Use of hypnotics among women diagnosed with cervical cancer - A population-based cohort study.
Cervical cancer
Cohort study
Epidemiology
Hypnotic use
Late effects
Sleeping problems
Journal
Gynecologic oncology
ISSN: 1095-6859
Titre abrégé: Gynecol Oncol
Pays: United States
ID NLM: 0365304
Informations de publication
Date de publication:
08 2022
08 2022
Historique:
received:
03
03
2022
revised:
18
05
2022
accepted:
23
05
2022
pubmed:
10
6
2022
medline:
29
7
2022
entrez:
9
6
2022
Statut:
ppublish
Résumé
Previous studies suggest that sleeping problems are frequent after cervical cancer. However, the evidence on the use of hypnotics is sparse. We investigated if women diagnosed with cervical cancer have an increased risk of using hypnotics and identified risk factors for prolonged use. In this nationwide register-based cohort study, 4264 women diagnosed with cervical cancer from 1997 to 2013 and 36,632 cancer-free women were followed in registers until 2016. Prolonged use of hypnotics was defined as more than three prescriptions with no more than three months in between. Data were analysed using Cox proportional hazards regression models and multistate Markov models separately for women with localized and advanced cervical cancer. The rate of first use of hypnotics was substantially increased during the first year after cervical cancer diagnosis compared to cancer-free women (HR Women diagnosed with cervical cancer are at increased risk of prolonged use of hypnotics. For the majority, treatment with hypnotics is initiated within the first year after cancer diagnosis, but the rate of first use is increased for up to five years.
Identifiants
pubmed: 35680430
pii: S0090-8258(22)00330-4
doi: 10.1016/j.ygyno.2022.05.019
pii:
doi:
Substances chimiques
Anti-Anxiety Agents
0
Antidepressive Agents
0
Hypnotics and Sedatives
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
300-307Informations de copyright
Copyright © 2022 The Authors. Published by Elsevier Inc. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of Competing Interest None declared.