International Perspectives on Joint Hypermobility: A Synthesis of Current Science to Guide Clinical and Research Directions.


Journal

Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases
ISSN: 1536-7355
Titre abrégé: J Clin Rheumatol
Pays: United States
ID NLM: 9518034

Informations de publication

Date de publication:
01 Sep 2022
Historique:
pubmed: 7 6 2022
medline: 31 8 2022
entrez: 6 6 2022
Statut: ppublish

Résumé

There is exponential clinical and research interest in joint hypermobility due to recognition of the complexity of identification, assessment, and its appropriate referral pathways, ultimately impacting management. This state-of-the-science review provides an international, multidisciplinary perspective on the presentation, etiology, and assessment of joint hypermobility, as it presents in those with and without a systemic condition. We synthesize the literature, propose standardizing the use of terminology and outcome measures, and suggest potential management directions. The major topics covered are (i) historical perspectives; (ii) current definitions of hypermobility, laxity, and instability; (iii) inheritance and acquisition of hypermobility; (iv) traditional and novel assessments; (v) strengths and limitations of current assessment tools; (vi) age, sex, and racial considerations; (vii) phenotypic presentations; (viii) generalized hypermobility spectrum disorder and hypermobility Ehlers-Danlos syndrome; and (ix) clinical implications and research directions. A thorough understanding of these topics will equip the reader seeking to manage individuals presenting with joint hypermobility, while mindful of its etiology. Management of generalized joint hypermobility in the context of a complex, multisystem condition will differ from that of acquired hypermobility commonly seen in performing artists, specific athletic populations, posttrauma, and so on. In addition, people with symptomatic hypermobility present predominantly with musculoskeletal symptoms and sometimes systemic symptoms including fatigue, orthostatic intolerance, and gastrointestinal or genitourinary issues. Some also display skeletal deformities, tissue and skin fragility, and structural vascular or cardiac differences, and these warrant further medical follow-up. This comprehensive review on the full spectrum of joint hypermobility will assist clinicians, coaches/sports trainers, educators, and/or researchers in this area.

Identifiants

pubmed: 35661088
doi: 10.1097/RHU.0000000000001864
pii: 00124743-202209000-00005
pmc: PMC9422750
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

314-320

Informations de copyright

Copyright © 2022 The Author(s). Published by Wolters Kluwer Health, Inc.

Déclaration de conflit d'intérêts

The authors declare no conflict of interest.

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Auteurs

Leslie L Nicholson (LL)

From the School of Medical Sciences, Faculty of Medicine & Health, The University of Sydney, Sydney, New South Wales, Australia.

Jane Simmonds (J)

Great Ormond Street Institute of Child Health, University College London, London, United Kingdom.

Verity Pacey (V)

Department of Health Sciences, Faculty of Medicine, Health & Human Sciences, Macquarie University, Sydney, New South Wales, Australia.

Inge De Wandele (I)

Center for Medical Genetics, Ghent University Hospital/Ghent University, Ghent, Belgium.

Lies Rombaut (L)

Center for Medical Genetics, Ghent University Hospital/Ghent University, Ghent, Belgium.

Cylie M Williams (CM)

School of Primary and Allied Health Care, The University of Melbourne, Melbourne, Victoria, Australia.

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