Syntheses of 3-Aryl Tetrahydroisoquinolines via an Intermolecular [4 + 2] Cycloaddition of Sultines with Imines.

Cyclization Cycloaddition Reaction Imines Stereoisomerism Tetrahydroisoquinolines

Journal

Organic letters
ISSN: 1523-7052
Titre abrégé: Org Lett
Pays: United States
ID NLM: 100890393

Informations de publication

Date de publication:
17 06 2022
Historique:
pubmed: 1 6 2022
medline: 22 6 2022
entrez: 31 5 2022
Statut: ppublish

Résumé

The development of an intermolecular aza-Diels-Alder (DA) cycloaddition of sultines and imines is reported. By exploiting sultines as

Identifiants

DOI: 10.1021/acs.orglett.2c01437 PMID: 35639829
pubmed: 35639829
doi: 10.1021/acs.orglett.2c01437
doi:

Substances chimiques

Imines 0
Tetrahydroisoquinolines 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

4192-4196

Auteurs

Aurapat Ngamnithiporn (A)

Laboratory of Medicinal Chemistry, Chulabhorn Research Institute, 54 Kamphaeng Phet 6 Road, Bangkok 10210, Thailand.
ORCID: 0000-0002-5389-8171

Padon Chuentragool (P)

Laboratory of Medicinal Chemistry, Chulabhorn Research Institute, 54 Kamphaeng Phet 6 Road, Bangkok 10210, Thailand.
ORCID: 0000-0002-7466-8455

Poonsakdi Ploypradith (P)

Laboratory of Medicinal Chemistry, Chulabhorn Research Institute, 54 Kamphaeng Phet 6 Road, Bangkok 10210, Thailand.
Program in Chemical Sciences, Chulabhorn Graduate Institute, Chulabhorn Royal Academy, Bangkok 10210, Thailand.
Center of Excellence on Environmental Health and Toxicology, Office of the Permanent Secretary (OPS), Ministry of Higher Education, Science, Research and Innovation (MHESI), Bangkok 10400, Thailand.
ORCID: 0000-0003-2893-1598

Somsak Ruchirawat (S)

Laboratory of Medicinal Chemistry, Chulabhorn Research Institute, 54 Kamphaeng Phet 6 Road, Bangkok 10210, Thailand.
Program in Chemical Sciences, Chulabhorn Graduate Institute, Chulabhorn Royal Academy, Bangkok 10210, Thailand.
Center of Excellence on Environmental Health and Toxicology, Office of the Permanent Secretary (OPS), Ministry of Higher Education, Science, Research and Innovation (MHESI), Bangkok 10400, Thailand.

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Classifications MeSH

questionsmedicales.fr › Métabolisme › Cyclisation › Syntheses of 3-Aryl Tetrahydroisoquinolines...
questionsmedicales.fr › Technologie, industrie et agriculture › Technologie › Technologie pharmaceutique › Techniques de chimie synthétique › Réaction de cycloaddition › Syntheses of 3-Aryl Tetrahydroisoquinolines...
questionsmedicales.fr › Composés chimiques organiques › Imines › Syntheses of 3-Aryl Tetrahydroisoquinolines...
questionsmedicales.fr › Phénomènes chimiques › Phénomènes de chimie organique › Isomérie › Stéréoisomérie › Syntheses of 3-Aryl Tetrahydroisoquinolines...
questionsmedicales.fr › Composés hétérocycliques › Composés hétérocycliques à cycles fusionnés › Composés hétérobicycliques › Isoquinoléines › Tétrahydroisoquinoléines › Syntheses of 3-Aryl Tetrahydroisoquinolines...