Affinity of aromatic amino acid side chains in amino acid solvents.


Journal

Biophysical chemistry
ISSN: 1873-4200
Titre abrégé: Biophys Chem
Pays: Netherlands
ID NLM: 0403171

Informations de publication

Date de publication:
08 2022
Historique:
received: 20 03 2022
revised: 21 05 2022
accepted: 22 05 2022
pubmed: 7 6 2022
medline: 18 6 2022
entrez: 6 6 2022
Statut: ppublish

Résumé

The affinity between amino acid and water is important for understanding how proteins behave in aqueous solutions. For example, the hydrophobicity of amino acid side chains determines a protein's solubility. However, the affinity of amino acid side chains in amino acid solvents should be determined in order to understand the propensity of protein condensates induced by multivalent amino acid interactions. Here we measured the transfer free energy of amino acid side chains (ΔG

Identifiants

pubmed: 35667130
pii: S0301-4622(22)00073-4
doi: 10.1016/j.bpc.2022.106831
pii:
doi:

Substances chimiques

Amino Acids 0
Amino Acids, Aromatic 0
Proteins 0
Solvents 0
Water 059QF0KO0R

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

106831

Informations de copyright

Copyright © 2022 Elsevier B.V. All rights reserved.

Auteurs

Akira Nomoto (A)

Faculty of Pure and Applied Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8573, Japan.

Suguru Nishinami (S)

Faculty of Pure and Applied Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8573, Japan.

Kentaro Shiraki (K)

Faculty of Pure and Applied Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8573, Japan. Electronic address: shiraki.kentaro.gb@u.tsukuba.ac.jp.

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Classifications MeSH