Neonatal Glucose Homeostasis.

Hypoglycemia is a common condition in the newborn period. Several intrinsic and extrinsic factors play a role in the degree/duration of hypoglycemia. Multiple thresholds have been proposed as a potential point whereby hypoglycemia may have short and long-term adverse effects. Rather than a "numerical" threshold, treatment approaches should be individualized and tailored to the etiology, symptoms, and neonatal underlying conditions. Hyperglycemia in the newborn period is commonly seen in preterm infants and can exert gluco-toxic effects in organs at critical periods of development. Considering the peripheral insulin resistance (IR) of prematurity and contributing factors is key to achieving euglycemia.

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Déclaration de conflit d'intérêts

Disclosure Dr C.L. Blanco has received federal and nonfederal funding for glucose metabolism studies. All data utilized in this review have been published and funding sources are detailed in each article referenced.