Estimation of blood lead levels in the French population using two complementary approaches: Esteban (2014-2016) as part of the human biomonitoring program and the national surveillance system for childhood lead poisoning (2015-2018).


Journal

Environmental research
ISSN: 1096-0953
Titre abrégé: Environ Res
Pays: Netherlands
ID NLM: 0147621

Informations de publication

Date de publication:
10 2022
Historique:
received: 08 02 2022
revised: 02 06 2022
accepted: 04 06 2022
pubmed: 10 6 2022
medline: 11 8 2022
entrez: 9 6 2022
Statut: ppublish

Résumé

Used widely for centuries, lead is a common environmental pollutant. As a cumulative toxic, its presence in the body is always evidence of exposure, and health effects occur without threshold. Though regulated by European directives, lead requires close monitoring due to its environmental persistence and toxicity. The first data source was the French surveillance system for monitoring childhood lead poisoning, which records the screening results of children (-18 years), providing data on their temporal and geographical distribution, characteristics, and risk factors. The second data source was Esteban, a cross-sectional study conducted in 2014-2016 on a random sample of the French population as part of the human biomonitoring program. The Esteban lead study concerns 904 children (6-17 years) and 999 adults (18-74 years), providing data on biological samples, sociodemographic characteristics, occupational exposure, environmental and dietary factors. The surveillance system highlighted that lead poisoning affected 10% of children screened between 2015 and 2018. The main risk factor remains housing. Esteban confirmed this observation, finding a general mean of blood lead level (BLL) at 9.9 and 18.5 μg/L for children and adults, respectively. In children, parents' occupation increased BLLs. In adults, the greatest exposure factors were smoking, age, place of residence, alcohol, bread-based products, and homegrown livestock products. In both, drinking tap water and year of housing construction increased BLLs. The surveillance system showed a high number of children with lead poisoning despite the implementation of prevention measures, which mainly concern lead paints in old and degraded homes. To help identify children at risk, healthcare providers need to know about exposure from housing and the emerging sources identified in the Esteban survey. Despite lower BLLs, the well-known risk factors of lead exposure persist, meaning prevention efforts must continue in order to limit their impact on the population.

Sections du résumé

BACKGROUND
Used widely for centuries, lead is a common environmental pollutant. As a cumulative toxic, its presence in the body is always evidence of exposure, and health effects occur without threshold. Though regulated by European directives, lead requires close monitoring due to its environmental persistence and toxicity.
METHODS
The first data source was the French surveillance system for monitoring childhood lead poisoning, which records the screening results of children (-18 years), providing data on their temporal and geographical distribution, characteristics, and risk factors. The second data source was Esteban, a cross-sectional study conducted in 2014-2016 on a random sample of the French population as part of the human biomonitoring program. The Esteban lead study concerns 904 children (6-17 years) and 999 adults (18-74 years), providing data on biological samples, sociodemographic characteristics, occupational exposure, environmental and dietary factors.
RESULTS
The surveillance system highlighted that lead poisoning affected 10% of children screened between 2015 and 2018. The main risk factor remains housing. Esteban confirmed this observation, finding a general mean of blood lead level (BLL) at 9.9 and 18.5 μg/L for children and adults, respectively. In children, parents' occupation increased BLLs. In adults, the greatest exposure factors were smoking, age, place of residence, alcohol, bread-based products, and homegrown livestock products. In both, drinking tap water and year of housing construction increased BLLs.
CONCLUSIONS
The surveillance system showed a high number of children with lead poisoning despite the implementation of prevention measures, which mainly concern lead paints in old and degraded homes. To help identify children at risk, healthcare providers need to know about exposure from housing and the emerging sources identified in the Esteban survey. Despite lower BLLs, the well-known risk factors of lead exposure persist, meaning prevention efforts must continue in order to limit their impact on the population.

Identifiants

pubmed: 35679905
pii: S0013-9351(22)00957-4
doi: 10.1016/j.envres.2022.113630
pii:
doi:

Substances chimiques

Environmental Pollutants 0
Lead 2P299V784P

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

113630

Informations de copyright

Copyright © 2022 Santé publique France. Published by Elsevier Inc. All rights reserved.

Auteurs

Amivi Oleko (A)

Santé Publique France, French Public Health Agency, 12 Rue du Val d'Osne, 94415, Saint Maurice Cedex, France. Electronic address: amivi.oleko@santepubliquefrance.fr.

Marie Pecheux (M)

Santé Publique France, French Public Health Agency, 12 Rue du Val d'Osne, 94415, Saint Maurice Cedex, France.

Abdesattar Saoudi (A)

Santé Publique France, French Public Health Agency, 12 Rue du Val d'Osne, 94415, Saint Maurice Cedex, France.

Abdelkrim Zeghnoun (A)

Santé Publique France, French Public Health Agency, 12 Rue du Val d'Osne, 94415, Saint Maurice Cedex, France.

Marion Hulin (M)

Santé Publique France, French Public Health Agency, 12 Rue du Val d'Osne, 94415, Saint Maurice Cedex, France.

Mélina Le Barbier (M)

Santé Publique France, French Public Health Agency, 12 Rue du Val d'Osne, 94415, Saint Maurice Cedex, France.

Céline Menard (C)

Santé Publique France, French Public Health Agency, 12 Rue du Val d'Osne, 94415, Saint Maurice Cedex, France.

Sébastien Denys (S)

Santé Publique France, French Public Health Agency, 12 Rue du Val d'Osne, 94415, Saint Maurice Cedex, France.

Clémence Fillol (C)

Santé Publique France, French Public Health Agency, 12 Rue du Val d'Osne, 94415, Saint Maurice Cedex, France.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH