Effect of exercise on functional capacity in patients with advanced cancer: A meta-analysis of randomized controlled trials.

Exercise Exercise Therapy Humans Neoplasms / therapy Quality of Life Randomized Controlled Trials as Topic
Advanced cancer Exercise Functional capacity Physical intervention Six minutes, walking test

Journal

Critical reviews in oncology/hematology
ISSN: 1879-0461
Titre abrégé: Crit Rev Oncol Hematol
Pays: Netherlands
ID NLM: 8916049

Informations de publication

Date de publication:
Jul 2022
Historique:
received: 11 05 2022
revised: 19 05 2022
accepted: 19 05 2022
pubmed: 7 6 2022
medline: 22 6 2022
entrez: 6 6 2022
Statut: ppublish

Résumé

To determine the impact of exercise on functional capacity, measured through the "Six minutes walking test" (6MWT) in patients with advanced cancer stage. Systematic research on PubMed, Cochrane Library, and SportDiscus was conducted. Randomized controlled trials were eligible if they examined the effect of exercise on 6MWT. Overall, a total of ten trials were included in the primary analysis. Compared to the controls, the exercise intervention was associated with an increase in functional capacity (+20.86 m; CI: -5.90 to 47.72, p = 0.12) although not reaching the statistical significance. Sensitivity analysis revealed an improvement for studies proposing a supervised exercise intervention towards the statistical significance. Few adverse events were associated with exercise training, and the median withdrawals rate was 17%. Exercise may have a beneficial role on functional capacity in patients with advanced cancer, especially if supervised.

Identifiants

DOI: 10.1016/j.critrevonc.2022.103726 PMID: 35659975
pubmed: 35659975
pii: S1040-8428(22)00150-0
doi: 10.1016/j.critrevonc.2022.103726
pii:
doi:

Types de publication

Journal Article Meta-Analysis

Langues

eng

Sous-ensembles de citation

IM

Pagination

103726

Informations de copyright

Copyright © 2022 Elsevier B.V. All rights reserved.

Auteurs

Alice Avancini (A)

Section of Oncology, Department of Medicine, University of Verona School of Medicine and Verona University Hospital Trust, Verona, Italy; Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy. Electronic address: alice.avancini@univr.it.

Isabella Sperduti (I)

Biostatistical Unit - Clinical Trials Center IRCCS Istituto Nazionale Tumori Regina Elena, U.O. di Biostatistica e Bioinformatica, Rome, Italy. Electronic address: isabella.sperduti@ifo.it.

Anita Borsati (A)

Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy. Electronic address: anita.borsati02@univr.it.

Thomas Ferri (T)

Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy. Electronic address: ferrithomas@icloud.com.

Lorenzo Belluomini (L)

Section of Oncology, Department of Medicine, University of Verona School of Medicine and Verona University Hospital Trust, Verona, Italy. Electronic address: lorenzo.belluomini@univr.it.

Jessica Insolda (J)

Section of Oncology, Department of Medicine, University of Verona School of Medicine and Verona University Hospital Trust, Verona, Italy. Electronic address: jessica.insolda@aovr.veneto.it.

Ilaria Trestini (I)

Section of Oncology, Department of Medicine, University of Verona School of Medicine and Verona University Hospital Trust, Verona, Italy. Electronic address: ilariatrestini92@gmail.com.

Daniela Tregnago (D)

Section of Oncology, Department of Medicine, University of Verona School of Medicine and Verona University Hospital Trust, Verona, Italy. Electronic address: daniela.tregnago2@aovr.veneto.it.

Federico Schena (F)

Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy. Electronic address: federico.schena@univr.it.

Emilio Bria (E)

Department of Medical Oncology, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy. Electronic address: emilio.bria@unicatt.it.

Michele Milella (M)

Section of Oncology, Department of Medicine, University of Verona School of Medicine and Verona University Hospital Trust, Verona, Italy. Electronic address: michele.milella@univr.it.

Sara Pilotto (S)

Section of Oncology, Department of Medicine, University of Verona School of Medicine and Verona University Hospital Trust, Verona, Italy. Electronic address: sara.pilotto@univr.it.

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Classifications MeSH

questionsmedicales.fr › Activités humaines › Exercice physique › Effect of exercise on functional capacity in...
questionsmedicales.fr › Thérapeutique › Techniques de physiothérapie › Traitement par les exercices physiques › Effect of exercise on functional capacity in...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Effect of exercise on functional capacity in...
questionsmedicales.fr › Tumeurs › Effect of exercise on functional capacity in...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Mesures épidémiologiques › Démographie › État de santé › Qualité de vie › Effect of exercise on functional capacity in...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Caractéristiques des études épidémiologiques › Études cliniques comme sujet › Essais cliniques comme sujet › Essais cliniques contrôlés comme sujet › Essais contrôlés randomisés comme sujet › Effect of exercise on functional capacity in...