Sexually transmitted doping: The impact of urine contamination of semen.


Journal

Drug testing and analysis
ISSN: 1942-7611
Titre abrégé: Drug Test Anal
Pays: England
ID NLM: 101483449

Informations de publication

Date de publication:
Sep 2022
Historique:
revised: 28 05 2022
received: 07 03 2022
accepted: 30 05 2022
pubmed: 4 6 2022
medline: 17 9 2022
entrez: 3 6 2022
Statut: ppublish

Résumé

The high sensitivity of antidoping detection tests creates the possibility of inadvertent doping due to an athlete's unknowing ingestion of contaminated environmental sources such as dietary supplements, food, or drinks. Recently, athletes denying use of a prohibited substance have claimed that the positive antidoping tests was due to exchange of bodily fluids with a nonathlete partner using a prohibited substance. Measurement of drugs in semen is largely limited to one or very few samples due to the inaccessibility of sufficiently frequent semen samples for detailed pharmacokinetics. An emerging issue in semen drug measurements is that semen samples may contain residual urine from ejaculation left in the urethra; however, the urine content in semen samples has not been studied. In the present study, we employed concurrent creatinine measurements in urine and seminal plasma to determine the urine content of semen samples.

Identifiants

pubmed: 35655428
doi: 10.1002/dta.3331
pmc: PMC9545268
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1623-1628

Informations de copyright

© 2022 Commonwealth of Australia. Drug Testing and Analysis published by John Wiley & Sons Ltd.

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Auteurs

David J Handelsman (DJ)

Andrology Department and Clinical Andrology Laboratory, Concord Hospital, Concord, NSW, Australia.
ANZAC Research Institute, University of Sydney, Concord, NSW, Australia.

Feyrous Bacha (F)

Andrology Department and Clinical Andrology Laboratory, Concord Hospital, Concord, NSW, Australia.

Marsha DeBono (M)

Diagnostic Pathology Unit, Concord Hospital, Concord, NSW, Australia.

Sue Sleiman (S)

Andrology Department and Clinical Andrology Laboratory, Concord Hospital, Concord, NSW, Australia.

Margaret R Janu (MR)

Diagnostic Pathology Unit, Concord Hospital, Concord, NSW, Australia.

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Classifications MeSH