Multidisciplinary residential program for the treatment of obesity: how body composition assessed by DXA and blood chemistry parameters change during hospitalization and which variations in body composition occur from discharge up to 1-year follow-up.
Body composition
Hospitalization
Multidisciplinary residential program
Obesity
Journal
Eating and weight disorders : EWD
ISSN: 1590-1262
Titre abrégé: Eat Weight Disord
Pays: Germany
ID NLM: 9707113
Informations de publication
Date de publication:
Oct 2022
Oct 2022
Historique:
received:
03
12
2021
accepted:
30
04
2022
pubmed:
2
6
2022
medline:
15
10
2022
entrez:
1
6
2022
Statut:
ppublish
Résumé
Obesity is a chronic disease characterized by a complex variable clinical presentation with comorbidities. A multidisciplinary residential program (MRP) represents one of the best options for treating obesity. The purpose of this study was to evaluate the effectiveness of 8-week MRP on weight loss, body composition assessed by DXA, and metabolic blood parameters between entry (T0) and discharge (T1). The secondary endpoint was the evaluation of the patients' adherence to diet during the check-up outpatient visits, at 2 (T2), 6 (T3), and 12 (T4) months after discharge. 168 subjects were enrolled (61 males and 117 females, aged 58.5 ± 13 years, BMI 41.3 ± 6 kg/m There was a statistically significant improvement of all parameters investigated: total mass (- 5.68 kg), fat mass (- 4416.85 g), fat mass index (- 1724.56), visceral adipose tissue (- 332.76 g), arm circumference (- 1.63 cm) and calf circumference (- 1.16 cm). As it is reasonable to expect, even the fat free mass has been reduced (- 1236.03 g); however, the skeletal muscle index was not affected. Statistically significant improvement in glycaemic and lipid profile were reported. The BMI average reduction continued from discharge until T4. No statistically significant changes in fat free mass and visceral adipose tissue (VAT) were reported during a year of follow-up. The present study demonstrated the clinical benefits of 8-week MRP, which includes hypocaloric diet, physical exercise, and psychological support. III, evidence obtained from cohort or case-control analytic studies.
Identifiants
pubmed: 35648314
doi: 10.1007/s40519-022-01412-8
pii: 10.1007/s40519-022-01412-8
pmc: PMC9556418
doi:
Substances chimiques
Lipids
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
2701-2711Informations de copyright
© 2022. The Author(s).
Références
McCafferty BJ, Hill JO, Gunn AJ (2020) Obesity: scope, lifestyle interventions, and medical management. Tech Vasc Interv Radiol 23:100653
doi: 10.1016/j.tvir.2020.100653
Singh GM, Danaei G, Farzadfar F et al (2013) The age-specific quantitative effects of metabolic risk factors on cardiovascular diseases and diabetes: a pooled analysis. PLoS ONE. https://doi.org/10.1371/journal.pone.0065174
doi: 10.1371/journal.pone.0065174
pubmed: 24391934
pmcid: 3877255
Czernichow S, Kengne AP, Stamatakis E et al (2011) Body mass index, waist circumference and waist-hip ratio: Which is the better discriminator of cardiovascular disease mortality risk? Evidence from an individual-participant meta-analysis of 82864 participants from nine cohort studies. Obes Rev 12:680–687. https://doi.org/10.1111/j.1467-789X.2011.00879.x
doi: 10.1111/j.1467-789X.2011.00879.x
pubmed: 21521449
pmcid: 4170776
Lu JL, Molnar MZ, Naseer A et al (2015) Association of age and BMI with kidney function and mortality: a cohort study. Lancet Diabetes Endocrinol 3:704–714. https://doi.org/10.1016/S2213-8587(15)00128-X
doi: 10.1016/S2213-8587(15)00128-X
pubmed: 26235959
pmcid: 4547884
Lauby-Secretan B, Scoccianti C, Loomis D et al (2016) Body fatness and cancer—viewpoint of the IARC Working Group. N Engl J Med 375:794–798. https://doi.org/10.1056/nejmsr1606602
doi: 10.1056/nejmsr1606602
pubmed: 27557308
pmcid: 6754861
Pépin JL, Timsit JF, Tamisier R et al (2016) Prevention and care of respiratory failure in obese patients. Lancet Respir Med 4:407–418
doi: 10.1016/S2213-2600(16)00054-0
Anandacoomarasamy A, Caterson I, Sambrook P et al (2008) The impact of obesity on the musculoskeletal system. Int J Obes 32:211–222
doi: 10.1038/sj.ijo.0803715
Anstey KJ, Cherbuin N, Budge M, Young J (2011) Body mass index in midlife and late-life as a risk factor for dementia: a meta-analysis of prospective studies. Obes Rev. https://doi.org/10.1111/j.1467-789X.2010.00825.x
doi: 10.1111/j.1467-789X.2010.00825.x
pubmed: 21348917
Budui S, Bigolin F, Giordano F et al (2019) Effects of an intensive inpatient rehabilitation program in elderly patients with obesity. Obes Facts 12:199–210. https://doi.org/10.1159/000497461
doi: 10.1159/000497461
pubmed: 30928989
pmcid: 6547270
Ross R, Bradshaw AJ (2009) The future of obesity reduction: beyond weight loss. Nat Rev Endocrinol 56(5):319–325. https://doi.org/10.1038/nrendo.2009.78
doi: 10.1038/nrendo.2009.78
Yumuk V, Tsigos C, Fried M et al (2015) European guidelines for obesity management in adults. Obes Facts 8:402–424. https://doi.org/10.1159/000442721
doi: 10.1159/000442721
pubmed: 26641646
pmcid: 5644856
Apovian CM, Aronne LJ, Bessesen DH et al (2015) Pharmacological management of obesity: an endocrine society clinical practice guideline. J Clin Endocrinol Metab 100:342–362. https://doi.org/10.1210/jc.2014-3415
doi: 10.1210/jc.2014-3415
pubmed: 25590212
Di Lorenzo N, Antoniou SA, Batterham RL et al (2020) Clinical practice guidelines of the European Association for Endoscopic Surgery (EAES) on bariatric surgery: update 2020 endorsed by IFSO-EC, EASO and ESPCOP. Surg Endosc 34:2332–2358. https://doi.org/10.1007/s00464-020-07555-y
doi: 10.1007/s00464-020-07555-y
pubmed: 32328827
pmcid: 7214495
Donini LM, Cuzzolaro M, Spera G et al (2010) Obesity and eating disorders. indications for the different levels of care. An Italian Expert Consensus Document. Eat Weight Disord 15:1–31
pubmed: 20975326
Vigna L, Brunani A, Agnelli GM et al (2018) Defining the appropriate setting for treating obese patients: do we have the right tools? Eat Weight Disord 23:871–876. https://doi.org/10.1007/s40519-018-0595-x
doi: 10.1007/s40519-018-0595-x
pubmed: 30353452
Dalle Grave R, Melchionda N, Calugi S et al (2005) Continuous care in the treatment of obesity: an observational multicentre study. J Intern Med 258:265–273. https://doi.org/10.1111/j.1365-2796.2005.01524.x
doi: 10.1111/j.1365-2796.2005.01524.x
pubmed: 16115301
Bennett JA (2005) The Consolidated Standards of Reporting Trials (CONSORT): guidelines for reporting randomized trials. Nurs Res 54:128–132
doi: 10.1097/00006199-200503000-00007
Association AD, Bantle J, Wylie-Rosett J et al (2008) Nutrition recommendations and interventions for diabetes: a position statement of the American Diabetes Association. Diabetes Care 31:S61–S78. https://doi.org/10.2337/dc08-S061
doi: 10.2337/dc08-S061
Davis NJ, Emerenini A, Wylie-Rosett J (2006) Obesity management: physician practice patterns and patient preference. Diabetes Educ 32:557–561. https://doi.org/10.1177/0145721706290437
doi: 10.1177/0145721706290437
pubmed: 16873593
Wylie-Rosett J, Albright AA, Apovian C et al (2007) 2006–2007 American Diabetes Association Nutrition Recommendations: issues for practice translation. J Am Diet Assoc 107:1296–1304. https://doi.org/10.1016/j.jada.2007.05.009
doi: 10.1016/j.jada.2007.05.009
pubmed: 17659893
Norman AW (2008) From vitamin D to hormone D: fundamentals of the vitamin D endocrine system essential for good health. Am J Clin Nutr 88:491S–499S
doi: 10.1093/ajcn/88.2.491S
World Health Organization (2011) WHO Global recommendations on physical activity for health. World Health Organization, Geneva
Chlif M, Chaouachi A, Ahmaidi S (2017) Effect of aerobic exercise training on ventilatory efficiency and respiratory drive in obese subjects. Respir Care 62:936–946. https://doi.org/10.4187/respcare.04923
doi: 10.4187/respcare.04923
pubmed: 28442632
De Jong M, Spinhoven P, Korrelboom K et al (2020) Effectiveness of enhanced cognitive behavior therapy for eating disorders: A randomized controlled trial. Int J Eat Disord 53:447–457. https://doi.org/10.1002/eat.23239
doi: 10.1002/eat.23239
pubmed: 32040244
Haffner SM, Kennedy E, Gonzalez C et al (1996) A prospective analysis of the HOMA model. The Mexico City Diabetes Study. Diabetes Care 19:1138–1141. https://doi.org/10.2337/diacare.19.10.1138
doi: 10.2337/diacare.19.10.1138
pubmed: 8886564
Frisancho AR (1984) New standards of weight and body composition by frame size and height for assessment of nutritional status of adults and the elderly. Am J Clin Nutr 40:808–819. https://doi.org/10.1093/ajcn/40.4.808
doi: 10.1093/ajcn/40.4.808
pubmed: 6486088
Compher C, Frankenfield D, Keim N, Roth-Yousey L (2006) Best practice methods to apply to measurement of resting metabolic rate in adults: a systematic review. J Am Diet Assoc 106:881–903. https://doi.org/10.1016/j.jada.2006.02.009
doi: 10.1016/j.jada.2006.02.009
pubmed: 16720129
Weir JBDV (1949) New methods for calculating metabolic rate with special reference to protein metabolism. J Physiol 109:1–9. https://doi.org/10.1113/jphysiol.1949.sp004363
doi: 10.1113/jphysiol.1949.sp004363
pubmed: 15394301
pmcid: 1392602
Janssen I, Baumgartner RN, Ross R et al (2004) Skeletal muscle cutpoints associated with elevated physical disability risk in older men and women. Am J Epidemiol 159:413–421
doi: 10.1093/aje/kwh058
Mohammad A, De Lucia RE, Sleigh A et al (2017) Validity of visceral adiposity estimates from DXA against MRI in Kuwaiti men and women. Nutr Diabetes. https://doi.org/10.1038/nutd.2016.38
doi: 10.1038/nutd.2016.38
pubmed: 28067890
pmcid: 5301039
Baumgartner RN, Koehler KM, Gallagher D et al (1998) Epidemiology of sarcopenia among the elderly in New Mexico. Am J Epidemiol 147:755–763. https://doi.org/10.1093/oxfordjournals.aje.a009520
doi: 10.1093/oxfordjournals.aje.a009520
pubmed: 9554417
Kelly K, Kirschenbaum D (2011) Immersion treatment of childhood and adolescent obesity: the first review of a promising intervention. Obes Rev 12:37–49. https://doi.org/10.1111/J.1467-789X.2009.00710.X
doi: 10.1111/J.1467-789X.2009.00710.X
pubmed: 20070541
Capodaglio P, Cimolin V, Tacchini E et al (2013) Effectiveness of in-patient rehabilitation in obesity-related orthopedic conditions. J Endocrinol Invest 36:628–631
pubmed: 23511383
Maffiuletti NA, Agosti F, Marinone PG et al (2005) Changes in body composition, physical performance and cardiovascular risk factors after a 3-week integrated body weight reduction program and after 1-y follow-up in severely obese men and women. Eur J Clin Nutr 59:685–694. https://doi.org/10.1038/sj.ejcn.1602130
doi: 10.1038/sj.ejcn.1602130
pubmed: 15770221
Haslacher H, Fallmann H, Waldhäusl C et al (2019) Obesity: Outcome of standardized life-style change in a rehabilitation clinic. an observational study. Diabetes Metab Syndr Obes Targets Ther 12:813–820. https://doi.org/10.2147/DMSO.S197495
doi: 10.2147/DMSO.S197495
Tadokoro R, Iida T, Mikura K et al (2020) Factors involved in body weight loss and its maintenance in morbidly obese inpatients. Diabetol Int 11:41–48. https://doi.org/10.1007/s13340-019-00403-y
doi: 10.1007/s13340-019-00403-y
pubmed: 31950003
Weinreich T, Filz HP, Gresser U, Richartz BM (2017) Effectiveness of a four-week diet regimen, exercise and psychological intervention for weight loss. J Clin Diagnostic Res 11:LC20–LC24. https://doi.org/10.7860/JCDR/2017/24112.9553
doi: 10.7860/JCDR/2017/24112.9553
Buscemi S, Castellini G, Batsis JA et al (2013) Psychological and behavioural factors associated with long-term weight maintenance after a multidisciplinary treatment of uncomplicated obesity. Eat Weight Disord 18:351–358
doi: 10.1007/s40519-013-0059-2
Donini L, Savina C, Castellaneta E et al (2009) Multidisciplinary approach to obesity. Eat Weight Disord 14:23–32
doi: 10.1007/BF03327791
Donini LM, Cuzzolaro M, Gnessi L et al (2014) Obesity treatment: results after 4 years of a Nutritional and Psycho-Physical Rehabilitation Program in an outpatient setting. Eat Weight Disord 19:249–260
doi: 10.1007/s40519-014-0107-6
Perri M, Nezu A, Patti E, McCann K (1989) Effect of length of treatment on weight loss - PubMed. J Consult Clin Psychol 57:450–452
doi: 10.1037/0022-006X.57.3.450
Yamada T, Hara K, Svensson AK et al (2015) Successfully achieving target weight loss influences subsequent maintenance of lower weight and dropout from treatment. Obesity 23:183–191. https://doi.org/10.1002/oby.20874
doi: 10.1002/oby.20874
pubmed: 25324210