Fibroblast growth factor homologous factors serve as a molecular rheostat in tuning arrhythmogenic cardiac late sodium current.
Journal
Nature cardiovascular research
ISSN: 2731-0590
Titre abrégé: Nat Cardiovasc Res
Pays: England
ID NLM: 9918284280206676
Informations de publication
Date de publication:
May 2022
May 2022
Historique:
entrez:
6
6
2022
pubmed:
7
6
2022
medline:
7
6
2022
Statut:
ppublish
Résumé
Voltage-gated sodium (Nav1.5) channels support the genesis and brisk spatial propagation of action potentials in the heart. Disruption of Na
Identifiants
pubmed: 35662881
doi: 10.1038/s44161-022-00060-6
pmc: PMC9161660
mid: NIHMS1795701
doi:
Types de publication
Journal Article
Langues
eng
Pagination
1-13Subventions
Organisme : NHLBI NIH HHS
ID : R01 HL160089
Pays : United States
Organisme : NHLBI NIH HHS
ID : T32 HL120826
Pays : United States
Organisme : NINDS NIH HHS
ID : R01 NS110672
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL128743
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL140934
Pays : United States
Déclaration de conflit d'intérêts
Competing Interests N.C., S.O.M, and M.B.-J., (inventors) filed a provisional patent (attorney docket no. CoU1046P/CU22077; filed 14 February 2022) for application of FixR for inhibiting late Na current. The remaining authors declare no competing interests.
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