Zirconium Metal-Organic Polyhedra with Dual Behavior for Organophosphate Poisoning Treatment.
controlled drug delivery
host−guest chemistry
metal−organic cages
nerve agents
pesticide
Journal
ACS applied materials & interfaces
ISSN: 1944-8252
Titre abrégé: ACS Appl Mater Interfaces
Pays: United States
ID NLM: 101504991
Informations de publication
Date de publication:
02 Jun 2022
02 Jun 2022
Historique:
entrez:
2
6
2022
pubmed:
3
6
2022
medline:
3
6
2022
Statut:
aheadofprint
Résumé
Organophosphate nerve agents and pesticides are extremely toxic compounds because they result in acetylcholinesterase (AChE) inhibition and concomitant nerve system damage. Herein, we report the synthesis, structural characterization, and proof-of-concept utility of zirconium metal-organic polyhedra (Zr-MOPs) for organophosphate poisoning treatment. The results show the formation of robust tetrahedral cages [((
Identifiants
pubmed: 35653699
doi: 10.1021/acsami.2c06025
pmc: PMC9204697
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
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