First case of endophthalmitis by Corynespora cassiicola.


Journal

Journal de mycologie medicale
ISSN: 1773-0449
Titre abrégé: J Mycol Med
Pays: France
ID NLM: 9425651

Informations de publication

Date de publication:
Nov 2022
Historique:
received: 04 03 2022
revised: 10 05 2022
accepted: 20 05 2022
pubmed: 1 6 2022
medline: 18 11 2022
entrez: 31 5 2022
Statut: ppublish

Résumé

Corynespora cassiicola is an environmental phytopathogen implicated in various human infections and has been isolated from one case of keratitis. We report here the first case of endophthalmitis caused by Corynespora cassiicola in a 54-year-old diabetic patient, who developed diminished vision, redness, and watering in the right eye, six weeks after intravitreal triamcinolone acetonide for non-proliferative diabetic retinopathy and macular oedema. Direct microscopy of the vitreous tap revealed septate hyphae, and culture grew white mycelium that turned olive-grey to black within two days and was confirmed as C. cassiicola after sequencing of the ITS region of 28S rDNA. The patient was started on oral voriconazole 200 mg twice a day. The patient is on regular follow-up without recurrence. To our knowledge, this case represents the first case of endophthalmitis due to this fungus across the globe and the first case of C. cassiicola infection from India.

Identifiants

pubmed: 35640523
pii: S1156-5233(22)00055-5
doi: 10.1016/j.mycmed.2022.101298
pii:
doi:

Substances chimiques

Triamcinolone Acetonide F446C597KA

Types de publication

Case Reports

Langues

eng

Sous-ensembles de citation

IM

Pagination

101298

Informations de copyright

Copyright © 2022 SFMM. Published by Elsevier Masson SAS. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of Competing Interest None.

Auteurs

Parakriti Gupta (P)

Department of Medical Microbiology, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India.

Atul Arora (A)

Advanced Eye Centre, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Mantavya Gupta (M)

Precise Healthcare Clinical Laboratory, Sector 30, Chandigarh.

Ramandeep Singh (R)

Advanced Eye Centre, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Shivaprakash M Rudramurthy (SM)

Department of Medical Microbiology, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India.

Harsimran Kaur (H)

Department of Medical Microbiology, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India. Electronic address: drharsimranpgi@gmail.com.

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Classifications MeSH