Dually Responsive Poly(
degradable
in-vivo toxicity
poly(N-vinylcaprolactam)
polymersome
temperature-responsive
Journal
Molecules (Basel, Switzerland)
ISSN: 1420-3049
Titre abrégé: Molecules
Pays: Switzerland
ID NLM: 100964009
Informations de publication
Date de publication:
28 May 2022
28 May 2022
Historique:
received:
02
05
2022
revised:
19
05
2022
accepted:
25
05
2022
entrez:
10
6
2022
pubmed:
11
6
2022
medline:
14
6
2022
Statut:
epublish
Résumé
Limited tissue selectivity and targeting of anticancer therapeutics in systemic administration can produce harmful side effects in the body. Various polymer nano-vehicles have been developed to encapsulate therapeutics and prevent premature drug release. Dually responsive polymeric vesicles (polymersomes) assembled from temperature-/pH-sensitive block copolymers are particularly interesting for the delivery of encapsulated therapeutics to targeted tumors and inflamed tissues. We have previously demonstrated that temperature-responsive poly(
Identifiants
pubmed: 35684423
pii: molecules27113485
doi: 10.3390/molecules27113485
pmc: PMC9182360
pii:
doi:
Substances chimiques
Biocompatible Materials
0
Dimethylpolysiloxanes
0
Drug Carriers
0
Polymers
0
poly-N-vinylcaprolactam
25189-83-7
baysilon
63148-62-9
Caprolactam
6879X594Z8
Doxorubicin
80168379AG
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : National Science Foundation
ID : DMR Award 1608728
Références
J Control Release. 2007 Jul 31;120(3):131-48
pubmed: 17582642
Chem Soc Rev. 2012 Sep 21;41(18):5969-85
pubmed: 22776960
Biomaterials. 2012 Apr;33(10):2971-9
pubmed: 22244697
Int J Pharm Investig. 2015 Jul-Sep;5(3):124-33
pubmed: 26258053
J Mater Chem B. 2014 May 7;2(17):2494-2507
pubmed: 32261419
Biomacromolecules. 2017 Mar 13;18(3):649-673
pubmed: 28212005
J Control Release. 2018 Dec 28;292:163-171
pubmed: 30408555
J Am Chem Soc. 2005 Dec 28;127(51):17982-3
pubmed: 16366531
Biomacromolecules. 2020 Aug 10;21(8):3353-3363
pubmed: 32589015
Curr Pharm Des. 2012;18(23):3432-41
pubmed: 22632981
Biomacromolecules. 2019 Oct 14;20(10):3989-4000
pubmed: 31503464
Langmuir. 2006 Jun 20;22(13):5843-7
pubmed: 16768517
Soft Matter. 2016 Oct 26;12(42):8744-8754
pubmed: 27722711
Mater Sci Eng C Mater Biol Appl. 2016 Mar;60:569-578
pubmed: 26706565
ACS Biomater Sci Eng. 2019 Jan 14;5(1):70-80
pubmed: 33405869
Langmuir. 2019 Feb 5;35(5):1156-1171
pubmed: 30142975
Comb Chem High Throughput Screen. 2021 Feb 09;:
pubmed: 33568028
ACS Macro Lett. 2015 Mar 17;4(3):308-311
pubmed: 35596331
ACS Omega. 2018 Oct 31;3(10):13882-13893
pubmed: 30411053
Langmuir. 2010 Jul 6;26(13):10546-54
pubmed: 20491497
Macromol Biosci. 2020 Dec 2;:e2000259
pubmed: 33289254
Acc Chem Res. 2011 Oct 18;44(10):1039-49
pubmed: 21608994
Acta Biomater. 2020 Aug;112:190-201
pubmed: 32434076
Adv Drug Deliv Rev. 2020;157:142-160
pubmed: 32553783
Macromol Rapid Commun. 2017 Aug;38(16):
pubmed: 28605156
Nanoscale. 2021 Apr 14;13(14):6944-6952
pubmed: 33885496
Chem Soc Rev. 2017 Mar 6;46(5):1284-1294
pubmed: 28138679
Biomacromolecules. 2017 Aug 14;18(8):2552-2563
pubmed: 28700211
ACS Appl Polym Mater. 2019 Apr 12;1(4):722-736
pubmed: 31828238
Angew Chem Int Ed Engl. 2006 Sep 4;45(35):5792-5
pubmed: 16881026
J Appl Toxicol. 2007 May-Jun;27(3):262-9
pubmed: 17265417
Adv Drug Deliv Rev. 2012 Jun 15;64(9):866-84
pubmed: 22349241
Langmuir. 2012 Jan 31;28(4):2035-43
pubmed: 22149733
Biomacromolecules. 2020 May 11;21(5):1853-1864
pubmed: 32032491
Biomaterials. 2005 Jun;26(16):3055-64
pubmed: 15603800
Acta Biomater. 2018 Oct 15;80:327-340
pubmed: 30201433
ACS Appl Bio Mater. 2022 Apr 18;5(4):1670-1682
pubmed: 35294185
J Control Release. 2004 Apr 16;96(1):37-53
pubmed: 15063028
J Control Release. 2005 Feb 2;102(2):475-88
pubmed: 15653165
Gels. 2022 Apr 11;8(4):
pubmed: 35448133
Pharmaceutics. 2022 Apr 18;14(4):
pubmed: 35456717