Association of renal surface nodularity with arterial hypertension compared to normotensive patients.
Renal surface nodularity
hypertension
renal function
tomography
Journal
Acta radiologica (Stockholm, Sweden : 1987)
ISSN: 1600-0455
Titre abrégé: Acta Radiol
Pays: England
ID NLM: 8706123
Informations de publication
Date de publication:
Mar 2023
Mar 2023
Historique:
pubmed:
11
6
2022
medline:
22
3
2023
entrez:
10
6
2022
Statut:
ppublish
Résumé
Renal surface nodularity (RSN) is a subclinical biomarker of renal injury and may be associated with arterial hypertension. To explore the association of RSN with arterial hypertension compared to normotensive patients. A total of 205 inpatients with or without high blood pressure (HBP vs. control group) who underwent abdominal computed tomography (CT) scans were included. Their clinical characteristics included age, sex, HBP course, HBP grade, history of diabetes mellitus (DM), and renal function (estimated glomerular filtration rate [eGFR]). The HBP group included HBP/+DM and HBP/-DM based on the presence or absence of DM. The CT-based RSN grade was scored from 0 to 2 by two radiologists, respectively, where RSN grade 0 indicated smooth renal surface, grade 1 was mild RSN, and grade 2 was marked RSN. The inter-rater agreement on RSN was good (Kappa = 0.76). The age-specific rate of RSN grade 1-2 was bigger in the HBP group than in the control group (42.86% [40%-49.22%] vs. 2.18% [0.00%-22.5%]; RSN was associated with HBP compared to normotensive patients.
Sections du résumé
BACKGROUND
BACKGROUND
Renal surface nodularity (RSN) is a subclinical biomarker of renal injury and may be associated with arterial hypertension.
PURPOSE
OBJECTIVE
To explore the association of RSN with arterial hypertension compared to normotensive patients.
MATERIAL AND METHODS
METHODS
A total of 205 inpatients with or without high blood pressure (HBP vs. control group) who underwent abdominal computed tomography (CT) scans were included. Their clinical characteristics included age, sex, HBP course, HBP grade, history of diabetes mellitus (DM), and renal function (estimated glomerular filtration rate [eGFR]). The HBP group included HBP/+DM and HBP/-DM based on the presence or absence of DM. The CT-based RSN grade was scored from 0 to 2 by two radiologists, respectively, where RSN grade 0 indicated smooth renal surface, grade 1 was mild RSN, and grade 2 was marked RSN.
RESULTS
RESULTS
The inter-rater agreement on RSN was good (Kappa = 0.76). The age-specific rate of RSN grade 1-2 was bigger in the HBP group than in the control group (42.86% [40%-49.22%] vs. 2.18% [0.00%-22.5%];
CONCLUSION
CONCLUSIONS
RSN was associated with HBP compared to normotensive patients.
Identifiants
pubmed: 35686313
doi: 10.1177/02841851221106597
doi:
Substances chimiques
Biomarkers
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM