Combining galacto-oligosaccharides and 2'-fucosyllactose alters their fermentation kinetics by infant fecal microbiota and influences AhR-receptor dependent cytokine responses in immature dendritic cells.


Journal

Food & function
ISSN: 2042-650X
Titre abrégé: Food Funct
Pays: England
ID NLM: 101549033

Informations de publication

Date de publication:
20 Jun 2022
Historique:
pubmed: 2 6 2022
medline: 22 6 2022
entrez: 1 6 2022
Statut: epublish

Résumé

Galacto-oligosaccharides (GOS) and 2'-fucosyllactose (2'-FL) are non-digestible carbohydrates (NDCs) that are often added to infant formula to replace the functionalities of human milk oligosaccharides (HMOs). It is not known if combining GOS and 2'-FL will affect their fermentation kinetics and subsequent immune-modulatory effects such as AhR-receptor stimulation. Here, we used an

Identifiants

pubmed: 35642586
doi: 10.1039/d2fo00550f
pmc: PMC9208271
doi:

Substances chimiques

Cytokines 0
Oligosaccharides 0
Trisaccharides 0
Galactose X2RN3Q8DNE
2'-fucosyllactose XO2533XO8R

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

6510-6521

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Auteurs

Renate Akkerman (R)

Immunoendocrinology, Division of Medical Biology, Department of Pathology and Medical Biology, University of Groningen and University Medical Centre Groningen, Groningen, The Netherlands. r.akkerman@umcg.nl.

Madelon J Logtenberg (MJ)

Laboratory of Food Chemistry, Wageningen University & Research, Wageningen, The Netherlands.

Martin Beukema (M)

Immunoendocrinology, Division of Medical Biology, Department of Pathology and Medical Biology, University of Groningen and University Medical Centre Groningen, Groningen, The Netherlands. r.akkerman@umcg.nl.

Bart J de Haan (BJ)

Immunoendocrinology, Division of Medical Biology, Department of Pathology and Medical Biology, University of Groningen and University Medical Centre Groningen, Groningen, The Netherlands. r.akkerman@umcg.nl.

Marijke M Faas (MM)

Immunoendocrinology, Division of Medical Biology, Department of Pathology and Medical Biology, University of Groningen and University Medical Centre Groningen, Groningen, The Netherlands. r.akkerman@umcg.nl.

Erwin G Zoetendal (EG)

Laboratory of Microbiology, Wageningen University & Research, Wageningen, The Netherlands.

Henk A Schols (HA)

Laboratory of Food Chemistry, Wageningen University & Research, Wageningen, The Netherlands.

Paul de Vos (P)

Immunoendocrinology, Division of Medical Biology, Department of Pathology and Medical Biology, University of Groningen and University Medical Centre Groningen, Groningen, The Netherlands. r.akkerman@umcg.nl.

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Classifications MeSH