Metabolomics prospect of obesity and metabolic syndrome; a systematic review.
Metabolic syndrome
Metabolite
Metabolomics
Obesity
Journal
Journal of diabetes and metabolic disorders
ISSN: 2251-6581
Titre abrégé: J Diabetes Metab Disord
Pays: Switzerland
ID NLM: 101590741
Informations de publication
Date de publication:
Jun 2022
Jun 2022
Historique:
received:
29
07
2021
accepted:
06
10
2021
entrez:
8
6
2022
pubmed:
9
6
2022
medline:
9
6
2022
Statut:
epublish
Résumé
Due to growing concerns about the obesity pandemic as a worldwide phenomenon, a global effort has been made for managing it and associated disorders. Accordingly, metabolomics as a promising field of "OMICS" is presented for investigating different molecular pathways in obesity and related disorders through the evaluation of specific metabolites in both animal and human subjects. Herein, the aim of the present study as the first systematic review is to evaluate all available studies about different mechanisms and their biomarkers discovery using metabolomics approaches. The study was designed according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Using a comprehensive search strategy we searched in databases including; Web of Science, PubMed, and Scopus using specific keywords. Based on predefined inclusion/exclusion criteria study selection has been conducted considering the type of studies, participant, and outcome measures. Quality assessment was done using CASP (Critical Appraisal Skills Programme) checklist followed by data extraction according to a predefined data extraction sheet. Among the articles that resulted from electronic search, a total of 74 articles met our inclusion criteria. The most prevalent studied metabolites were amino acids and lipid derivatives and both targeted and non-targeted approaches were applied for metabolomics studies. This systematic review summarized a wide range of studies regardless of the age, history, language, and type of the study. Further studies are needed to compare the application of emerging methods in the treatment of obesity and related disorders. The online version contains supplementary material available at 10.1007/s40200-021-00917-w.
Identifiants
pubmed: 35673462
doi: 10.1007/s40200-021-00917-w
pii: 917
pmc: PMC9167361
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
889-917Informations de copyright
© Springer Nature Switzerland AG 2021.
Déclaration de conflit d'intérêts
Conflict of interestThe authors have nothing to disclose.
Références
J Pediatr (Rio J). 2015 Mar-Apr;91(2):196-205
pubmed: 25449791
Obes Facts. 2017;10(2):85-100
pubmed: 28376503
Placenta. 2018 Jan;61:89-95
pubmed: 29277276
PLoS Med. 2014 Dec 09;11(12):e1001765
pubmed: 25490400
FASEB J. 2017 Dec;31(12):5557-5567
pubmed: 28821636
J Dev Orig Health Dis. 2012 Dec;3(6):409-14
pubmed: 25084293
Oncotarget. 2017 Oct 4;8(51):88882-88893
pubmed: 29179484
Metabolomics. 2015;11:9-26
pubmed: 25598764
J Biosci Bioeng. 2013 Jul;116(1):9-16
pubmed: 23466298
Clin Chim Acta. 2016 Dec 1;463:53-61
pubmed: 27720726
FASEB J. 2017 Sep;31(9):3904-3912
pubmed: 28490483
J Proteome Res. 2014 Sep 5;13(9):4062-73
pubmed: 25132568
Biochim Biophys Acta. 2012 Jun;1821(6):908-13
pubmed: 22370449
Obesity (Silver Spring). 2010 Sep;18(9):1695-700
pubmed: 20111019
Br J Nutr. 2016 Dec;116(11):1954-1965
pubmed: 27976603
Obesity (Silver Spring). 2016 Jun;24(6):1380-8
pubmed: 27129722
Lipids Health Dis. 2018 May 9;17(1):103
pubmed: 29743087
Anal Chim Acta. 2014 May 27;827:22-7
pubmed: 24832990
Bioanalysis. 2017 Nov;9(21):1623-1626
pubmed: 29095044
Mol Nutr Food Res. 2019 Jan;63(1):e1700889
pubmed: 29714050
Nutrients. 2013 Apr 12;5(4):1218-40
pubmed: 23584084
Nutrients. 2019 Jan 26;11(2):
pubmed: 30691143
Anal Biochem. 2006 May 15;352(2):274-81
pubmed: 16600169
J Proteome Res. 2017 Feb 3;16(2):635-644
pubmed: 27966366
PLoS One. 2013 Oct 02;8(10):e74927
pubmed: 24098359
J Clin Endocrinol Metab. 2016 Nov;101(11):4329-4337
pubmed: 27504851
Steroids. 2014 Oct;88:83-9
pubmed: 25042470
Metabolomics. 2016 Mar;12(3):
pubmed: 27346989
Obes Rev. 2013 Oct;14(10):839-57
pubmed: 23800284
J Chromatogr B Analyt Technol Biomed Life Sci. 2011 Oct 1;879(27):2871-6
pubmed: 21890434
Nutr Metab Cardiovasc Dis. 2018 Feb;28(2):112-118
pubmed: 29122443
Diabetes Care. 2012 Mar;35(3):605-11
pubmed: 22266733
Obesity (Silver Spring). 2017 Feb;25(2):323-331
pubmed: 28000430
Acta Diabetol. 2019 Apr;56(4):421-430
pubmed: 30725264
Int J Mol Sci. 2020 Jan 15;21(2):
pubmed: 31952343
Diabetologia. 2017 Mar;60(3):518-530
pubmed: 27981358
N Engl J Med. 2017 Jul 6;377(1):13-27
pubmed: 28604169
Exp Biol Med (Maywood). 2017 Apr;242(7):773-780
pubmed: 28299975
Iran J Basic Med Sci. 2020 Feb;23(2):186-194
pubmed: 32405361
Genome Med. 2016 Jun 10;8(1):64
pubmed: 27286979
PLoS One. 2016 Jun 01;11(6):e0156612
pubmed: 27249024
J Steroid Biochem Mol Biol. 2016 Sep;162:100-9
pubmed: 27154415
Mol Cells. 2015 Jul;38(7):587-96
pubmed: 26072981
Adv Exp Med Biol. 2010;688:1-23
pubmed: 20919643
Am J Physiol Heart Circ Physiol. 2007 Feb;292(2):H904-11
pubmed: 17012356
Diabetes Res Clin Pract. 2017 Oct;132:45-58
pubmed: 28783532
Diabetes Metab Res Rev. 2018 Nov;34(8):e3045
pubmed: 30003682
PLoS One. 2016 Feb 10;11(2):e0148361
pubmed: 26863521
Nature. 2017 Jan 5;541(7635):81-86
pubmed: 28002404
Diabetes Care. 2013 Jun;36(6):1729-31
pubmed: 23275373
Int J Mol Sci. 2016 Dec 09;17(12):
pubmed: 27941699
Lipids Health Dis. 2019 Apr 9;18(1):94
pubmed: 30967146
Int J Obes (Lond). 2015 Aug;39(8):1241-8
pubmed: 25907313
Biomed Chromatogr. 2016 Jan;30(1):48-54
pubmed: 26043712
PLoS One. 2017 Apr 12;12(4):e0175133
pubmed: 28403191
Int J Obes (Lond). 2013 Aug;37(8):1064-70
pubmed: 23207405
PLoS Comput Biol. 2019 Jan 14;15(1):e1006734
pubmed: 30640898
J Clin Endocrinol Metab. 2014 Dec;99(12):4730-9
pubmed: 25202817
Cell Metab. 2008 Jan;7(1):45-56
pubmed: 18177724
Am J Clin Nutr. 2015 Aug;102(2):256-67
pubmed: 26085512
J Inherit Metab Dis. 2010 Oct;33(5):469-77
pubmed: 20195903
Int J Obes (Lond). 2017 Jan;41(1):159-169
pubmed: 27569686
J Proteome Res. 2014 Jul 3;13(7):3455-66
pubmed: 24933025
J Gerontol A Biol Sci Med Sci. 2017 Oct 1;72(10):1352-1359
pubmed: 28052980
FASEB J. 2015 Mar;29(3):748-58
pubmed: 25411437
Asia Pac J Clin Nutr. 2018;27(5):1067-1076
pubmed: 30272855
J Diabetes. 2019 Feb;11(2):148-160
pubmed: 30058212
Int J Health Policy Manag. 2014 Apr 03;2(3):109-14
pubmed: 24757686
J Med Food. 2019 May;22(5):499-507
pubmed: 30990731
Pediatr Obes. 2017 Apr;12(2):93-101
pubmed: 26910390
Environ Int. 2018 Dec;121(Pt 1):159-168
pubmed: 30208345
PLoS One. 2018 May 31;13(5):e0198156
pubmed: 29851973
Int J Obes (Lond). 2018 Jan;42(1):72-78
pubmed: 28947825
Sci Transl Med. 2015 Apr 29;7(285):285ra62
pubmed: 25925681
J Proteome Res. 2018 Aug 3;17(8):2704-2714
pubmed: 29893570
PLoS One. 2012;7(6):e40009
pubmed: 22761945
Mayo Clin Proc. 2013 Oct;88(10):1127-40
pubmed: 24079682
Pediatr Obes. 2013 Feb;8(1):52-61
pubmed: 22961720
Nestle Nutr Inst Workshop Ser. 2013;71:11-27
pubmed: 23502135
Nutrients. 2016 May 27;8(6):
pubmed: 27240400
Curr Opin Endocrinol Diabetes Obes. 2009 Apr;16(2):163-71
pubmed: 19306528
Menopause. 2016 Jul;23(7):749-58
pubmed: 27070805
Mol Biosyst. 2015 Jul;11(7):1742-74
pubmed: 25919044
Am J Clin Nutr. 2005 Sep;82(3):497-503
pubmed: 16155259
PLoS One. 2016 Jul 19;11(7):e0159548
pubmed: 27434237
Obesity (Silver Spring). 2014 Dec;22(12):2570-8
pubmed: 25251340
Cell Metab. 2005 Oct;2(4):251-61
pubmed: 16213227
PLoS One. 2007 Feb 14;2(2):e218
pubmed: 17299598
Metabolites. 2019 Apr 04;9(4):
pubmed: 30987392
J Proteome Res. 2010 Sep 3;9(9):4368-75
pubmed: 20560578
J Clin Endocrinol Metab. 2016 Mar;101(3):871-9
pubmed: 26709969
J Clin Endocrinol Metab. 2016 Apr;101(4):1779-89
pubmed: 26908103
J Diabetes Metab Disord. 2014 Jan 29;13(1):21
pubmed: 24476086
Int J Obes (Lond). 2018 Oct;42(10):1782-1796
pubmed: 29892041
Biochim Biophys Acta. 2000 Dec 15;1529(1-3):245-56
pubmed: 11111093
Lancet. 2017 Dec 16;390(10113):2627-2642
pubmed: 29029897
J Proteome Res. 2018 Aug 3;17(8):2600-2610
pubmed: 29877711
J R Soc Interface. 2014 Feb 26;11(94):20130908
pubmed: 24573330
Int J Epidemiol. 2010 Dec;39(6):1647-55
pubmed: 20797988
Obes Facts. 2012;5(5):660-70
pubmed: 23108202
Obesity (Silver Spring). 2017 Sep;25(9):1549-1555
pubmed: 28758369
Sci Rep. 2018 Feb 19;8(1):3308
pubmed: 29459697