Affinity of aromatic amino acid side chains in amino acid solvents.
Amino acid interaction
Amino acid side chain
Hydrophobicity
Protein condensate
Solubility
Journal
Biophysical chemistry
ISSN: 1873-4200
Titre abrégé: Biophys Chem
Pays: Netherlands
ID NLM: 0403171
Informations de publication
Date de publication:
08 2022
08 2022
Historique:
received:
20
03
2022
revised:
21
05
2022
accepted:
22
05
2022
pubmed:
7
6
2022
medline:
18
6
2022
entrez:
6
6
2022
Statut:
ppublish
Résumé
The affinity between amino acid and water is important for understanding how proteins behave in aqueous solutions. For example, the hydrophobicity of amino acid side chains determines a protein's solubility. However, the affinity of amino acid side chains in amino acid solvents should be determined in order to understand the propensity of protein condensates induced by multivalent amino acid interactions. Here we measured the transfer free energy of amino acid side chains (ΔG
Identifiants
pubmed: 35667130
pii: S0301-4622(22)00073-4
doi: 10.1016/j.bpc.2022.106831
pii:
doi:
Substances chimiques
Amino Acids
0
Amino Acids, Aromatic
0
Proteins
0
Solvents
0
Water
059QF0KO0R
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
106831Informations de copyright
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