Synchronous Hürthle cell and medullary thyroid carcinomas.

Ear, nose and throat/otolaryngology Endocrine cancer Head and neck cancer Otolaryngology / ENT Pathology

Journal

BMJ case reports
ISSN: 1757-790X
Titre abrégé: BMJ Case Rep
Pays: England
ID NLM: 101526291

Informations de publication

Date de publication:
31 May 2022
Historique:
pmc-release: 30 05 2024
entrez: 31 5 2022
pubmed: 1 6 2022
medline: 3 6 2022
Statut: epublish

Résumé

Hürthle cell carcinoma (HCC) and medullary thyroid carcinomas (MTC) are uncommon histological subtypes of thyroid cancers, each accounting for around 3% of all thyroid cancers. A septuagenarian woman with a history of multiple primary cancer diagnoses presented with a growing left-sided neck lump. A diagnostic left thyroid lobectomy was performed, and pathological examination found two separate malignant foci: one HCC and an MTC. The patient developed left-sided HCC nodal metastasis, and following several multidisciplinary team discussions, a right completion lobectomy with left lateral neck dissection was performed, revealing further intrathyroidal MTC and extranodal extension of HCC. We present this as the first reported case of a collision tumour of HCC and MTC, and review the available literature regarding collision tumours and their management.

Identifiants

pubmed: 35641084
pii: 15/5/e248879
doi: 10.1136/bcr-2022-248879
pmc: PMC9157358
pii:
doi:

Types de publication

Case Reports Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© BMJ Publishing Group Limited 2022. No commercial re-use. See rights and permissions. Published by BMJ.

Déclaration de conflit d'intérêts

Competing interests: None declared.

Auteurs

Zhu Hui Yeap (ZH)

Otolaryngology, NHS Highland, Inverness, UK zhuhui.yeap@nhs.scot.

Sam Arman (S)

Otolaryngology, NHS Highland, Inverness, UK.

Grant Stenhouse (G)

Pathology, NHS Highland, Inverness, UK.

Aidah Isa (A)

Otolaryngology, NHS Highland, Inverness, UK.

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Classifications MeSH