Posttraumatic stress disorder symptoms and timing of menopause and gynecological surgery in the Nurses' Health Study II.

Female Gynecologic Surgical Procedures Humans Menopause Nurses Prospective Studies Risk Factors Stress Disorders, Post-Traumatic / complications
Gynecological surgery Menopause Posttraumatic stress disorder Trauma

Journal

Journal of psychosomatic research
ISSN: 1879-1360
Titre abrégé: J Psychosom Res
Pays: England
ID NLM: 0376333

Informations de publication

Date de publication:
08 2022
Historique:
received: 10 02 2022
revised: 16 05 2022
accepted: 17 05 2022
pubmed: 2 6 2022
medline: 16 6 2022
entrez: 1 6 2022
Statut: ppublish

Résumé

Earlier menopause, either natural or through gynecologic surgeries, has been associated with various negative health sequelae. While posttraumatic stress disorder (PTSD) has been linked to dysregulated biological processes, including reproductive system changes that could alter menopausal timing, little work has examined whether trauma and PTSD are associated with greater risk of early cessation of menses. Data are from 46,639 women in the Nurses' Health Study II, a prospective cohort study of women followed for up to 26 years. Lifetime trauma and PTSD symptoms were assessed with the Brief Trauma Questionnaire and a PTSD symptom screener in 2008. Age at cessation of menses and reason for cessation of menses (i.e., natural menopause, gynecologic surgery including hysterectomy and/or bilateral salpingo-oophorectomy [BSO]) were assessed. Cox proportional hazards models estimated hazards ratios (HR) of cessation of menses (separately for naturally or surgically) associated with trauma alone or PTSD symptoms, relative to no trauma, adjusting for covariates. Trauma/PTSD status was associated with earlier cessation of menses due to surgery, but not natural menopause. Women with trauma exposure, low, and high PTSD symptoms had higher hazard of cessation of menses due to surgery relative to those with no trauma exposure (HR Women who experienced trauma and PTSD may be at elevated risk for common gynecological surgeries premenopausally, potentially due to increased clinical indications or gynecological conditions.

Sections du résumé

BACKGROUND
Earlier menopause, either natural or through gynecologic surgeries, has been associated with various negative health sequelae. While posttraumatic stress disorder (PTSD) has been linked to dysregulated biological processes, including reproductive system changes that could alter menopausal timing, little work has examined whether trauma and PTSD are associated with greater risk of early cessation of menses.
METHODS
Data are from 46,639 women in the Nurses' Health Study II, a prospective cohort study of women followed for up to 26 years. Lifetime trauma and PTSD symptoms were assessed with the Brief Trauma Questionnaire and a PTSD symptom screener in 2008. Age at cessation of menses and reason for cessation of menses (i.e., natural menopause, gynecologic surgery including hysterectomy and/or bilateral salpingo-oophorectomy [BSO]) were assessed. Cox proportional hazards models estimated hazards ratios (HR) of cessation of menses (separately for naturally or surgically) associated with trauma alone or PTSD symptoms, relative to no trauma, adjusting for covariates.
RESULTS
Trauma/PTSD status was associated with earlier cessation of menses due to surgery, but not natural menopause. Women with trauma exposure, low, and high PTSD symptoms had higher hazard of cessation of menses due to surgery relative to those with no trauma exposure (HR
CONCLUSIONS
Women who experienced trauma and PTSD may be at elevated risk for common gynecological surgeries premenopausally, potentially due to increased clinical indications or gynecological conditions.

Identifiants

DOI: 10.1016/j.jpsychores.2022.110947 PMID: 35644086 PMC: PMC9197996
pubmed: 35644086
pii: S0022-3999(22)00232-X
doi: 10.1016/j.jpsychores.2022.110947
pmc: PMC9197996
mid: NIHMS1812688
pii:
doi:

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, U.S. Gov't, Non-P.H.S.

Langues

eng

Sous-ensembles de citation

IM

Pagination

110947

Subventions

Organisme : NHLBI NIH HHS
ID : K24 HL123565
Pays : United States
Organisme : NIMH NIH HHS
ID : R01 MH101269
Pays : United States
Organisme : NIMH NIH HHS
ID : T32 MH017119
Pays : United States
Organisme : NCI NIH HHS
ID : U01 CA176726
Pays : United States

Informations de copyright

Published by Elsevier Inc.

Références

J Anxiety Disord. 2013 Jan;27(1):33-46
pubmed: 23247200
Gynecol Endocrinol. 2020 Jan;36(1):49-54
pubmed: 31269828
Adolesc Health Med Ther. 2013 Jan 18;4:1-21
pubmed: 24600293
Am J Epidemiol. 1987 Aug;126(2):319-25
pubmed: 3605058
Curr Psychiatry Rep. 2018 Jul 17;20(7):52
pubmed: 30019147
Maturitas. 2010 Feb;65(2):161-6
pubmed: 19733988
Obstet Gynecol. 2010 Nov;116(5):1088-95
pubmed: 20966693
Am J Obstet Gynecol. 2016 Mar;214(3):352.e1-352.e13
pubmed: 26475424
Ann Intern Med. 2017 Aug 15;167(4):268-274
pubmed: 28693043
Cochrane Database Syst Rev. 2019 Aug 29;8:CD000329
pubmed: 31463964
Gerontologist. 2016 Feb;56 Suppl 1:S67-77
pubmed: 26768393
Soc Sci Med. 1998 May;46(10):1381-96
pubmed: 9665569
Menopause. 2020 Sep 04;28(1):8-11
pubmed: 32898023
Epidemiology. 2018 Sep;29(5):e45-e47
pubmed: 29912013
Arch Gen Psychiatry. 2003 Jan;60(1):29-36
pubmed: 12511170
Psychiatr Ann. 2016;46:527-532
pubmed: 27990033
Pain. 2011 Oct;152(10):2233-2240
pubmed: 21665366
Curr Psychiatry Rep. 2017 Aug 29;19(10):75
pubmed: 28852965
Med Care. 1993 Mar;31(3):247-63
pubmed: 8450681
Menopause. 2012 Jun;19(6):616-21
pubmed: 22648302
Am J Obstet Gynecol. 2019 Oct;221(4):318.e1-318.e9
pubmed: 31125544
Menopause. 2019 Dec;26(12):1395-1404
pubmed: 31479036
Geburtshilfe Frauenheilkd. 2020 Mar;80(3):288-299
pubmed: 32139918
Hum Reprod. 2016 Dec;31(12):2856-2864
pubmed: 27798047
JAMA Intern Med. 2019 Jan 1;179(1):80-87
pubmed: 30453319
Cancer Epidemiol Biomarkers Prev. 2021 Mar;30(3):492-498
pubmed: 33355196
Am J Psychiatry. 1999 Jun;156(6):908-11
pubmed: 10360131
Obstet Gynecol. 2011 Dec;118(6):1280-1286
pubmed: 22105256
Obstet Gynecol. 2013 Aug;122(2 Pt 1):233-241
pubmed: 23969789
Obstet Gynecol. 2011 Dec;118(6):1271-1279
pubmed: 22067716
Hum Reprod. 2018 Sep 1;33(9):1657-1668
pubmed: 30016439
Curr Psychiatry Rep. 2018 Oct 26;20(12):116
pubmed: 30367276
JAMA. 1993 May 12;269(18):2398-402
pubmed: 8479066
Am J Obstet Gynecol. 2010 Jun;202(6):514-21
pubmed: 20430357
Womens Midlife Health. 2020 Sep 01;6:9
pubmed: 32884826
Maturitas. 2018 Nov;117:64-77
pubmed: 30314564
Mol Psychiatry. 2014 Nov;19(11):1156-62
pubmed: 25245500
Womens Health Issues. 2020 Sep - Oct;30(5):359-365
pubmed: 32712008
Am J Prev Med. 1994 Mar-Apr;10(2):77-84
pubmed: 8037935
Biol Psychiatry. 2020 May 15;87(10):885-897
pubmed: 31932029
Health Psychol. 2018 May;37(5):407-416
pubmed: 29698016
J Clin Psychol Med Settings. 2016 Jun;23(2):160-80
pubmed: 26868222
Acta Psychiatr Scand. 2005 Apr;111(4):291-9
pubmed: 15740465
Obstet Gynecol. 2007 Apr;109(4):902-8
pubmed: 17400852
Maturitas. 2008 Dec 20;61(4):287-98
pubmed: 19019585
Womens Health Issues. 2012 Sep;22(5):e461-71
pubmed: 22944901
Circulation. 2015 Jul 28;132(4):251-9
pubmed: 26124186

Auteurs

Kristen Nishimi (K)

Mental Health Service, San Francisco Veterans Affairs Healthcare System, San Francisco, CA, USA; Department of Psychiatry and Weill Institute for Neurosciences, University of California San Francisco, San Francisco, CA, USA. Electronic address: Kristen.nishimi@ucsf.edu.

Rebecca C Thurston (RC)

Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA; Department of Epidemiology, University of Pittsburgh, Pittsburgh, PA, USA; Department of Psychology, University of Pittsburgh, Pittsburgh, PA, USA.

Lori B Chibnik (LB)

Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA; Department of Neurology, Massachusetts General Hospital, Boston, MA, USA.

Andrea L Roberts (AL)

Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, USA.

Jennifer A Sumner (JA)

Department of Psychology, University of California, Los Angeles, Los Angeles, CA, USA.

Rebecca B Lawn (RB)

Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.

Shelley S Tworoger (SS)

Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA; Department of Cancer Epidemiology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA.

Yongjoo Kim (Y)

Department of Social and Behavioral Sciences, Harvard T.H. Chan School of Public Health, Boston, MA, USA; College of Korean Medicine, Sangji University, Wonju, Republic of Korea.

Karestan C Koenen (KC)

Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA; Department of Social and Behavioral Sciences, Harvard T.H. Chan School of Public Health, Boston, MA, USA.

Laura D Kubzansky (LD)

Department of Social and Behavioral Sciences, Harvard T.H. Chan School of Public Health, Boston, MA, USA.

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Classifications MeSH

questionsmedicales.fr › Procédures de chirurgie opératoire › Procédures de chirurgie urogénitale › Procédures de chirurgie gynécologique › Posttraumatic stress disorder symptoms and...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Posttraumatic stress disorder symptoms and...
questionsmedicales.fr › Phénomènes physiologiques des appareils urinaire et reproducteur › Phénomènes physiologiques de la reproduction › Développement sexuel › Climatère › Ménopause › Posttraumatic stress disorder symptoms and...
questionsmedicales.fr › Établissements, main d'oeuvre et services de soins de santé › Personnel de santé › Infirmières et infirmiers › Posttraumatic stress disorder symptoms and...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Caractéristiques des études épidémiologiques › Études épidémiologiques › Études de cohortes › Études prospectives › Posttraumatic stress disorder symptoms and...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Statistiques comme sujet › Probabilité › Risque › Facteurs de risque › Posttraumatic stress disorder symptoms and...
questionsmedicales.fr › Troubles mentaux › Troubles liés aux traumatismes et au stress › Troubles de stress traumatique › Troubles de stress post-traumatique › Posttraumatic stress disorder symptoms and...