Effect of low energy shock wave on testicular microenvironment homeostasis in rats.
Apoptosis
Low energy shock waves
Microenvironment
Proliferation
Testes
Journal
Ecotoxicology and environmental safety
ISSN: 1090-2414
Titre abrégé: Ecotoxicol Environ Saf
Pays: Netherlands
ID NLM: 7805381
Informations de publication
Date de publication:
Aug 2022
Aug 2022
Historique:
received:
25
11
2021
revised:
23
05
2022
accepted:
24
05
2022
pubmed:
10
6
2022
medline:
20
7
2022
entrez:
9
6
2022
Statut:
ppublish
Résumé
To further investigate whether two sets of low-energy extracorporeal shock waves (LESWs) impulse parameters, i.e., 0.02 mJ/mm (1) Twenty-four experimental rats were randomly divided into a 0.02 mJ/mm Compared with the other three groups, the rate of M1 testicular germ cell apoptosis induced by shock treatment was higher, the expression levels of proapoptotic proteins increased significantly while that of the antiapoptotic protein was lower, and the suppression of cell proliferation correlated with the protein expression levels. Additionally, with respect to the absolute volume of the seminiferous tubules, the absolute interstitial testicular volume notably increased, producing a series of biological effects working against testicular sperm production and function. However, there was no significant difference between the L1 group and the N and S groups. LESWs treatment with impulse parameters of 0.02 mJ/mm
Identifiants
pubmed: 35679733
pii: S0147-6513(22)00550-4
doi: 10.1016/j.ecoenv.2022.113710
pii:
doi:
Substances chimiques
Apoptosis Regulatory Proteins
0
Vascular Endothelial Growth Factor A
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
113710Commentaires et corrections
Type : ErratumIn
Informations de copyright
Copyright © 2022. Published by Elsevier Inc.