Changes in (poly)phenols intake and metabolic syndrome risk over ten years from adolescence to adulthood.


Journal

Nutrition, metabolism, and cardiovascular diseases : NMCD
ISSN: 1590-3729
Titre abrégé: Nutr Metab Cardiovasc Dis
Pays: Netherlands
ID NLM: 9111474

Informations de publication

Date de publication:
08 2022
Historique:
received: 12 08 2021
revised: 17 04 2022
accepted: 19 04 2022
pubmed: 1 6 2022
medline: 20 7 2022
entrez: 31 5 2022
Statut: ppublish

Résumé

(Poly)phenols might contribute to prevent cardiovascular disease, but limited prospective studies exist among adolescents. This study aimed to evaluate within-subject longitudinal changes in (poly)phenols intakes and food group contributors while also exploring the association with metabolic syndrome risk (MetS) during 10 years of follow up in European adolescents becoming young adults. In 164 participants (58% girls, 13-18 y at baseline) from Ghent, Zaragoza and Lille, longitudinal data (2006-2016) on (poly)phenol intake was retrieved via 2 or 3 24 h recalls. Linear and logistic longitudinal regression tested the association of (poly)phenols intake (total and classes) with Mets risk or its components (waist-height-ratio, HDL cholesterol, LDL cholesterol, triglycerides, blood pressure and insulin resistance index), adjusted for age, sex, country and other nutrient intakes. The total (poly)phenols intake was 421 ± 107 mg/day (192 mg/1000 kcal/day) at baseline, while 610 ± 101 mg/day (311 mg/1000 kcal/day) at follow-up. The three major food sources for (poly)phenols were 'chocolate', 'fruit and vegetable juices', 'cakes and biscuits' during adolescence and 'coffee', 'tea' and 'chocolate' during adulthood. Phenolic acid intake was associated with less LDL increase over time, while stilbene intake with a steeper increase in triglycerides over time. Differences in major (poly)phenols contributors over time were partially explained by age-specific dietary changes like increased coffee and tea during adulthood. Some significant (poly)phenols-MetS associations might argue for nutrition-based disease prevention during adolescence, especially since adolescents had low (poly)phenols intake.

Sections du résumé

BACKGROUND AND AIMS
(Poly)phenols might contribute to prevent cardiovascular disease, but limited prospective studies exist among adolescents. This study aimed to evaluate within-subject longitudinal changes in (poly)phenols intakes and food group contributors while also exploring the association with metabolic syndrome risk (MetS) during 10 years of follow up in European adolescents becoming young adults.
METHODS AND RESULTS
In 164 participants (58% girls, 13-18 y at baseline) from Ghent, Zaragoza and Lille, longitudinal data (2006-2016) on (poly)phenol intake was retrieved via 2 or 3 24 h recalls. Linear and logistic longitudinal regression tested the association of (poly)phenols intake (total and classes) with Mets risk or its components (waist-height-ratio, HDL cholesterol, LDL cholesterol, triglycerides, blood pressure and insulin resistance index), adjusted for age, sex, country and other nutrient intakes. The total (poly)phenols intake was 421 ± 107 mg/day (192 mg/1000 kcal/day) at baseline, while 610 ± 101 mg/day (311 mg/1000 kcal/day) at follow-up. The three major food sources for (poly)phenols were 'chocolate', 'fruit and vegetable juices', 'cakes and biscuits' during adolescence and 'coffee', 'tea' and 'chocolate' during adulthood. Phenolic acid intake was associated with less LDL increase over time, while stilbene intake with a steeper increase in triglycerides over time.
CONCLUSIONS
Differences in major (poly)phenols contributors over time were partially explained by age-specific dietary changes like increased coffee and tea during adulthood. Some significant (poly)phenols-MetS associations might argue for nutrition-based disease prevention during adolescence, especially since adolescents had low (poly)phenols intake.

Identifiants

pubmed: 35637083
pii: S0939-4753(22)00186-7
doi: 10.1016/j.numecd.2022.04.015
pii:
doi:

Substances chimiques

Phenols 0
Triglycerides 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1830-1840

Informations de copyright

Copyright © 2022 The Italian Diabetes Society, the Italian Society for the Study of Atherosclerosis, the Italian Society of Human Nutrition and the Department of Clinical Medicine and Surgery, Federico II University. Published by Elsevier B.V. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of competing interest The authors declare that they have no conflict of interest. The authors alone are responsible for the views expressed in this article and they do not necessarily represent the views, decisions or policies of the institutions with which they are affiliated.

Auteurs

Ratih W Wisnuwardani (RW)

Department of Public Health and Primary Care, Faculty of Medicine and Health Sciences, Ghent University, C.Heymanslaan 10 - 4K3, 9000 Ghent, Belgium; Departments of Public Health Nutrition, Faculty of Public Health, Mulawarman University, Samarinda, East Kalimantan, Indonesia. Electronic address: ratih@fkm.unmul.ac.id.

Stefaan De Henauw (S)

Department of Public Health and Primary Care, Faculty of Medicine and Health Sciences, Ghent University, C.Heymanslaan 10 - 4K3, 9000 Ghent, Belgium. Electronic address: Stefaan.DeHenauw@UGent.be.

Laurent Béghin (L)

Univ. Lille, Inserm, CHU Lille, CIC 1403 - Centre D'investigation Clinique, F-59000 Lille, France; Univ. Lille, Inserm, CHU Lille, U1286 - INFINITE - Institute for Translational Research in Inflammation, F-59000 Lille, France. Electronic address: Laurent.BEGHIN@CHRU-LILLE.FR.

Maria Isabel Mesana (MI)

GENUD (Growth, Exercise, Nutrition and Development) Research Group, Faculty of Health Science, University of Zaragoza, C/Pedro Cerbuna 12, 50009 Zaragoza, Spain. Electronic address: maribelmesana@gmail.com.

Frédéric Gottrand (F)

Univ. Lille, Inserm, CHU Lille, CIC 1403 - Centre D'investigation Clinique, F-59000 Lille, France; Univ. Lille, Inserm, CHU Lille, U1286 - INFINITE - Institute for Translational Research in Inflammation, F-59000 Lille, France. Electronic address: Frederic.GOTTRAND@chru-lille.fr.

Luis A Moreno (LA)

GENUD (Growth, Exercise, Nutrition and Development) Research Group, Faculty of Health Science, University of Zaragoza, C/Pedro Cerbuna 12, 50009 Zaragoza, Spain; Instituto Agroalimentario de Aragón (IA2) and Instituto de Investigación Sanitaria de Aragón (IIS Aragón), Spain; Centro de Investigación Biomédica en Red de Fisiopatología de La Obesidad y Nutrición (CIBEROBN), Spain; Instituto de Salud Carlos III, Madrid, Spain. Electronic address: lmoreno@unizar.es.

Nathalie Michels (N)

Department of Public Health and Primary Care, Faculty of Medicine and Health Sciences, Ghent University, C.Heymanslaan 10 - 4K3, 9000 Ghent, Belgium. Electronic address: Nathalie.Michels@ugent.be.

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