Mobile footprinting: linking individual distinctiveness in mobility patterns to mood, sleep, and brain functional connectivity.
Journal
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology
ISSN: 1740-634X
Titre abrégé: Neuropsychopharmacology
Pays: England
ID NLM: 8904907
Informations de publication
Date de publication:
08 2022
08 2022
Historique:
received:
14
10
2021
accepted:
23
05
2022
revised:
18
05
2022
pubmed:
7
6
2022
medline:
19
7
2022
entrez:
6
6
2022
Statut:
ppublish
Résumé
Mapping individual differences in behavior is fundamental to personalized neuroscience, but quantifying complex behavior in real world settings remains a challenge. While mobility patterns captured by smartphones have increasingly been linked to a range of psychiatric symptoms, existing research has not specifically examined whether individuals have person-specific mobility patterns. We collected over 3000 days of mobility data from a sample of 41 adolescents and young adults (age 17-30 years, 28 female) with affective instability. We extracted summary mobility metrics from GPS and accelerometer data and used their covariance structures to identify individuals and calculated the individual identification accuracy-i.e., their "footprint distinctiveness". We found that statistical patterns of smartphone-based mobility features represented unique "footprints" that allow individual identification (p < 0.001). Critically, mobility footprints exhibited varying levels of person-specific distinctiveness (4-99%), which was associated with age and sex. Furthermore, reduced individual footprint distinctiveness was associated with instability in affect (p < 0.05) and circadian patterns (p < 0.05) as measured by environmental momentary assessment. Finally, brain functional connectivity, especially those in the somatomotor network, was linked to individual differences in mobility patterns (p < 0.05). Together, these results suggest that real-world mobility patterns may provide individual-specific signatures relevant for studies of development, sleep, and psychopathology.
Identifiants
pubmed: 35660803
doi: 10.1038/s41386-022-01351-z
pii: 10.1038/s41386-022-01351-z
pmc: PMC9163291
doi:
Types de publication
Journal Article
Research Support, N.I.H., Intramural
Research Support, Non-U.S. Gov't
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Pagination
1662-1671Subventions
Organisme : NIMH NIH HHS
ID : R01 MH112847
Pays : United States
Organisme : NIBIB NIH HHS
ID : R01 EB022573
Pays : United States
Organisme : NIMH NIH HHS
ID : R01 MH120482
Pays : United States
Organisme : NIMH NIH HHS
ID : R01 MH113550
Pays : United States
Organisme : NIDA NIH HHS
ID : K01 DA047417
Pays : United States
Organisme : NIMH NIH HHS
ID : RF1 MH116920
Pays : United States
Organisme : NIMH NIH HHS
ID : R37 MH125829
Pays : United States
Organisme : NIH HHS
ID : S10 OD023495
Pays : United States
Organisme : NIMH NIH HHS
ID : R01 MH107703
Pays : United States
Organisme : NIMH NIH HHS
ID : R01 MH116884
Pays : United States
Informations de copyright
© 2022. The Author(s), under exclusive licence to American College of Neuropsychopharmacology.
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