Dialysis modality utilization patterns and mortality in older persons initiating dialysis in Australia and New Zealand.


Journal

Nephrology (Carlton, Vic.)
ISSN: 1440-1797
Titre abrégé: Nephrology (Carlton)
Pays: Australia
ID NLM: 9615568

Informations de publication

Date de publication:
Aug 2022
Historique:
revised: 27 04 2022
received: 12 02 2022
accepted: 28 05 2022
pubmed: 10 6 2022
medline: 15 7 2022
entrez: 9 6 2022
Statut: ppublish

Résumé

The benefits of dialysis in the older population remain highly debated, particularly for certain dialysis modalities. This study aimed to explore the dialysis modality utilization patterns between in-centre haemodialysis (ICHD), peritoneal dialysis (PD) and home haemodialysis (HHD) and their association with outcomes in older persons. Older persons (≥75 years) initiating dialysis in Australia and New Zealand from 1999 to 2018 reported to the Australia and New Zealand Dialysis and Transplant (ANZDATA) registry were included. The main aim of the study was to characterize dialysis modality utilization patterns and describe individual characteristics of each pattern. Relationships between identified patterns and survival, causes of death and withdrawal were examined as secondary analyses, where the pattern was considered as the exposure. A total of 10 306 older persons initiated dialysis over the study period. Of these, 6776 (66%) and 1535 (15%) were exclusively treated by ICHD and PD, respectively, while 136 (1%) ever received HHD during their dialysis treatment course. The remainder received both ICHD and PD: 906 (9%) started dialysis on ICHD and 953 (9%) on PD. Different individual characteristics were seen across dialysis modality utilization patterns. Median survival time was 3.0 (95%CI 2.9-3.1) years. Differences in survival were seen across groups and varied depending on the time period following dialysis initiation. Dialysis withdrawal was an important cause of death and varied according to individual characteristics and utilization patterns. This study showed that dialysis modality utilization patterns in older persons are associated with mortality, independent of individual characteristics.

Identifiants

pubmed: 35678544
doi: 10.1111/nep.14073
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

663-672

Subventions

Organisme : Centre Hospitalier de l'Université de Montréal and the Fondation du CHUM
Organisme : National Health and Medical Research Council
ID : 1196033
Organisme : Queensland Advancing Clinical Research Fellowship

Informations de copyright

© 2022 Asian Pacific Society of Nephrology.

Références

Jassal SV, Watson D. Dialysis in late life: benefit or burden. Clin J Am Soc Nephrol. 2009;4(12):2008-2012. doi:10.2215/CJN.04610709
Fung E, Kurella TM. Epidemiology and public health concerns of CKD in older adults. Adv Chronic Kidney Dis. 2016;23(1):8-11. doi:10.1053/j.ackd.2015.10.001
Lassalle M, Monnet E, Ayav C, Hogan J, Moranne O, Couchoud C. 2017 annual report digest of the renal epidemiology information network (REIN) registry. Transpl Int. 2019;32(9):892-902. doi:10.1111/tri.13466
ANZDATA Registry. 42nd Report, Chapter 4: haemodialysis. http://www.anzdata.org.au. 2019. Accessed September 8, 2020.
ANZDATA Registry. 42nd Report, Chapter 5: peritoneal dialysis. Australia and New Zealand Dialysis and Transplant Registry. http://www.anzdata.org.au. 2019. Accessed September 8, 2020.
Auguste BL, Chan CT. Home dialysis among elderly patients: outcomes and future directions. Can J Kidney Health Dis. 2019;6:1-6. doi:10.1177/2054358119871031
Corbett RW, Brown EA. Conventional dialysis in the elderly: how lenient should our guidelines be? Semin Dial. 2018;31(6):607-611. doi:10.1111/sdi.12744
Berger JR, Jaikaransingh V, Hedayati SS. End-stage kidney disease in the elderly: approach to dialysis initiation, choosing modality, and predicting outcomes. Adv Chronic Kidney Dis. 2016;23(1):36-43. doi:10.1053/j.ackd.2015.08.005
Brown EA, Finkelstein FO, Iyasere OU, Kliger AS. Peritoneal or hemodialysis for the frail elderly patient, the choice of 2 evils? Kidney Int. 2017;91(2):294-303. doi:10.1016/j.kint.2016.08.026
Misra PS, Bargman JM, Perl J. Survival comparisons in home dialysis: where you finish depends on where you start. Am J Kidney Dis. 2016;67(1):13-15. doi:10.1053/j.ajkd.2015.10.001
von Elm E, Altman DG, Egger M, Pocock SJ, Gotzsche PC, Vandenbroucke JP. The strengthening the reporting of observational studies in epidemiology (STROBE) Statement: guidelines for reporting. Ann Intern Med. 2007;147(8):573-577.
Australian Bureau of Statistics. Census of population and housing: socio-Economic Indexes for Areas (SEIFA), Australia, 2016. https://www.abs.gov.au/ausstats/abs@.nsf/Lookup/bySubject/2033.0.55.001~2016~MainFeatures~SEIFABasics~5. Accessed October 12, 2020.
Alfaadhel TA, Soroka SD, Kiberd BA, Landry D, Moorhouse P, Tennankore KK. Frailty and mortality in dialysis: evaluation of a clinical frailty scale. Clin J Am Soc Nephrol. 2015;10(5):832-840. doi:10.2215/CJN.07760814
Bao Y, Dalrymple L, Chertow GM, Kaysen GA, Johansen KL. Frailty, dialysis initiation, and mortality in end-stage renal disease. Arch Intern Med. 2012;172(14):1071-1077. doi:10.1001/archinternmed.2012.3020
Garcia-Canton C, Rodenas A, Lopez-Aperador C, et al. Frailty in hemodialysis and prediction of poor short-term outcome: mortality, hospitalization and visits to hospital emergency services. Ren Fail. 2019;41(1):567-575. doi:10.1080/0886022X.2019.1628061
Johansen KL, Chertow GM, Jin C, Kutner NG. Significance of frailty among dialysis patients. J Am Soc Nephrol. 2007;18(11):2960-2967. doi:10.1681/ASN.2007020221
McAdams-Demarco MA, Suresh S, Law A, et al. Frailty and falls among adult patients undergoing chronic hemodialysis: a prospective cohort study. BMC Nephrol. 2013;14(1):1-5. doi:10.1186/1471-2369-14-224
Cornelis T, Tennankore KK, Goffin E, et al. An international feasibility study of home haemodialysis in older patients. Nephrol Dial Transplant. 2014;29(12):2327-2333. doi:10.1093/ndt/gfu260
Thomas P, Price A, Baharani J. Haemodialysis in the octogenarian: more than a decade of experience from a single UKCentre. J Geriatr. 2016;2016:1-8. doi:10.1155/2016/2310596
Iyasere O, Brown EA. Mortality in the elderly on dialysis: is this the right debate? Clin J Am Soc Nephrol. 2015;10(6):920-922. doi:10.2215/CJN.03650415
Morton RL, Snelling P, Webster AC, et al. Factors influencing patient choice of dialysis versus conservative care to treat end-stage kidney disease. CMAJ. 2012;184(5):277-283. doi:10.1503/cmaj.111355
Vandecasteele SJ, Tamura MK. A patient-centered vision of care for ESRD: dialysis as a bridging treatment or as a final destination? J Am Soc Nephrol. 2014;25(8):1647-1651. doi:10.1681/ASN.2013101082
Lobbedez T, Crand A, Le Roy F, Landru I, Quéré C, Ryckelynck JP. Transfert en dialyse péritonéale après traitement par hémodialyse chronique. Nephrol Ther. 2005;1(1):38-43. doi:10.1016/j.nephro.2005.01.001
Kim DJ, Park JA, Huh W, Kim YG, Oh H-Y. The effect of hemodialysis during break-in period on residual renal function in CAPD patients. Perit Dial Int. 2000;20:784-785.
Lobbedez T, Verger C, Ryckelynck J-P, Fabre E, Evans D. Is assisted peritoneal dialysis associated with technique survival when competing events are considered? Clin J Am Soc Nephrol. 2012;7(4):612-618. doi:10.2215/CJN.10161011
Nessim SJ, Bargman JM, Austin PC, Nisenbaum R, Jassal SV. Predictors of peritonitis in patients on peritoneal dialysis: results of a large, prospective Canadian database. Clin J Am Soc Nephrol. 2009;4(7):1195-1200. doi:10.2215/CJN.00910209
Nessim SJ, Bargman JM, Jassal SV, Oliver MJ, Na Y, Perl J. The impact of transfer from hemodialysis on peritoneal dialysis technique survival. Perit Dial Int. 2015;35(3):297-305. doi:10.3747/pdi.2013.00147
Ellwood AD, Vanita Jassal S, Suri RS, Clark WF, Na Y, Moist LM. Early dialysis initiation and rates and timing of withdrawal from dialysis in Canada. Clin J Am Soc Nephrol. 2013;8(2):265-270. doi:10.2215/CJN.01000112
Chuasuwan A, Chuasuwan A, Pooripussarakul S, et al. Comparisons of quality of life between patients underwent peritoneal dialysis and hemodialysis: a systematic review and meta-analysis. Health Qual Life Outcomes. 2020;18(1):1-11. doi:10.1186/s12955-020-01449-2
Cho Y, Badve SV, Hawley CM, et al. The effects of living distantly from peritoneal dialysis units on peritonitis risk, microbiology, treatment and outcomes: a multi-Centre registry study. BMC Nephrol. 2012;13:41.
Povlsen JV, Ivarsen P. Assisted automated peritoneal dialysis (AAPD) for the functionally dependent and elderly patient. Perit Dial Int. 2005;25(Supplement 3):S60-S63. doi:10.1097/GOX.0000000000000533
Dimkovic N, Aggarwal V, Khan S, Chu M, Bargman J, Oreopoulos DG. Assisted peritoneal dialysis: what is it and who does it involve? Adv Perit Dial. 2009;25:165-170.
Oliver MJ, Quinn RR, Richardson EP, Kiss AJ, Lamping DL, Manns BJ. Home care assistance and the utilization of peritoneal dialysis. Kidney Int. 2007;71(7):673-678. doi:10.1038/sj.ki.5002107
Gianotti Franco MR, Fernandes N, Azevedo Ribeiro C, Qureshi AR, Divino-Filho JC, da Glória LM. A Brazilian experience in assisted automated peritoneal dialysis: a reliable and effective home care approach. Perit Dial Int. 2013;33(3):252-258. doi:10.3747/pdi.2012.00031
Lobbedez T, Moldovan R, Lecame M, de Ligny BH, El Haggan W, Ryckelynck J-P. Assisted peritoneal dialysis. Experience in a French renal department. Perit Dial Int. 2006;26(6):671-676.
Bevilacqua MU, Turnbull L, Saunders S, et al. Evaluation of a 12-month pilot of long-term and temporary assisted peritoneal dialysis. Perit Dial Int. 2017;37(3):307-313. doi:10.3747/pdi.2016.00201

Auteurs

Isabelle Ethier (I)

Division of Nephrology, Centre Hospitalier de l'Université de Montréal, Montréal, Québec, Canada.
Department of Nephrology, Princess Alexandra Hospital, Brisbane, Queensland, Australia.

Scott B Campbell (SB)

Department of Nephrology, Princess Alexandra Hospital, Brisbane, Queensland, Australia.

Yeoungjee Cho (Y)

Department of Nephrology, Princess Alexandra Hospital, Brisbane, Queensland, Australia.
Australia and New Zealand Dialysis and Transplant (ANZDATA) Registry, South Australian Health and Medical Research Institute (SAHMRI), Adelaide, South Australia, Australia.
Australasian Kidney Trials Network, University of Queensland, Brisbane, Queensland, Australia.

Carmel M Hawley (CM)

Department of Nephrology, Princess Alexandra Hospital, Brisbane, Queensland, Australia.
Australia and New Zealand Dialysis and Transplant (ANZDATA) Registry, South Australian Health and Medical Research Institute (SAHMRI), Adelaide, South Australia, Australia.
Australasian Kidney Trials Network, University of Queensland, Brisbane, Queensland, Australia.
Translational Research Institute, Brisbane, Queensland, Australia.

Nicole M Isbel (NM)

Department of Nephrology, Princess Alexandra Hospital, Brisbane, Queensland, Australia.
Australasian Kidney Trials Network, University of Queensland, Brisbane, Queensland, Australia.

Rathika Krishnasamy (R)

Australasian Kidney Trials Network, University of Queensland, Brisbane, Queensland, Australia.
Department of Nephrology, Sunshine Coast University Hospital, Sunshine Coast, Queensland, Australia.

Matthew A Roberts (MA)

Eastern Health Clinical School, Monash University, Melbourne, Victoria, Australia.

David Semple (D)

Department of Renal Medicine, Auckland District Health Board, Auckland, New Zealand.
School of Medicine, University of Auckland, Auckland, New Zealand.

Matthew Sypek (M)

Australia and New Zealand Dialysis and Transplant (ANZDATA) Registry, South Australian Health and Medical Research Institute (SAHMRI), Adelaide, South Australia, Australia.

Andrea K Viecelli (AK)

Department of Nephrology, Princess Alexandra Hospital, Brisbane, Queensland, Australia.
Australasian Kidney Trials Network, University of Queensland, Brisbane, Queensland, Australia.

David W Johnson (DW)

Department of Nephrology, Princess Alexandra Hospital, Brisbane, Queensland, Australia.
Australia and New Zealand Dialysis and Transplant (ANZDATA) Registry, South Australian Health and Medical Research Institute (SAHMRI), Adelaide, South Australia, Australia.
Australasian Kidney Trials Network, University of Queensland, Brisbane, Queensland, Australia.
Translational Research Institute, Brisbane, Queensland, Australia.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH