Histone editing elucidates the functional roles of H3K27 methylation and acetylation in mammals.

Acetylation Animals Chromatin / genetics Drosophila melanogaster / genetics Histones / genetics Mammals / genetics Methylation Mice Polycomb Repressive Complex 2 / genetics Protein Processing, Post-Translational / genetics

Journal

Nature genetics
ISSN: 1546-1718
Titre abrégé: Nat Genet
Pays: United States
ID NLM: 9216904

Informations de publication

Date de publication:
06 2022
Historique:
received: 16 02 2021
accepted: 04 05 2022
pubmed: 7 6 2022
medline: 18 6 2022
entrez: 6 6 2022
Statut: ppublish

Résumé

Posttranslational modifications of histones (PTMs) are associated with specific chromatin and gene expression states

Identifiants

DOI: 10.1038/s41588-022-01091-2 PMID: 35668298
pubmed: 35668298
doi: 10.1038/s41588-022-01091-2
pii: 10.1038/s41588-022-01091-2
doi:

Substances chimiques

Chromatin 0
Histones 0
Polycomb Repressive Complex 2 EC 2.1.1.43

Types de publication

Journal Article Research Support, Non-U.S. Gov't Research Support, N.I.H., Extramural

Langues

eng

Sous-ensembles de citation

IM

Pagination

754-760

Subventions

Organisme : NCI NIH HHS
ID : P30 CA008748
Pays : United States

Commentaires et corrections

Type : CommentIn

Informations de copyright

© 2022. The Author(s), under exclusive licence to Springer Nature America, Inc.

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Auteurs

Aditya Sankar (A)

Biotech Research Innovation Centre (BRIC), Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
The Novo Nordisk Foundation Center for Stem Cell Biology (DanStem), University of Copenhagen, Copenhagen, Denmark.
ORCID: 0000-0002-1840-3356

Faizaan Mohammad (F)

Biotech Research Innovation Centre (BRIC), Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
The Novo Nordisk Foundation Center for Stem Cell Biology (DanStem), University of Copenhagen, Copenhagen, Denmark.

Arun Kumar Sundaramurthy (AK)

Biotech Research Innovation Centre (BRIC), Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
The Novo Nordisk Foundation Center for Stem Cell Biology (DanStem), University of Copenhagen, Copenhagen, Denmark.
ORCID: 0000-0003-1287-0591

Hua Wang (H)

Cell Biology Program and Center for Epigenetics Research, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

Mads Lerdrup (M)

Center for Chromosome Stability (CCS), Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.

Tulin Tatar (T)

Biotech Research Innovation Centre (BRIC), Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
The Novo Nordisk Foundation Center for Stem Cell Biology (DanStem), University of Copenhagen, Copenhagen, Denmark.
The Institute of Cancer Research (ICR), London, UK.
ORCID: 0000-0003-3289-3299

Kristian Helin (K)

Biotech Research Innovation Centre (BRIC), Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. kristian.helin@icr.ac.uk.
The Novo Nordisk Foundation Center for Stem Cell Biology (DanStem), University of Copenhagen, Copenhagen, Denmark. kristian.helin@icr.ac.uk.
Cell Biology Program and Center for Epigenetics Research, Memorial Sloan Kettering Cancer Center, New York, NY, USA. kristian.helin@icr.ac.uk.
The Institute of Cancer Research (ICR), London, UK. kristian.helin@icr.ac.uk.
ORCID: 0000-0003-1975-6097

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Classifications MeSH

questionsmedicales.fr › Métabolisme › Acylation › Acétylation › Histone editing elucidates the functional...
questionsmedicales.fr › Eucaryotes › Animaux › Histone editing elucidates the functional...
questionsmedicales.fr › Phénomènes génétiques › Structures génétiques › Structures de chromosome › Chromatine › Histone editing elucidates the functional...
questionsmedicales.fr › Eucaryotes › Animaux › Invertébrés › Arthropodes › Insectes › Pterygota › Neoptera › Holometabola › Diptera › Drosophilidae › Drosophila › Drosophila melanogaster › Histone editing elucidates the functional...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Nucléoprotéines › Histone › Histone editing elucidates the functional...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Histone editing elucidates the functional...
questionsmedicales.fr › Métabolisme › Alkylation › Méthylation › Histone editing elucidates the functional...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Histone editing elucidates the functional...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Facteurs de transcription › Protéines de répression › Protéines du groupe Polycomb › Complexe répresseur Polycomb-2 › Histone editing elucidates the functional...
questionsmedicales.fr › Phénomènes génétiques › Régulation de l'expression des gènes › Modification traductionnelle des protéines › Maturation post-traductionnelle des protéines › Histone editing elucidates the functional...