Carboplatin Niosomal Nanoplatform for Potentiated Chemotherapy.

Animals Carboplatin Cell Line, Tumor Drug Carriers Liposomes Mice Nanoparticles Neoplasms / drug therapy Polyethylene Glycols
Breast cancer Carboplatin Drug delivery Nanoparticle Niosome

Journal

Journal of pharmaceutical sciences
ISSN: 1520-6017
Titre abrégé: J Pharm Sci
Pays: United States
ID NLM: 2985195R

Informations de publication

Date de publication:
11 2022
Historique:
received: 16 03 2022
revised: 02 06 2022
accepted: 02 06 2022
pubmed: 9 6 2022
medline: 19 10 2022
entrez: 8 6 2022
Statut: ppublish

Résumé

This study aimed to characterize a stable nano-niosome formulation, which could reduce the adverse effects of carboplatin (CB) and improve its therapeutic efficacy in the treatment of breast cancer. For this purpose, CB-loaded polyethylene glycol (PEG)ylated niosome nanoparticles (PEG-NS-CB) were synthesized using the reverse-phase evaporation method. PEG-NS-CB (226.0 ± 10.6 nm) could release CB in a controlled manner and, compared to CB and CB-loaded non-PEGylated niosome (NS-CB), caused higher cytotoxicity effects against mouse breast cancer 4T1 cells (IC

Identifiants

DOI: 10.1016/j.xphs.2022.06.002 PMID: 35675875
pubmed: 35675875
pii: S0022-3549(22)00246-5
doi: 10.1016/j.xphs.2022.06.002
pii:
doi:

Substances chimiques

Drug Carriers 0
Liposomes 0
Polyethylene Glycols 3WJQ0SDW1A
Carboplatin BG3F62OND5

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

3029-3037

Informations de copyright

Copyright © 2022 American Pharmacists Association. Published by Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of Competing Interest The authors declare no conflict of interest.

Auteurs

Seyed Ebrahim Alavi (SE)

Immunology of Infectious Diseases Research Center, Research Institute of Basic Medical Sciences, Rafsanjan University of Medical Sciences, Rafsanjan, Iran; Department of Microbiology, School of Medicine, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.

Aun Raza (A)

School of Pharmacy, The University of Queensland, Woolloongabba 4102, Australia.

Maedeh Koohi Moftakhari Esfahani (M)

Immunology of Infectious Diseases Research Center, Research Institute of Basic Medical Sciences, Rafsanjan University of Medical Sciences, Rafsanjan, Iran; Department of Microbiology, School of Medicine, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.

Azim Akbarzadeh (A)

Department of Pilot Nanobiotechnology, Pasteur Institute of Iran, Tehran, Iran.

Seyed Hossein Abdollahi (SH)

Department of Microbiology, School of Medicine, Rafsanjan University of Medical Sciences, Rafsanjan, Iran; Molecular Medicine Research Center, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.

Hasan Ebrahimi Shahmabadi (H)

Immunology of Infectious Diseases Research Center, Research Institute of Basic Medical Sciences, Rafsanjan University of Medical Sciences, Rafsanjan, Iran; Department of Microbiology, School of Medicine, Rafsanjan University of Medical Sciences, Rafsanjan, Iran. Electronic address: ebrahimi@rums.ac.ir.

Articles similaires

Evaluating the efficacy of telesurgery with dual console SSI Mantra Surgical Robotic System: experiment on animal model and clinical trials.

Sudhir Prem Srivastava, Vishwajyoti Pascual Srivastava, Avinesh Singh et al.
1.00
Robotic Surgical Procedures Animals Humans Telemedicine Models, Animal

Odour generalisation and detection dog training.

Lyn Caldicott, Thomas W Pike, Helen E Zulch et al.
1.00
Animals Odorants Dogs Generalization, Psychological Smell

FBXO22 inhibits colitis and colorectal carcinogenesis by regulating the degradation of the S2448-phosphorylated form of mTOR.

Minle Li, Xuan Chen, Pengfei Qu et al.
1.00
Animals TOR Serine-Threonine Kinases Colorectal Neoplasms Colitis Mice

Use of organic material provided by an automatic enrichment device by weaner pigs and its influence on tail lesions.

Philipp Heseker, Jeanette Probst, Stefanie Ammer et al.
1.00
Animals Tail Swine Behavior, Animal Animal Husbandry

Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Carboplatin Niosomal Nanoplatform for...
questionsmedicales.fr › Composés chimiques organiques › Complexes de coordination › Carboplatine › Carboplatin Niosomal Nanoplatform for...
questionsmedicales.fr › Cellules › Cellules cultivées › Cellules cancéreuses en culture › Lignée cellulaire tumorale › Carboplatin Niosomal Nanoplatform for...
questionsmedicales.fr › Thérapeutique › Traitement médicamenteux › Systèmes de délivrance de médicaments › Vecteurs de médicaments › Carboplatin Niosomal Nanoplatform for...
questionsmedicales.fr › Technologie, industrie et agriculture › Produits manufacturés › Matériaux biomimétiques › Membrane artificielle › Liposomes › Carboplatin Niosomal Nanoplatform for...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Carboplatin Niosomal Nanoplatform for...
questionsmedicales.fr › Technologie, industrie et agriculture › Produits manufacturés › Nanostructures › Nanoparticules › Carboplatin Niosomal Nanoplatform for...
questionsmedicales.fr › Tumeurs › Carboplatin Niosomal Nanoplatform for...
questionsmedicales.fr › Technologie, industrie et agriculture › Produits manufacturés › Matériaux biomédicaux et dentaires › Polymères › Polyéthylène glycols › Carboplatin Niosomal Nanoplatform for...