Molecular docking analysis of beta-caryophyllene with IRS-1, cSrc and Akt.
Akt
Beta-Caryophyllene
Diabetes mellitus
IRS-1
insulin resistance
molecular docking analysis
Journal
Bioinformation
ISSN: 0973-2063
Titre abrégé: Bioinformation
Pays: Singapore
ID NLM: 101258255
Informations de publication
Date de publication:
2021
2021
Historique:
received:
01
10
2021
revised:
18
10
2021
accepted:
18
10
2021
entrez:
3
6
2022
pubmed:
4
6
2022
medline:
4
6
2022
Statut:
epublish
Résumé
Diabetes mellitus (DM) is a common metabolic illness defined by hyperglycemia caused by insufficient production or absent of pancreatic insulin, with or without concomitant insulin action impairment. Hence, novel problem-solving approaches for assessing early metabolic diseases, notably insulin resistance, are urgently needed. Screening of natural compounds for drug discovery to combat diabetes is common in modern medical research and development. Therefore, it is of interest to document the molecular docking analysis data of beta-Caryophyllene, a naturally occurring sequiterpene with the downstream insulin signaling molecules such as IRS-1, cSrc and Akt for the management of type-2 diabetes. The molecular docking analysis data of beta-caryophyllene with the insulin downstream signaling molecules such as IRS-1, cSrc and Akt reveals its ability and further studies are needed to elucidate its complete mechanism of action against type-2 diabetes.
Identifiants
pubmed: 35655910
doi: 10.6026/97320630017916
pii: 97320630017916
pmc: PMC9148591
doi:
Types de publication
Journal Article
Langues
eng
Pagination
916-920Informations de copyright
© 2021 Biomedical Informatics.
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