Trauma Disrupts Reinforcement Learning in Rats-A Novel Animal Model of Chronic Stress Exposure.

PTSD chronic stress predator odor reinforcement learning trauma

Journal

Frontiers in behavioral neuroscience
ISSN: 1662-5153
Titre abrégé: Front Behav Neurosci
Pays: Switzerland
ID NLM: 101477952

Informations de publication

Date de publication:
2022
Historique:
received: 23 03 2022
accepted: 25 04 2022
entrez: 6 6 2022
pubmed: 7 6 2022
medline: 7 6 2022
Statut: epublish

Résumé

Trauma, as well as chronic stress that characterizes a modern fast-paced lifestyle, contributes to numerous psychopathologies and psychological problems. Psychiatric patients with traumas, as well as healthy individuals who experienced traumas in the past, are often characterized by diminished cognitive abilities. In our protocol, we used an animal model to explore the influence of chronic trauma on cognitive abilities and behavior in the group of 20 rats (Rattus norvegicus). The experimental group was introduced to chronic (12 consecutive days) exposure to predator odor (bobcat urine). We measured the reinforcement learning of each individual before and after the exposition

Identifiants

pubmed: 35663358
doi: 10.3389/fnbeh.2022.903100
pmc: PMC9157238
doi:

Types de publication

Journal Article

Langues

eng

Pagination

903100

Informations de copyright

Copyright © 2022 Bielawski, Drapała, Krowicki, Stańczykiewicz and Frydecka.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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Auteurs

Tomasz Bielawski (T)

Department of Psychiatry, Wrocław Medical University, Wrocław, Poland.

Jarosław Drapała (J)

Department of Computer Science and Systems Engineering, Faculty of Information and Communication Technology, Wrocław University of Science and Technology, Wrocław, Poland.

Paweł Krowicki (P)

Department of Laser Technologies, Automation and Production Management, Faculty of Mechanical Engineering, Wrocław University of Science and Technology, Wrocław, Poland.

Bartłomiej Stańczykiewicz (B)

Department of Psychiatry, Wrocław Medical University, Wrocław, Poland.

Dorota Frydecka (D)

Department of Psychiatry, Wrocław Medical University, Wrocław, Poland.

Classifications MeSH