is widely used in clinical applications, such as in the manufacture of blood-contacting implantable devices, owing to its flexibility, biostability, and non-adhesiveness. Modification with peptides is an effective strategy to further improve the ePTFE function. However, the chemical stability of PTFE makes it difficult to modify with peptides. In this study, we reported a simple method for the dense and stable coating of biofunctional peptides on the ePTFE surface through the anchor sequence, Tyr-Lys-Tyr-Lys-Tyr-Lys (YK3). A peptide (YK3-LDV) incorporating the YK3 anchor and a ligand sequence for α
Identifiants
pubmed: 35636324
pii: S0927-7765(22)00259-4
doi: 10.1016/j.colsurfb.2022.112576
pii:
doi:
Substances chimiques
Fibronectins
0
Oligopeptides
0
Peptides
0
leucyl-aspartyl-valine
125850-12-6
Tyrosine
42HK56048U
Polytetrafluoroethylene
9002-84-0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
112576Informations de copyright
Copyright © 2022 Elsevier B.V. All rights reserved.