Spontaneous splenic rupture from indeterminate dendritic cell proliferation: a case report.


Journal

Journal of surgical case reports
ISSN: 2042-8812
Titre abrégé: J Surg Case Rep
Pays: England
ID NLM: 101560169

Informations de publication

Date de publication:
Jun 2022
Historique:
received: 06 04 2022
accepted: 20 04 2022
entrez: 10 6 2022
pubmed: 11 6 2022
medline: 11 6 2022
Statut: epublish

Résumé

Spontaneous splenic rupture is a rare and life-threatening phenomenon, usually associated with an underlying infectious, inflammatory, hematological, neoplastic or rheumatologic condition. Indeterminate cell tumor is a rare neoplastic dendritic cell disorder that is poorly understood but shares immunophenotypic markers for Langerhans cells without Birbeck granules. A 73-year-old man presented with upper abdominal pain after an unwitnessed fall. Computed tomography angiography showed splenomegaly and a large ruptured splenic subcapsular hematoma. Intraoperative findings from an emergency laparotomy revealed a large hemoperitoneum and a ruptured spleen. Microscopic sections identified numerous, mostly poorly formed, small nodules classified as a proliferation of indeterminate dendritic cell tumors.

Identifiants

pubmed: 35685294
doi: 10.1093/jscr/rjac211
pii: rjac211
pmc: PMC9173739
doi:

Types de publication

Case Reports

Langues

eng

Pagination

rjac211

Informations de copyright

Published by Oxford University Press and JSCR Publishing Ltd. All rights reserved. © The Author(s) 2022.

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Auteurs

Shaikh B Iqbal (SB)

Department of Medicine, MedStar Health Internal Medicine Residency Program, Baltimore, MD, USA.

Abhinandan R Chittal (AR)

Department of Medicine, MedStar Health Internal Medicine Residency Program, Baltimore, MD, USA.

Shiavax J Rao (SJ)

Department of Medicine, MedStar Health Internal Medicine Residency Program, Baltimore, MD, USA.

Pallavi Lakra (P)

Department of Medicine, MedStar Health Internal Medicine Residency Program, Baltimore, MD, USA.

Deepty Bhansali (D)

Clinical and Laboratory Pathology, Anatomic Pathology, MedStar Health, Baltimore, MD, USA.

George Pyrgos (G)

Pulmonology and Critical Care Medicine, MedStar Franklin Square Medical Center, Baltimore, MD, USA.

Classifications MeSH