Frailty prevalence and impact on outcomes in patients with atrial fibrillation: A systematic review and meta-analysis of 1,187,000 patients.

Anticoagulants Atrial Fibrillation / epidemiology Frailty / epidemiology Humans Prevalence Risk Factors Stroke / etiology
Atrial fibrillation Epidemiology Frailty Mortality Stroke

Journal

Ageing research reviews
ISSN: 1872-9649
Titre abrégé: Ageing Res Rev
Pays: England
ID NLM: 101128963

Informations de publication

Date de publication:
08 2022
Historique:
received: 26 02 2022
revised: 20 04 2022
accepted: 23 05 2022
pubmed: 7 6 2022
medline: 19 7 2022
entrez: 6 6 2022
Statut: ppublish

Résumé

Frailty is a clinical syndrome characterized by a reduced physiologic reserve, increased vulnerability to stressors and an increased risk of adverse outcomes. People with atrial fibrillation (AF) are often burdened by frailty due to biological, clinical, and social factors. The prevalence of frailty, its management and association with major outcomes in AF patients are still not well quantified. We systematically searched PubMed and EMBASE, from inception to September 13th, 2021, for studies reporting the prevalence of frailty in AF patients. The study was registered in PROSPERO (CRD42021235854). 33 studies were included in the systematic review (n = 1,187,651 patients). The frailty pooled prevalence was 39.7 % (95 %CI=29.9 %-50.5 %, I

Identifiants

DOI: 10.1016/j.arr.2022.101652 PMID: 35659945
pubmed: 35659945
pii: S1568-1637(22)00094-0
doi: 10.1016/j.arr.2022.101652
pii:
doi:

Substances chimiques

Anticoagulants 0

Types de publication

Journal Article Meta-Analysis Review Systematic Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

101652

Informations de copyright

Copyright © 2022 Elsevier B.V. All rights reserved.

Auteurs

Marco Proietti (M)

Geriatric Unit, IRCCS Istituti Clinici Scientifici Maugeri, Milan, Italy; Department of Clinical Sciences and Community Health, University of Milan, Italy; Liverpool Centre for Cardiovascular Science, University of Liverpool and Liverpool Heart & Chest Hospital, Liverpool, United Kingdom. Electronic address: marco.proietti@unimi.it.

Giulio Francesco Romiti (GF)

Department of Translational and Precision Medicine, Sapienza University of Rome, Italy.

Valeria Raparelli (V)

Department of Translational Medicine, University of Ferrara, Italy; University Center for Studies on Gender Medicine, University of Ferrara, Italy; University of Alberta, Faculty of Nursing, Edmonton, Alberta, Canada.

Igor Diemberger (I)

Department of Experimental, Diagnostic and Specialty Medicine, Institute of Cardiology, University of Bologna, Policlinico S. Orsola-Malpighi, Bologna, Italy.

Giuseppe Boriani (G)

Cardiology Division, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Policlinico di Modena, Italy.

Laura Adelaide Dalla Vecchia (LA)

Department of Cardiology, IRCCS Istituti Clinici Scientifici Maugeri, Milan, Italy.

Giuseppe Bellelli (G)

School of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy; Acute Geriatrics Unit, San Gerardo Hospital ASST Monza, Monza, Italy.

Emanuele Marzetti (E)

Università Cattolica del Sacro Cuore, Department of Geriatrics and Orthopedics, Rome, Italy; Center for Geriatric Medicine (Ce.M.I.), Fondazione Policlinico Universitario "Agostino Gemelli" IRCCS, Rome,Italy.

Gregory Yh Lip (GY)

Liverpool Centre for Cardiovascular Science, University of Liverpool and Liverpool Heart & Chest Hospital, Liverpool, United Kingdom; Department of Clinical Medicine, Aalborg University, Aalborg, Denmark.

Matteo Cesari (M)

Geriatric Unit, IRCCS Istituti Clinici Scientifici Maugeri, Milan, Italy; Department of Clinical Sciences and Community Health, University of Milan, Italy.

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Classifications MeSH

questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Agents hématologiques › Anticoagulants › Frailty prevalence and impact on outcomes in...
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Troubles du rythme cardiaque › Fibrillation auriculaire › Frailty prevalence and impact on outcomes in...
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Fragilité › Frailty prevalence and impact on outcomes in...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Frailty prevalence and impact on outcomes in...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Collecte de données › Registre civil › Morbidité › Prévalence › Frailty prevalence and impact on outcomes in...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Statistiques comme sujet › Probabilité › Risque › Facteurs de risque › Frailty prevalence and impact on outcomes in...
questionsmedicales.fr › Maladies cardiovasculaires › Maladies vasculaires › Angiopathies intracrâniennes › Accident vasculaire cérébral › Frailty prevalence and impact on outcomes in...