In vivo detection of hydrogen sulfide in the brain of live mouse: application in neuroinflammation models.

Animals Brain / diagnostic imaging Coordination Complexes Copper Fluorescein-5-isothiocyanate Fluorescent Dyes Hydrogen Sulfide Ligands Mice Neuroinflammatory Diseases Organometallic Compounds Thiosemicarbazones Tissue Distribution
Gasotransmitter Hydrogen sulfide Imaging agent Neuroinflammation

Journal

European journal of nuclear medicine and molecular imaging
ISSN: 1619-7089
Titre abrégé: Eur J Nucl Med Mol Imaging
Pays: Germany
ID NLM: 101140988

Informations de publication

Date de publication:
Oct 2022
Historique:
received: 28 03 2022
accepted: 25 05 2022
pubmed: 11 6 2022
medline: 5 10 2022
entrez: 10 6 2022
Statut: ppublish

Résumé

Hydrogen sulfide (H Utilizing a bis(thiosemicarbazone) backbone, a fluorescent ATSM-FITC conjugate was synthesized. Its copper complex, Cu(ATSM-FITC) was thoroughly tested as a biosensor for H The Cu(ATSM-FITC) complex reacts instantly with H Our biosensor can be readily utilized to study brain H

Identifiants

DOI: 10.1007/s00259-022-05854-1 PMID: 35680737
pubmed: 35680737
doi: 10.1007/s00259-022-05854-1
pii: 10.1007/s00259-022-05854-1
doi:

Substances chimiques

Coordination Complexes 0
Fluorescent Dyes 0
Ligands 0
Organometallic Compounds 0
Thiosemicarbazones 0
Copper 789U1901C5
Fluorescein-5-isothiocyanate I223NX31W9
Hydrogen Sulfide YY9FVM7NSN

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

4073-4087

Commentaires et corrections

Type : CommentIn

Informations de copyright

© 2022. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.

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Auteurs

Bora Nam (B)

Department of Molecular Medicine, Brain Korea 21 four KNU Convergence Educational Program of Biomedical Sciences for Creative Future Talents, School of Medicine, Kyungpook National University, Daegu, 41944, South Korea.

Woonghee Lee (W)

Department of Molecular Medicine, Brain Korea 21 four KNU Convergence Educational Program of Biomedical Sciences for Creative Future Talents, School of Medicine, Kyungpook National University, Daegu, 41944, South Korea.

Swarbhanu Sarkar (S)

Department of Molecular Medicine, Brain Korea 21 four KNU Convergence Educational Program of Biomedical Sciences for Creative Future Talents, School of Medicine, Kyungpook National University, Daegu, 41944, South Korea.

Jae-Hong Kim (JH)

Department of Pharmacology, Brain Korea 21 four KNU Convergence Educational Program of Biomedical Sciences for Creative Future Talents, School of Medicine, Brain Science &amp; Engineering Institute, Kyungpook National University, Daegu, 41944, South Korea.

Abhinav Bhise (A)

Department of Molecular Medicine, Brain Korea 21 four KNU Convergence Educational Program of Biomedical Sciences for Creative Future Talents, School of Medicine, Kyungpook National University, Daegu, 41944, South Korea.

Hyun Park (H)

Division of Applied RI, Korea Institute of Radiological and Medical Sciences, Seoul, 01812, South Korea.

Jung Young Kim (JY)

Division of Applied RI, Korea Institute of Radiological and Medical Sciences, Seoul, 01812, South Korea.

Phuong Tu Huynh (PT)

Department of Molecular Medicine, Brain Korea 21 four KNU Convergence Educational Program of Biomedical Sciences for Creative Future Talents, School of Medicine, Kyungpook National University, Daegu, 41944, South Korea.

Subramani Rajkumar (S)

Department of Molecular Medicine, Brain Korea 21 four KNU Convergence Educational Program of Biomedical Sciences for Creative Future Talents, School of Medicine, Kyungpook National University, Daegu, 41944, South Korea.

Kiwoong Lee (K)

Department of Molecular Medicine, Brain Korea 21 four KNU Convergence Educational Program of Biomedical Sciences for Creative Future Talents, School of Medicine, Kyungpook National University, Daegu, 41944, South Korea.

Yeong Su Ha (YS)

Department of Molecular Medicine, Brain Korea 21 four KNU Convergence Educational Program of Biomedical Sciences for Creative Future Talents, School of Medicine, Kyungpook National University, Daegu, 41944, South Korea.

Seong Hwan Cho (SH)

Department of Molecular Medicine, Brain Korea 21 four KNU Convergence Educational Program of Biomedical Sciences for Creative Future Talents, School of Medicine, Kyungpook National University, Daegu, 41944, South Korea.

Jeong Eun Lim (JE)

Department of Molecular Medicine, Brain Korea 21 four KNU Convergence Educational Program of Biomedical Sciences for Creative Future Talents, School of Medicine, Kyungpook National University, Daegu, 41944, South Korea.

Kyung Won Kim (KW)

Department of Molecular Medicine, Brain Korea 21 four KNU Convergence Educational Program of Biomedical Sciences for Creative Future Talents, School of Medicine, Kyungpook National University, Daegu, 41944, South Korea.

Kyo Chul Lee (KC)

Division of Applied RI, Korea Institute of Radiological and Medical Sciences, Seoul, 01812, South Korea.

Kyoungho Suk (K)

Department of Pharmacology, Brain Korea 21 four KNU Convergence Educational Program of Biomedical Sciences for Creative Future Talents, School of Medicine, Brain Science &amp; Engineering Institute, Kyungpook National University, Daegu, 41944, South Korea.

Jeongsoo Yoo (J)

Department of Molecular Medicine, Brain Korea 21 four KNU Convergence Educational Program of Biomedical Sciences for Creative Future Talents, School of Medicine, Kyungpook National University, Daegu, 41944, South Korea. yooj@knu.ac.kr.
ORCID: 0000-0002-0752-5745

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › In vivo detection of hydrogen sulfide in the...
questionsmedicales.fr › Système nerveux › Système nerveux central › Encéphale › In vivo detection of hydrogen sulfide in the...
questionsmedicales.fr › Composés chimiques organiques › Complexes de coordination › In vivo detection of hydrogen sulfide in the...
questionsmedicales.fr › Produits chimiques inorganiques › Métaux › Métaux lourds › Cuivre › In vivo detection of hydrogen sulfide in the...
questionsmedicales.fr › Composés polycycliques › Spiranes › Fluorescéines › Fluorescéine-5-isothiocyanate › In vivo detection of hydrogen sulfide in the...
questionsmedicales.fr › Actions chimiques et utilisations › Utilisations spécialisées de produits chimiques › Produits chimiques de laboratoire › Indicateurs et réactifs › Luminescents › Colorants fluorescents › In vivo detection of hydrogen sulfide in the...
questionsmedicales.fr › Produits chimiques inorganiques › Sulfure d'hydrogène › In vivo detection of hydrogen sulfide in the...
questionsmedicales.fr › Actions chimiques et utilisations › Utilisations spécialisées de produits chimiques › Produits chimiques de laboratoire › Ligands › In vivo detection of hydrogen sulfide in the...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › In vivo detection of hydrogen sulfide in the...
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Inflammation › Maladies neuro-inflammatoires › In vivo detection of hydrogen sulfide in the...
questionsmedicales.fr › Composés chimiques organiques › Composés organométalliques › In vivo detection of hydrogen sulfide in the...
questionsmedicales.fr › Composés chimiques organiques › Composés du soufre › Thiosemicarbazones › In vivo detection of hydrogen sulfide in the...
questionsmedicales.fr › Phénomènes physiologiques › Phénomènes pharmacologiques et toxicologiques › Pharmacocinétique › Distribution tissulaire › In vivo detection of hydrogen sulfide in the...