Disparities in Access to Systemic Treatment for Breast Cancer in Thailand and Major Asian Territories.

Antineoplastic Agents Asians Breast Neoplasms Healthcare Disparity Thailand

Journal

Journal of breast cancer
ISSN: 1738-6756
Titre abrégé: J Breast Cancer
Pays: Korea (South)
ID NLM: 101314183

Informations de publication

Date de publication:
Jun 2022
Historique:
received: 25 02 2022
revised: 09 04 2022
accepted: 01 05 2022
pubmed: 4 6 2022
medline: 4 6 2022
entrez: 3 6 2022
Statut: ppublish

Résumé

Breast cancer (BC) treatment has shifted from chemotherapy to targeted therapy. Several targeted agents have demonstrated an improvement in survival. Given that national healthcare resources were correlated with the cancer mortality-to-incidence ratio, we compared access to BC drugs in Thailand with that in other Asian countries. BC experts involved in the Breast International Group (BIG)-Asia in six representative groups for countries or special administrative region (SAR) in Asia (Hong Kong SAR, Japan, Korea, Taiwan, Thailand, and Singapore) were invited to participate in the survey. The questionnaire addressed national health reimbursement schemes, molecular testing for early BC (EBC), availability and accessibility of BC drugs. Accessibility and reimbursement of the drugs were reported based on their listing as essential medicines in the World Health Organization Model List of Essential Medicines (WHO-EML) and their nomination as effective drugs in the European Society for Medical Oncology-Magnitude of Clinical Benefit Scale (ESMO-MCBS). The study was approved by all participating BIG-Asia organizations in November 2021. Genomic tests for EBC were non-reimbursable in all surveyed territories. Reimbursement and co-payment of BC drugs vary between and within these regions (particularly Thailand). Most drugs in the WHO-EML and ESMO-MCBS (A/B for EBC and 4/5 for advanced BC) were accessible in all surveyed territories. However, the accessibility of effective but costly WHO-EML and ESMO-MCBS drugs was not uniform in Thailand. There was an evident disparity for individuals covered by the Thai Social Security/Universal Health Coverage schemes. Essential BC drugs are generally accessible in selected BIG-Asia countries or SAR. There is a disparity in accessing high-cost drugs in Thailand compared with other Asian territories.

Identifiants

pubmed: 35657002
pii: 25.e21
doi: 10.4048/jbc.2022.25.e21
pmc: PMC9250880
doi:

Types de publication

Journal Article

Langues

eng

Pagination

207-217

Informations de copyright

© 2022 Korean Breast Cancer Society.

Déclaration de conflit d'intérêts

SI received an honorarium from Novartis.

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Auteurs

Suthinee Ithimakin (S)

Division of Medical Oncology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.

Napa Parinyanitikul (N)

Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.

Sung-Bae Kim (SB)

Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

Yoon-Sim Yap (YS)

Division of Medical Oncology, National Cancer Centre Singapore, Singapore.

Janice Tsang (J)

Department of Medicine, and Medical Ethics & Humanities unit, The University of Hong Kong, Hong Kong.

Inda S Soong (IS)

Department of Clinical Oncology, Pamela Youde Nethersole Eastern Hospital, Hospital Authority, Hong Kong.

Yukinori Ozaki (Y)

Department of Breast Medical Oncology, The Cancer Institute Hospital of Japanese Foundation for Cancer Research, Tokyo, Japan.

Shinji Ohno (S)

Breast Oncology Center, The Cancer Institute Hospital of Japanese Foundation for Cancer Research, Tokyo, Japan.

Makiko Ono (M)

Department of Medical Oncology, The Cancer Institute Hospital of Japanese Foundation for Cancer Research, Tokyo, Japan.

Jack Junjie Chan (JJ)

Division of Medical Oncology, National Cancer Centre Singapore, Singapore.

Hung Chun Skye Cheng (HCS)

Department of Radiation Oncology, Koo Foundation Sun Yat-Sen Cancer Center, Taipei, Taiwan.
Taitung Cancer Center, Taitung Christian Hospital, Taitung City, Taiwan.

Thitiya Dejthevaporn (T)

Medical Oncology Unit, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand. tsirisinha@yahoo.com.

Classifications MeSH