Comparative Content, Biological and Anticancer Activities of Heracleum humile Extracts Obtained by Ultrasound-Assisted Extraction Method.
Heracleum humile
anticancer
different extracts
enzyme inhibitor
ultrasound-assisted extraction
Journal
Chemistry & biodiversity
ISSN: 1612-1880
Titre abrégé: Chem Biodivers
Pays: Switzerland
ID NLM: 101197449
Informations de publication
Date de publication:
Jul 2022
Jul 2022
Historique:
received:
31
12
2021
accepted:
27
05
2022
pubmed:
1
6
2022
medline:
28
7
2022
entrez:
31
5
2022
Statut:
ppublish
Résumé
As the safety and effectiveness of synthetic drugs remain in doubt, researchers are trying to develop natural medicines from medicinal plants. Herein, ethyl acetate, methanol and water extracts from the Heracleum humile plant were obtained by an ultrasonic-assisted extraction process and the aim was to evaluate some biological effects of the extracts due to the limited data on the pharmacological properties of Heracleum humile in the literature. Weak antibacterial activity was observed on tested bacterial species. The minimum inhibitory concentration and the minimum bactericidal concentration values ranged from 250 to 500 μg/mL. In addition, cytotoxic activity was determined using the MTT test. The strongest findings were determined for ethyl acetate extract on the MDA-MB-231 cell lines at the 48
Identifiants
pubmed: 35638152
doi: 10.1002/cbdv.202101040
doi:
Substances chimiques
Anti-Bacterial Agents
0
Antioxidants
0
Flavonoids
0
Plant Extracts
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e202101040Subventions
Organisme : Kastamonu University Scientific Projects Research Office
ID : KÜ-BAP01/2019-20
Organisme : Kastamonu University Scientific Projects Research Office
ID : KÜ-HIZDES/2019-11
Informations de copyright
© 2022 Wiley-VHCA AG, Zurich, Switzerland.
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