Progress of Dicyanomethylene-4H-Pyran Derivatives in Biological Sensing Based on ICT Effect.
bioimaging
biosensor
dicyanomethylene-4H-pyran (DCM)
intramolecular charge transfer
near-infrared probe
Journal
Frontiers in chemistry
ISSN: 2296-2646
Titre abrégé: Front Chem
Pays: Switzerland
ID NLM: 101627988
Informations de publication
Date de publication:
2022
2022
Historique:
received:
24
03
2022
accepted:
20
04
2022
entrez:
9
6
2022
pubmed:
10
6
2022
medline:
10
6
2022
Statut:
epublish
Résumé
As one of the typical fluorescent cores, dicyanomethylene-4H-pyran (DCM) derivatives exhibit excellent photophysical and photochemical properties, such as large Stokes shift, excellent light stability, and tunable near-infrared (NIR) emission. The luminescence mechanism of DCM probes mainly depends on the intramolecular charge transfer (ICT). Hence, by regulating the ICT process, the probes can specifically act on the target molecule. Accordingly, a series of NIR DCM probes have been constructed to detect the ions, reactive oxygen species (ROS), and biological macromolecules in cells. However, there is no relevant review to summarize it at present. This minireview mainly summarizes the NIR DCM probes based on ICT effect and their applications in biosensors and biological imaging in recent years. This will be beneficial to innovatively construct new DCM probes and actively promote their application in the future.
Identifiants
pubmed: 35677595
doi: 10.3389/fchem.2022.903253
pii: 903253
pmc: PMC9167996
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
903253Informations de copyright
Copyright © 2022 Hou, Cai, Zhang, Wang, Tang, Zhu and Wang.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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