The evaluation of tactile dysfunction in the hand in type 1 diabetes: a novel method based on haptics.
Diabetic neuropathies
Hand
Haptic technology
Motion perception
Touch
Vibration
Journal
Acta diabetologica
ISSN: 1432-5233
Titre abrégé: Acta Diabetol
Pays: Germany
ID NLM: 9200299
Informations de publication
Date de publication:
Aug 2022
Aug 2022
Historique:
received:
04
02
2022
accepted:
05
05
2022
pubmed:
1
6
2022
medline:
2
7
2022
entrez:
31
5
2022
Statut:
ppublish
Résumé
We present an innovative method based on haptics for the evaluation of the sense of touch in the hand, in people affected by type 1 diabetes. Forty individuals affected by diabetes and 20 healthy controls took part in the study; the diabetes group was further divided into two subgroups based on vibration sensitivity in the lower limb. By means of a novel haptic device, tactile sensitivity in the fingertip was measured as the ability of the participants to discriminate slip motion speed. Tactile sensitivity was significantly lower in individuals affected by diabetes as compared to controls. Depending on the subgroup, the difference from the controls was equal to 0.11 (95% CI from 0.029 to 0.186) and to 0.267 (95% CI from 0.198 to 0.336). Within the diabetes group, tactile sensitivity correlated with vibration sensitivity in the upper (p = 0.001) and lower limb (p = 0.003). A significant relationship between nerve conduction parameters and tactile sensitivity was found (p = 0.03). Finally, we combined the different predictors (clinical, vibratory and electroneurography data) by using cluster analysis; tactile sensitivity was found to be significantly different between different clusters (p = 0.004). Early signs of tactile dysfunction in the hand were found in individuals affected by diabetes, even in absence of diabetic neuropathy. The protocol presented in this study is a promising tool for the assessment of tactile dysfunction in the hand in people affected by type 1 diabetes.
Identifiants
pubmed: 35641837
doi: 10.1007/s00592-022-01903-1
pii: 10.1007/s00592-022-01903-1
pmc: PMC9242965
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1073-1082Subventions
Organisme : Italian Ministry of Health, Ricerca Corrente, IRCCS Fondazione Santa Lucia and Ricerca Finalizzata
ID : RF-2018-12365985
Organisme : Italian Ministry of University and Research PRIN
ID : 2017SB48FP
Organisme : Italian Ministry of University and Research Grant "Beyond Borders
ID : E89C20000700005
Informations de copyright
© 2022. The Author(s).
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