Loss of speech and functional impairment in Alzheimer's disease-related primary progressive aphasia: predictive factors of decline.

Alzheimer Disease / diagnostic imaging Amyloid beta-Peptides / metabolism Aphasia, Primary Progressive / diagnosis Biomarkers / metabolism Brain / diagnostic imaging Fluorodeoxyglucose F18 / metabolism Humans Positron-Emission Tomography Speech tau Proteins / metabolism
Alzheimer's disease Amyloid biomarkers Brain metabolism Disease progression Neuropsychology Primary progressive aphasia

Journal

Neurobiology of aging
ISSN: 1558-1497
Titre abrégé: Neurobiol Aging
Pays: United States
ID NLM: 8100437

Informations de publication

Date de publication:
09 2022
Historique:
received: 17 09 2021
revised: 11 04 2022
accepted: 04 05 2022
pubmed: 7 6 2022
medline: 20 7 2022
entrez: 6 6 2022
Statut: ppublish

Résumé

We aimed to identify features associated with different disease trajectories in Alzheimer's disease (AD)-related primary progressive aphasia (PPA). We considered 23 patients diagnosed with AD-related PPA. All patients underwent neuropsychological evaluation,

Identifiants

DOI: 10.1016/j.neurobiolaging.2022.05.002 PMID: 35665686
pubmed: 35665686
pii: S0197-4580(22)00108-7
doi: 10.1016/j.neurobiolaging.2022.05.002
pii:
doi:

Substances chimiques

Amyloid beta-Peptides 0
Biomarkers 0
tau Proteins 0
Fluorodeoxyglucose F18 0Z5B2CJX4D

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

59-70

Informations de copyright

Copyright © 2022 Elsevier Inc. All rights reserved.

Auteurs

Salvatore Mazzeo (S)

Department of Neuroscience, Psychology, Drug Research and Child Health, University of Florence, Azienda Ospedaliera-Universitaria Careggi, Florence, Italy; IRCCS Fondazione Don Carlo Gnocchi, Florence, Italy.

Cristina Polito (C)

IRCCS Fondazione Don Carlo Gnocchi, Florence, Italy.

Michael Lassi (M)

The BioRobotics Institute, Scuola Superiore Sant'Anna, Pisa, Italy; Department of Excellence in Robotics and AI, Scuola Superiore Sant'Anna, Pisa, Italy.

Silvia Bagnoli (S)

Department of Neuroscience, Psychology, Drug Research and Child Health, University of Florence, Azienda Ospedaliera-Universitaria Careggi, Florence, Italy.

Marta Mattei (M)

Department of Neuroscience, Psychology, Drug Research and Child Health, University of Florence, Azienda Ospedaliera-Universitaria Careggi, Florence, Italy.

Sonia Padiglioni (S)

Regional Referral Centre for Relational Criticalities, Tuscany Region, Italy; Unit Clinic of Organizations, Azienda Ospedaliera-Universitaria Careggi, Florence, Italy.

Valentina Berti (V)

Department of Biomedical, Experimental and Clinical Sciences "Mario Serio", University of Florence, Florence, Italy; Nuclear Medicine Unit, Azienda Ospedaliero-Universitaria Careggi, Florence, Italy.

Gemma Lombardi (G)

IRCCS Fondazione Don Carlo Gnocchi, Florence, Italy.

Giulia Giacomucci (G)

Department of Neuroscience, Psychology, Drug Research and Child Health, University of Florence, Azienda Ospedaliera-Universitaria Careggi, Florence, Italy.

Maria Teresa De Cristofaro (MT)

Nuclear Medicine Unit, Azienda Ospedaliero-Universitaria Careggi, Florence, Italy.

Alessandro Passeri (A)

Department of Biomedical, Experimental and Clinical Sciences "Mario Serio", University of Florence, Florence, Italy.

Camilla Ferrari (C)

Department of Neuroscience, Psychology, Drug Research and Child Health, University of Florence, Azienda Ospedaliera-Universitaria Careggi, Florence, Italy.

Benedetta Nacmias (B)

Department of Neuroscience, Psychology, Drug Research and Child Health, University of Florence, Azienda Ospedaliera-Universitaria Careggi, Florence, Italy; IRCCS Fondazione Don Carlo Gnocchi, Florence, Italy.

Alberto Mazzoni (A)

The BioRobotics Institute, Scuola Superiore Sant'Anna, Pisa, Italy; Department of Excellence in Robotics and AI, Scuola Superiore Sant'Anna, Pisa, Italy.

Sandro Sorbi (S)

Department of Neuroscience, Psychology, Drug Research and Child Health, University of Florence, Azienda Ospedaliera-Universitaria Careggi, Florence, Italy; IRCCS Fondazione Don Carlo Gnocchi, Florence, Italy.

Valentina Bessi (V)

Department of Neuroscience, Psychology, Drug Research and Child Health, University of Florence, Azienda Ospedaliera-Universitaria Careggi, Florence, Italy. Electronic address: valentina.bessi@unifi.it.

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Classifications MeSH

questionsmedicales.fr › Troubles mentaux › Troubles neurocognitifs › Démence › Maladie d'Alzheimer › Loss of speech and functional impairment in...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Peptides bêta-amyloïdes › Loss of speech and functional impairment in...
questionsmedicales.fr › Troubles mentaux › Troubles neurocognitifs › Démence › Aphasie progressive primaire › Loss of speech and functional impairment in...
questionsmedicales.fr › Facteurs biologiques › Marqueurs biologiques › Loss of speech and functional impairment in...
questionsmedicales.fr › Système nerveux › Système nerveux central › Encéphale › Loss of speech and functional impairment in...
questionsmedicales.fr › Glucides › Désoses › Désoxyglucose › Fluorodésoxyglucose F18 › Loss of speech and functional impairment in...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Loss of speech and functional impairment in...
questionsmedicales.fr › Diagnostic › Techniques et procédures diagnostiques › Techniques de diagnostic radioisotopique › Scintigraphie › Tomoscintigraphie › Tomographie par émission de positons › Loss of speech and functional impairment in...
questionsmedicales.fr › Sciences de l'information › Langage › Arts du langage › Parole › Loss of speech and functional impairment in...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines de tissu nerveux › Protéines associées aux microtubules › Protéines tau › Loss of speech and functional impairment in...