Risk Assessment of Cnm-Positive
Cnm
Streptococcus mutans (S. mutans)
cerebral microbleeds (CMBs)
dental caries
intracerebral hemorrhage (ICH)
small vessel disease (SVD)
stroke
Journal
Frontiers in neurology
ISSN: 1664-2295
Titre abrégé: Front Neurol
Pays: Switzerland
ID NLM: 101546899
Informations de publication
Date de publication:
2022
2022
Historique:
received:
16
11
2021
accepted:
19
04
2022
entrez:
1
6
2022
pubmed:
2
6
2022
medline:
2
6
2022
Statut:
epublish
Résumé
The role of commensal microbiota in systemic diseases, including brain diseases, has attracted increasing attention. Oral infectious diseases, such as dental caries and periodontitis, are also involved in cerebrovascular diseases and cognitive impairment. Cerebral microbleeds (CMBs) and intracerebral hemorrhage due to small vessel disease (SVD), are presumably associated with a high risk of vascular cognitive impairment and stroke. We previously reported that Fifteen domestic institutes will be enlisted to enroll 230 patients who have at least one CMB in the deep brain area and develop a stroke within the past year. The prevalence of Cnm-positive The 2-year longitudinal prospective cohort study is expected to establish the role of Cnm-positive
Identifiants
pubmed: 35645961
doi: 10.3389/fneur.2022.816147
pmc: PMC9133813
doi:
Types de publication
Journal Article
Langues
eng
Pagination
816147Informations de copyright
Copyright © 2022 Hosoki, Hattori, Saito, Takegami, Tonomura, Yamamoto, Ikeda, Hosomi, Oishi, Morita, Miyamoto, Nomura, Nakano and Ihara.
Déclaration de conflit d'intérêts
MI reports personal fees from Daiichi Sankyo, Eisai, and Bayer, and grants from Panasonic, Bristol-Myers Squibb, and Otsuka Pharmaceutical, outside the submitted work. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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