Single Versus Dual Antiplatelet Therapy following Left Atrial Appendage Occlusion in Patients With High Bleeding Risk.
Journal
Current problems in cardiology
ISSN: 1535-6280
Titre abrégé: Curr Probl Cardiol
Pays: Netherlands
ID NLM: 7701802
Informations de publication
Date de publication:
Sep 2022
Sep 2022
Historique:
received:
10
05
2022
accepted:
23
05
2022
pubmed:
2
6
2022
medline:
10
8
2022
entrez:
1
6
2022
Statut:
ppublish
Résumé
Our study aims to compare the utility of single antiplatelet therapy (SAPT) with dual antiplatelet therapy (DAPT) following Left atrial appendage occlusion in patients whose post-procedural oral anticoagulation therapy was deemed high-risk or contraindicated. A total of 14 observational studies with 3,151 patients were included. Our study demonstrates that SAPT and DAPT were similar in preventing device-related thrombosis. Although SAPT and DAPT had a tendency toward a higher risk for stroke and major bleeding respectively, these differences did not reach statistical significance. Large-scale Randomized Controlled Studies are warranted to validate if our results could be translated into clinical practice.
Identifiants
pubmed: 35644502
pii: S0146-2806(22)00166-9
doi: 10.1016/j.cpcardiol.2022.101269
pii:
doi:
Substances chimiques
Anticoagulants
0
Platelet Aggregation Inhibitors
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
101269Informations de copyright
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