Clinical whole exome sequencing revealed

DNA, Deoxyribonucleic acid Developmental and Epileptic Encephalopathy 4 EEG, Electroencephalogram Heterozygous MRI, Magnetic Resonance Imaging STXBP1 STXBP1, Syntaxin-binding protein 1 Saudi Arabia Stop-Gain Mutation WES, Whole exom sequencing

Journal

Saudi journal of biological sciences
ISSN: 1319-562X
Titre abrégé: Saudi J Biol Sci
Pays: Saudi Arabia
ID NLM: 101543796

Informations de publication

Date de publication:
Jul 2022
Historique:
received: 08 02 2022
revised: 06 03 2022
accepted: 15 05 2022
entrez: 6 6 2022
pubmed: 7 6 2022
medline: 7 6 2022
Statut: ppublish

Résumé

Intellectual disability and developmental encephalopathies are mostly linked with infant epilepsy. Epileptic encephalopathy is a term that is used to define association between developmental delay and epilepsy. Mutations in the

Identifiants

pubmed: 35663845
doi: 10.1016/j.sjbs.2022.103309
pii: S1319-562X(22)00225-X
pmc: PMC9160351
doi:

Types de publication

Journal Article

Langues

eng

Pagination

103309

Informations de copyright

© 2022 The Author(s).

Déclaration de conflit d'intérêts

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Références

Brain Sci. 2021 Sep 29;11(10):
pubmed: 34679360
Epilepsia. 2011 Oct;52(10):1820-7
pubmed: 21762454
Epilepsy Behav. 2019 Mar;92:121-124
pubmed: 30654231
Neurogenetics. 2015 Jan;16(1):65-7
pubmed: 25418441
Nature. 1993 Nov 25;366(6453):347-51
pubmed: 8247129
Semin Fetal Neonatal Med. 2018 Jun;23(3):204-212
pubmed: 29426806
Front Genet. 2020 Feb 21;11:14
pubmed: 32153630
Epilepsia. 2016 Mar;57(3):343-7
pubmed: 26778176
Epilepsia. 2020 Apr;61(4):810-821
pubmed: 32112430
Neurology. 2016 Mar 8;86(10):954-62
pubmed: 26865513
Seizure. 2018 Aug;60:68-70
pubmed: 29929108
Cell Rep. 2014 Oct 9;9(1):206-218
pubmed: 25284778
Neurology. 2019 Jul 16;93(3):114-123
pubmed: 31221716
Clin Genet. 2012 Apr;81(4):399-402
pubmed: 22211739
Ann Neurol. 2009 Jun;65(6):748-53
pubmed: 19557857
Curr Opin Neurol. 2020 Apr;33(2):179-184
pubmed: 32049741
Biomed Res Int. 2019 Dec 17;2019:4872101
pubmed: 31976320
Expert Opin Ther Targets. 2017 Nov;21(11):1027-1036
pubmed: 28971703
Epilepsia. 2010 Dec;51(12):2449-52
pubmed: 21204804
Front Pediatr. 2021 Feb 11;8:627122
pubmed: 33643967
J Neurosci. 2017 Sep 6;37(36):8797-8815
pubmed: 28821673
J Neurochem. 2021 Apr;157(2):165-178
pubmed: 32643187
Brain. 2018 May 1;141(5):1350-1374
pubmed: 29538625
J Cell Biol. 2016 Sep 12;214(6):705-18
pubmed: 27597756
J Biol Chem. 2014 Apr 4;289(14):9639-50
pubmed: 24532794
Epilepsia. 2011 Oct;52(10):1828-34
pubmed: 21770924
Neurology. 2010 Sep 28;75(13):1159-65
pubmed: 20876469
Nat Genet. 2008 Jun;40(6):782-8
pubmed: 18469812
J Neurosci. 2016 Jun 29;36(26):6881-91
pubmed: 27358447
Epilepsia. 2010 Apr;51(4):676-85
pubmed: 20196795
Epilepsia. 2015 Dec;56(12):1931-40
pubmed: 26514728
Neurology. 2014 Apr 8;82(14):1245-53
pubmed: 24623842
Eur J Epidemiol. 2005;20(12):1003-5
pubmed: 16331431
Genet Med. 2012 Oct;14(10):868-76
pubmed: 22722545
Nat Commun. 2018 Sep 28;9(1):3986
pubmed: 30266908
J Child Neurol. 2012 Jun;27(6):811-4
pubmed: 22596016
Elife. 2020 Feb 19;9:
pubmed: 32073399

Auteurs

Muhammad Imran Naseer (MI)

Center of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, Saudi Arabia.
Department of Medical Laboratory Technology, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, Saudi Arabia.

Angham Abdulrhman Abdulkareem (AA)

Center of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, Saudi Arabia.
Faculty of Science, Department of Biochemistry, King Abdulaziz University, Jeddah, Saudi Arabia.

Mahmood Rasool (M)

Center of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, Saudi Arabia.
Department of Medical Laboratory Technology, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, Saudi Arabia.

Bader Shirah (B)

Department of Neuroscience, King Faisal Specialist Hospital & Research Centre, Jeddah, Saudi Arabia.

Hussein Algahtani (H)

King Abdulaziz Medical City, King Saud Bin Abdulaziz University for Health Sciences, Jeddah, Saudi Arabia.

Osama Y Muthaffar (OY)

Department of Pediatrics, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.

Peter Natesan Pushparaj (PN)

Center of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, Saudi Arabia.
Department of Medical Laboratory Technology, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, Saudi Arabia.

Classifications MeSH