Clinical and Pathological Features of Primary Renal Well-Differentiated Neuroendocrine Tumor.

pathological features renal well-differentiated neuroendocrine tumor

Journal

OncoTargets and therapy
ISSN: 1178-6930
Titre abrégé: Onco Targets Ther
Pays: New Zealand
ID NLM: 101514322

Informations de publication

Date de publication:
2022
Historique:
received: 01 03 2022
accepted: 23 05 2022
entrez: 3 6 2022
pubmed: 4 6 2022
medline: 4 6 2022
Statut: epublish

Résumé

Primary carcinoid tumor of the kidney is an extremely rare well-differentiated neuroendocrine tumor, which is generally a low-grade malignant cancer with a good prognosis. Carcinoid tumors are rarely found in the urinary system. Here, we report a 34-year-old woman with primary renal well-differentiated neuroendocrine tumor who underwent nephron sparing surgery and no evidence of recurrence or distant metastasis was found during routine follow-up. We searched the case of renal carcinoid with the search phrase "carcinoid [title] and kidney [title]" and "carcinoid [title] and renal [title]" using the PubMed and restricted the search to articles published in English since 2013. The clinical manifestations, age, sex, tumor size, location, gross pathology, light microscopy and immunohistochemistry were analyzed. A total of 28 cases of renal carcinoid were retrieved from PubMed. Higher proportion of positive labeling of CgA, Syn, NSE and CD56 are most valuable in the diagnosis of primary renal well-differentiated neuroendocrine tumor. At present, radical nephrectomy remains the gold standard in the curative-intent therapy for well-differentiated neuroendocrine carcinoma of kidney, in metastatic renal carcinoid, long-term use of octreotide may be an effective adjuvant therapy.

Identifiants

pubmed: 35655605
doi: 10.2147/OTT.S364545
pii: 364545
pmc: PMC9153994
doi:

Types de publication

Case Reports

Langues

eng

Pagination

587-596

Informations de copyright

© 2022 Jiang and Zhang.

Déclaration de conflit d'intérêts

The authors declare that they have no competing interests.

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Auteurs

Hua Jiang (H)

Department of Urology, The Fifth Affiliated Hospital of Zunyi Medical University (Zhuhai Sixth People's Hospital), Zhuhai, People's Republic of China.

He Zhang (H)

Department of Urology, The Fifth Affiliated Hospital of Zunyi Medical University (Zhuhai Sixth People's Hospital), Zhuhai, People's Republic of China.

Classifications MeSH