Impact of ChAdOx1 nCoV-19 (Covishield™) Vaccination: How Long Will It Persist?
Journal
International journal of microbiology
ISSN: 1687-918X
Titre abrégé: Int J Microbiol
Pays: Egypt
ID NLM: 101516125
Informations de publication
Date de publication:
2022
2022
Historique:
received:
09
12
2021
revised:
21
04
2022
accepted:
18
05
2022
entrez:
10
6
2022
pubmed:
11
6
2022
medline:
11
6
2022
Statut:
epublish
Résumé
An increase in COVID-19 immunization coverage has been linked to a decrease in the average case fatality rate. As a result, further research is needed to determine the persistence and duration of vaccine-induced protective antibodies in order to assess the effectiveness of COVID-19 vaccinations. The present study aimed to determine the COVID-19 IgG antibodies among healthcare workers (HCWs) before and after the ChAdOx1 nCoV-19 (Covishield™) vaccination. A total of 150 HCWs who had received the Covishield™ vaccine were assessed after obtaining written informed consent. Blood samples were drawn at three time points, namely, within one week prior to first dose of vaccination, prior to second dose of vaccination (28-33 days after the first dose of vaccination), and 90-95 days after the second dose of vaccination for detecting neutralizing antibodies, i.e., IgG antibodies by ELISA. The overall baseline seropositivity among the HCWs was found to be 28% (
Identifiants
pubmed: 35685779
doi: 10.1155/2022/4729844
pmc: PMC9173867
doi:
Types de publication
Journal Article
Langues
eng
Pagination
4729844Informations de copyright
Copyright © 2022 Leimapokpam Sumitra Devi et al.
Déclaration de conflit d'intérêts
The authors declare no conflicts of interest.
Références
Lancet. 2021 Jan 9;397(10269):99-111
pubmed: 33306989
Clin Infect Dis. 2021 Jan 27;72(2):301-308
pubmed: 33501951
N Engl J Med. 2021 Apr 15;384(15):1412-1423
pubmed: 33626250
BMC Med. 2021 Jun 28;19(1):155
pubmed: 34183003
Clin Microbiol Infect. 2021 Jan 20;:
pubmed: 33482352
Nat Commun. 2021 Jun 28;12(1):3991
pubmed: 34183681
N Engl J Med. 2021 Feb 4;384(5):403-416
pubmed: 33378609
BMJ. 2021 Mar 25;372:n829
pubmed: 33766927
Virus Res. 2020 Oct 15;288:198141
pubmed: 32846196
Viruses. 2021 May 26;13(6):
pubmed: 34073577
PLoS Med. 2021 Dec 10;18(12):e1003877
pubmed: 34890407
Int J Infect Dis. 2021 Jul;108:183-186
pubmed: 34022331
Nat Rev Immunol. 2021 Feb;21(2):73-82
pubmed: 33340022
Vaccine. 2021 Oct 22;39(44):6492-6509
pubmed: 34600747
Nat Commun. 2021 Feb 2;12(1):740
pubmed: 33531472
Clin Microbiol Infect. 2022 Mar;28(3):398-404
pubmed: 34838783
J Glob Health. 2021 Jul 17;11:05019
pubmed: 34326999
Nat Commun. 2021 Jul 29;12(1):4617
pubmed: 34326317
J Clin Med. 2021 Apr 01;10(7):
pubmed: 33916020
N Engl J Med. 2021 Oct 14;385(16):1474-1484
pubmed: 34320281
Diabetes Metab Syndr. 2021 May-Jun;15(3):1007-1008
pubmed: 33991805
N Engl J Med. 2020 Dec 31;383(27):2603-2615
pubmed: 33301246