Comprehensive Transcriptional Profiling and Mouse Phenotyping Reveals Dispensable Role for Adipose Tissue Selective Long Noncoding RNA
adipose tissue remodelling
brown adipose tissue
long noncoding RNAs
Journal
Non-coding RNA
ISSN: 2311-553X
Titre abrégé: Noncoding RNA
Pays: Switzerland
ID NLM: 101652294
Informations de publication
Date de publication:
06 May 2022
06 May 2022
Historique:
received:
11
04
2022
revised:
29
04
2022
accepted:
04
05
2022
entrez:
1
6
2022
pubmed:
2
6
2022
medline:
2
6
2022
Statut:
epublish
Résumé
Cold and nutrient-activated brown adipose tissue (BAT) is capable of increasing systemic energy expenditure via the uncoupled respiration and secretion of endocrine factors, thereby protecting mice against diet-induced obesity and improving insulin response and glucose tolerance in men. Long non-coding RNAs (lncRNAs) have recently been identified as fine-tuning regulators of cellular function. While certain lncRNAs have been functionally characterised in adipose tissue, their overall contribution in the activation of BAT remains elusive. We identified lncRNAs correlating to interscapular brown adipose tissue (iBAT) function in a high fat diet (HFD) and cold stressed mice. We focused on
Identifiants
pubmed: 35645339
pii: ncrna8030032
doi: 10.3390/ncrna8030032
pmc: PMC9149892
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : European Research Council
ID : 675014
Pays : International
Organisme : Danish Diabetes Academy
ID : 00000
Organisme : Novo Nordisk Foundation
ID : NNF18OC0033444
Références
J Cell Biochem. 2008 Aug 15;104(6):2241-7
pubmed: 18452164
Bioinformatics. 2006 Jul 1;22(13):1600-7
pubmed: 16606683
Nat Methods. 2020 Jul;17(7):685-688
pubmed: 32572232
Lancet. 2016 Aug 20;388(10046):776-86
pubmed: 27423262
Elife. 2019 Jan 08;8:
pubmed: 30620332
J Clin Invest. 2011 Jan;121(1):96-105
pubmed: 21123942
Nat Cell Biol. 2019 May;21(5):542-551
pubmed: 31048766
Nat Rev Drug Discov. 2013 Jun;12(6):433-46
pubmed: 23722346
Trends Genet. 2018 Nov;34(11):867-882
pubmed: 30177410
Cell Metab. 2015 May 5;21(5):764-776
pubmed: 25921091
Cell Syst. 2018 Nov 28;7(5):537-547.e3
pubmed: 30447999
Nature. 2015 Jan 29;517(7536):583-8
pubmed: 25494202
Nat Commun. 2018 Sep 6;9(1):3622
pubmed: 30190464
PLoS Biol. 2017 Aug 1;15(8):e2002176
pubmed: 28763438
Nature. 1993 Dec 23-30;366(6457):740-2
pubmed: 8264795
Cell. 2015 Feb 12;160(4):595-606
pubmed: 25640239
Genome Biol. 2014;15(12):550
pubmed: 25516281
Sci Rep. 2017 Nov 22;7(1):16082
pubmed: 29167565
Nat Rev Genet. 2020 Feb;21(2):102-117
pubmed: 31729473
Nature. 2012 Sep 6;489(7414):101-8
pubmed: 22955620
Bioinformatics. 2019 Jun 1;35(12):2084-2092
pubmed: 30395178
Mol Metab. 2017 Oct;6(10):1313-1320
pubmed: 29031730
Trends Cell Biol. 2016 May;26(5):313-326
pubmed: 26874575
Nat Commun. 2020 Jan 31;11(1):644
pubmed: 32005828
Cell Metab. 2007 Jul;6(1):38-54
pubmed: 17618855
Genome Res. 2012 Sep;22(9):1775-89
pubmed: 22955988
J Cell Physiol. 2019 Aug;234(10):16692-16702
pubmed: 30807657
Annu Rev Genet. 2012;46:1-19
pubmed: 22905871
Proc Natl Acad Sci U S A. 2013 Feb 26;110(9):3387-92
pubmed: 23401553
Elife. 2015 Dec 19;4:e08890
pubmed: 26687005
Nat Rev Drug Discov. 2017 Mar;16(3):167-179
pubmed: 27444227
Endocr Rev. 2020 Jan 1;41(1):
pubmed: 31638161
Lancet. 2016 Apr 2;387(10026):1377-1396
pubmed: 27115820
Physiol Rev. 2004 Jan;84(1):277-359
pubmed: 14715917
Nat Biotechnol. 2014 Dec;32(12):1262-7
pubmed: 25184501
Diabetes. 2019 May;68(5):887-896
pubmed: 31010880
Exp Hematol. 2020 Jun;86:1-14
pubmed: 32422232
J Mol Cell Biol. 2018 Apr 1;10(2):175-178
pubmed: 29420831
Cell Rep. 2020 Aug 4;32(5):107998
pubmed: 32755590
Nat Methods. 2012 Mar 04;9(4):357-9
pubmed: 22388286
EMBO Rep. 2021 Jul 5;22(7):e51289
pubmed: 34056831
Bioinformatics. 2013 Jan 1;29(1):15-21
pubmed: 23104886
J Cell Biochem. 2009 Jan 1;106(1):103-8
pubmed: 19009554
Am J Physiol Endocrinol Metab. 2007 Aug;293(2):E444-52
pubmed: 17473055
J Lipid Res. 2012 Dec;53(12):2791-6
pubmed: 22993232
Compr Physiol. 2017 Sep 12;7(4):1281-1306
pubmed: 28915325
Endocr Rev. 2016 Aug;37(4):403-16
pubmed: 27337111
Mol Aspects Med. 2019 Aug;68:90-100
pubmed: 31283940
Front Genet. 2015 Jan 26;6:2
pubmed: 25674102
Nat Methods. 2017 Apr;14(4):417-419
pubmed: 28263959
Trends Genet. 2010 Oct;26(10):425-30
pubmed: 20708291
Mol Cell Biol. 2012 Sep;32(17):3452-63
pubmed: 22733994
Mol Biosyst. 2016 Feb;12(2):477-9
pubmed: 26661513
Nucleic Acids Res. 2013 Apr 1;41(6):e74
pubmed: 23335781
J Clin Invest. 2001 Oct;108(8):1205-13
pubmed: 11602628
Lancet. 2009 Mar 28;373(9669):1083-96
pubmed: 19299006
Nat Rev Endocrinol. 2018 Feb;14(2):77-87
pubmed: 29052591
Cell. 2014 Jan 16;156(1-2):20-44
pubmed: 24439368