Specialized Weaning Unit in the Trajectory of SARS-CoV-2 ARDS: Influence of Limb Muscle Strength on Decannulation and Rehabilitation.


Journal

Respiratory care
ISSN: 1943-3654
Titre abrégé: Respir Care
Pays: United States
ID NLM: 7510357

Informations de publication

Date de publication:
08 2022
Historique:
pubmed: 1 6 2022
medline: 29 7 2022
entrez: 31 5 2022
Statut: ppublish

Résumé

Patients with ARDS due to COVID-19 may require tracheostomy and transfer to a weaning center. To date, data on the outcome of these patients are scarce. The objectives of this study were to determine the factors associated with time to decannulation and limb-muscle strength recovery. This was an observational retrospective study of subjects with COVID-19-related ARDS requiring tracheostomy after prolonged ventilation, who were subsequently transferred to a weaning center from April 4, 2020-May 30, 2020. Forty-three subjects were included. Median age (interquartile range) was 61 (48-66) y; 81% were men, and median body mass index (BMI) was 30 (26-35) kg/m MRC score at weaning center admission predicted both early decannulation and limb-muscle strength recovery.

Sections du résumé

BACKGROUND
Patients with ARDS due to COVID-19 may require tracheostomy and transfer to a weaning center. To date, data on the outcome of these patients are scarce. The objectives of this study were to determine the factors associated with time to decannulation and limb-muscle strength recovery.
METHODS
This was an observational retrospective study of subjects with COVID-19-related ARDS requiring tracheostomy after prolonged ventilation, who were subsequently transferred to a weaning center from April 4, 2020-May 30, 2020.
RESULTS
Forty-three subjects were included. Median age (interquartile range) was 61 (48-66) y; 81% were men, and median body mass index (BMI) was 30 (26-35) kg/m
CONCLUSIONS
MRC score at weaning center admission predicted both early decannulation and limb-muscle strength recovery.

Identifiants

pubmed: 35640998
pii: respcare.09602
doi: 10.4187/respcare.09602
doi:

Types de publication

Journal Article Observational Study

Langues

eng

Sous-ensembles de citation

IM

Pagination

967-975

Informations de copyright

Copyright © 2022 by Daedalus Enterprises.

Déclaration de conflit d'intérêts

Dr Faure discloses relationships GE Medical System, Pfizer, Bayer Healthcare, and Actelion. Dr Decavèle discloses a relationship with Isis Medical. Dr Dres discloses relationships with BioSerenity and Lungpacer. Dr Mayaux discloses a relationship with Gilead. Dr Caliez discloses a relationship with Oxyvie. Dr Similowski discloses relationships with ADEP Assistance, AstraZeneca France, Chiesi France, GlaxoSmithKline France, Lungpacer Canada, Novartis France, and Teva France. Dr Demoule discloses relationships with Philips, Baxter, Fisher & Paykel, French Ministry of Health, Getinge, Respinor, Lungpacer, Lowenstein, and Gilead. The remaining authors have disclosed no conflicts of interest.

Auteurs

Morgane Faure (M)

APHP-6 Sorbonne Université, site Pitié-Salpêtrière, Service de Médecine Intensive - Réanimation (Département R3S), Paris, France.

Maxens Decavèle (M)

APHP-6 Sorbonne Université, site Pitié-Salpêtrière, Service de Médecine Intensive - Réanimation (Département R3S), Paris, France; and Sorbonne Université, INSERM, UMRS1158 Neurophysiologie Respiratoire Expérimentale et Clinique, Paris, France. maxens.decavele@aphp.fr.

Elise Morawiec (E)

APHP-6 Sorbonne Université, site Pitié-Salpêtrière, Service de Médecine Intensive - Réanimation (Département R3S), Paris, France.

Martin Dres (M)

APHP-6 Sorbonne Université, site Pitié-Salpêtrière, Service de Médecine Intensive - Réanimation (Département R3S), Paris, France; and Sorbonne Université, INSERM, UMRS1158 Neurophysiologie Respiratoire Expérimentale et Clinique, Paris, France.

Nicolas Gatulle (N)

APHP-6 Sorbonne Université, site Pitié-Salpêtrière, Service de Médecine Intensive - Réanimation (Département R3S), Paris, France.

Julien Mayaux (J)

APHP-6 Sorbonne Université, site Pitié-Salpêtrière, Service de Médecine Intensive - Réanimation (Département R3S), Paris, France.

François Stefanescu (F)

APHP-6 Sorbonne Université, site Pitié-Salpêtrière, Service de Médecine Intensive - Réanimation (Département R3S), Paris, France.

Julien Caliez (J)

APHP-6 Sorbonne Université, site Pitié-Salpêtrière, Service de Médecine Intensive - Réanimation (Département R3S), Paris, France.

Thomas Similowski (T)

Sorbonne Université, INSERM, UMRS1158 Neurophysiologie Respiratoire Expérimentale et Clinique, Paris, France; and APHP-6 Sorbonne Université, site Pitié-Salpêtrière, Département R3S (Respiration, Réanimation, Réhabilitation respiratoire, Sommeil), Paris, France.

Julie Delemazure (J)

APHP-6 Sorbonne Université, site Pitié-Salpêtrière, Service de Médecine Intensive - Réanimation (Département R3S), Paris, France.

Alexandre Demoule (A)

APHP-6 Sorbonne Université, site Pitié-Salpêtrière, Service de Médecine Intensive - Réanimation (Département R3S), Paris, France; and Sorbonne Université, INSERM, UMRS1158 Neurophysiologie Respiratoire Expérimentale et Clinique, Paris, France.

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