Early identification of patients with Chagas disease at risk of developing cardiomyopathy using 2-D speckle tracking strain:

Chagas cardiomyopathy Chagas disease Echocardiography Strain imaging

Journal

International journal of cardiology. Heart & vasculature
ISSN: 2352-9067
Titre abrégé: Int J Cardiol Heart Vasc
Pays: Ireland
ID NLM: 101649525

Informations de publication

Date de publication:
Aug 2022
Historique:
received: 16 03 2022
revised: 27 04 2022
accepted: 17 05 2022
entrez: 1 6 2022
pubmed: 2 6 2022
medline: 2 6 2022
Statut: epublish

Résumé

Chagas disease is an endemic protozoan disease with high prevalence in Latin America. Of those infected, 20-30% will develop chronic Chagas cardiomyopathy (CCC) however, prediction using existing clinical criteria remains poor. In this study, we investigated the utility of left ventricular (LV) echocardiographic speckle-tracking global longitudinal strain (GLS) for early detection of CCC. 139 asymptomatic Baseline LV GLS in participants with CCC stage A or B was predictive of progression within 1-year and may guide timing of clinical follow-up and promote early detection or treatment.

Sections du résumé

Background UNASSIGNED
Chagas disease is an endemic protozoan disease with high prevalence in Latin America. Of those infected, 20-30% will develop chronic Chagas cardiomyopathy (CCC) however, prediction using existing clinical criteria remains poor. In this study, we investigated the utility of left ventricular (LV) echocardiographic speckle-tracking global longitudinal strain (GLS) for early detection of CCC.
Methods and results UNASSIGNED
139 asymptomatic
Conclusion UNASSIGNED
Baseline LV GLS in participants with CCC stage A or B was predictive of progression within 1-year and may guide timing of clinical follow-up and promote early detection or treatment.

Identifiants

pubmed: 35647262
doi: 10.1016/j.ijcha.2022.101060
pii: S2352-9067(22)00109-9
pmc: PMC9136131
doi:

Types de publication

Journal Article

Langues

eng

Pagination

101060

Informations de copyright

© 2022 Published by Elsevier B.V.

Déclaration de conflit d'intérêts

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

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Auteurs

Sithu Win (S)

University of California San Francisco, San Francisco, CA, USA.

Monica Miranda-Schaeubinger (M)

Johns Hopkins University, Bloomberg School of Public Health, Baltimore, MD, USA.

Ronald Gustavo Durán Saucedo (R)

Universidad Católica Boliviana San Pablo, Bolivia.

Paula Carballo Jimenez (P)

Imperial College of London, UK.

Jorge Flores (J)

Universidad Católica Boliviana San Pablo, Bolivia.

Brandon Mercado-Saavedra (B)

Department of Biochemistry, University of Cambridge, UK.

Lola Camila Telleria (L)

Pontificia Universidad Católica de Chile, Santiago, Chile.

Anne Raafs (A)

Maastricht University, Cardiovascular Research Institute Maastricht (CARIM), Division of Cardiology, Maastricht, Netherlands.

Manuela Verastegui (M)

Universidad Peruana Cayetano Heredia, Lima, Peru.

Caryn Bern (C)

University of California San Francisco, San Francisco, CA, USA.

Freddy Tinajeros (F)

Universidad Católica Boliviana San Pablo, Bolivia.

Stephane Heymans (S)

Maastricht University, Cardiovascular Research Institute Maastricht (CARIM), Division of Cardiology, Maastricht, Netherlands.

Rachel Marcus (R)

MedStar Heart & Vascular Institute, Baltimore, MD, USA.

Robert H Gilman (RH)

Johns Hopkins University, Bloomberg School of Public Health, Baltimore, MD, USA.

Monica Mukherjee (M)

Johns Hopkins University, Division of Cardiology, Baltimore, MD, USA.

Classifications MeSH