Cohesin-mediated loop anchors confine the locations of human replication origins.

Cell Cycle Proteins / metabolism Chromatin / genetics Chromosomal Proteins, Non-Histone / metabolism DNA Replication Humans Replication Origin / genetics S Phase Cohesins

Journal

Nature
ISSN: 1476-4687
Titre abrégé: Nature
Pays: England
ID NLM: 0410462

Informations de publication

Date de publication:
06 2022
Historique:
received: 31 12 2020
accepted: 26 04 2022
pubmed: 9 6 2022
medline: 25 6 2022
entrez: 8 6 2022
Statut: ppublish

Résumé

DNA replication occurs through an intricately regulated series of molecular events and is fundamental for genome stability

Identifiants

DOI: 10.1038/s41586-022-04803-0 PMID: 35676475 PMC: PMC9217744
pubmed: 35676475
doi: 10.1038/s41586-022-04803-0
pii: 10.1038/s41586-022-04803-0
pmc: PMC9217744
doi:

Substances chimiques

Cell Cycle Proteins 0
Chromatin 0
Chromosomal Proteins, Non-Histone 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

812-819

Subventions

Organisme : NIMH NIH HHS
ID : R01 MH120269
Pays : United States
Organisme : NHGRI NIH HHS
ID : UM1 HG011536
Pays : United States
Organisme : NHGRI NIH HHS
ID : R01 HG010658
Pays : United States
Organisme : NIMH NIH HHS
ID : DP1 MH129957
Pays : United States
Organisme : NIDA NIH HHS
ID : U01 DA052715
Pays : United States
Organisme : NIDDK NIH HHS
ID : U54 DK107965
Pays : United States
Organisme : NIDDK NIH HHS
ID : U01 DK127405
Pays : United States
Organisme : NHLBI NIH HHS
ID : U01 HL129998
Pays : United States
Organisme : Howard Hughes Medical Institute
Pays : United States
Organisme : NIDDK NIH HHS
ID : U54 DK107980
Pays : United States

Informations de copyright

© 2022. The Author(s).

Références

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Auteurs

Daniel J Emerson (DJ)

Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, USA.
Epigenetics Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

Peiyao A Zhao (PA)

Department of Biological Science, Florida State University, Tallahassee, FL, USA.

Ashley L Cook (AL)

Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, USA.
Epigenetics Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
ORCID: 0000-0001-6789-5732

R Jordan Barnett (RJ)

Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, USA.
Epigenetics Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

Kyle N Klein (KN)

Department of Biological Science, Florida State University, Tallahassee, FL, USA.

Dalila Saulebekova (D)

Institut Curie, PSL Research University, CNRS UMR3244, Dynamics of Genetic Information, Sorbonne Université, Paris, France.

Chunmin Ge (C)

Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, USA.
Epigenetics Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

Linda Zhou (L)

Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, USA.
Epigenetics Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

Zoltan Simandi (Z)

Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, USA.
Epigenetics Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

Miriam K Minsk (MK)

Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, USA.
Epigenetics Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

Katelyn R Titus (KR)

Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, USA.
Epigenetics Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

Weitao Wang (W)

Institut Curie, PSL Research University, CNRS UMR3244, Dynamics of Genetic Information, Sorbonne Université, Paris, France.

Wanfeng Gong (W)

Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, USA.
Epigenetics Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

Di Zhang (D)

Children's Hospital of Pennsylvania, Philadelphia, PA, USA.
ORCID: 0000-0002-9007-4665

Liyan Yang (L)

University of Massachusetts Chan Medical School, Worcester, MA, USA.

Sergey V Venev (SV)

University of Massachusetts Chan Medical School, Worcester, MA, USA.
ORCID: 0000-0002-1507-7460

Johan H Gibcus (JH)

University of Massachusetts Chan Medical School, Worcester, MA, USA.
ORCID: 0000-0002-0851-7560

Hongbo Yang (H)

Department of Biochemistry and Molecular Genetics, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.

Takayo Sasaki (T)

San Diego Biomedical Research Institute, San Diego, CA, USA.
ORCID: 0000-0001-7609-9316

Masato T Kanemaki (MT)

Department of Chromosome Science, National Institute of Genetics, Research Organization of Information and Systems (ROIS), Mishima, Japan.
Department of Genetics, The Graduate University for Advanced Studies (Sokendai), Mishima, Japan.
ORCID: 0000-0002-7657-1649

Feng Yue (F)

Department of Biochemistry and Molecular Genetics, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
ORCID: 0000-0002-7954-5462

Job Dekker (J)

University of Massachusetts Chan Medical School, Worcester, MA, USA.
Howard Hughes Medical Institute, Chevy Chase, MD, USA.
ORCID: 0000-0001-5631-0698

Chun-Long Chen (CL)

Institut Curie, PSL Research University, CNRS UMR3244, Dynamics of Genetic Information, Sorbonne Université, Paris, France.
ORCID: 0000-0002-4795-0295

David M Gilbert (DM)

Department of Biological Science, Florida State University, Tallahassee, FL, USA.
San Diego Biomedical Research Institute, San Diego, CA, USA.
ORCID: 0000-0001-8087-9737

Jennifer E Phillips-Cremins (JE)

Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, USA. jcremins@seas.upenn.edu.
Epigenetics Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. jcremins@seas.upenn.edu.
Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. jcremins@seas.upenn.edu.
New York Stem Cell Foundation Robertson Investigator, New York, NY, USA. jcremins@seas.upenn.edu.
ORCID: 0000-0002-4702-0450

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Classifications MeSH

questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines du cycle cellulaire › Cohesin-mediated loop anchors confine the...
questionsmedicales.fr › Phénomènes génétiques › Structures génétiques › Structures de chromosome › Chromatine › Cohesin-mediated loop anchors confine the...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Nucléoprotéines › Protéines chromosomiques nonhistones › Cohesin-mediated loop anchors confine the...
questionsmedicales.fr › Phénomènes génétiques › Réplication de l'ADN › Cohesin-mediated loop anchors confine the...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Cohesin-mediated loop anchors confine the...
questionsmedicales.fr › Phénomènes génétiques › Structures génétiques › Génome › Composants de génome › Réplicon › Origine de réplication › Cohesin-mediated loop anchors confine the...
questionsmedicales.fr › Phénomènes génétiques › Réplication de l'ADN › Phase S › Cohesin-mediated loop anchors confine the...