The Effect of Menopausal Status, Age, and Human Immunodeficiency Virus (HIV) on Non-AIDS Comorbidity Burden Among US Women.

Menopause may impact the earlier onset of aging-related comorbidities among women with versus without human immunodeficiency virus (HIV). We found that menopausal status, age, and HIV were independently associated with higher comorbidity burden, and that HIV impacted burden most in the pre-/perimenopausal phases.

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Déclaration de conflit d'intérêts

Potential conflicts of interest. A. A. A. reports funding for research provided to their institution from Merck and Gilead; consulting fees paid to the author from Merck and Gilead; a role as a member of the Infectious Diseases Society Board of Directors and as a member of International AIDS Society Governing Council. K. A. reports 3 grants from the National Institutes of Health (NIH) paid to their institution and unrelated to this work; support attending meetings and/or travel in the form of grants paid to their institution from the NIH. M.-C. K. reports support unrelated to this work from the NIH and paid to their institution. S. K. reports support unrelated to this work from the NIH and payment or honoraria for lectures, presentations, speakers bureaus, manuscript writing, or educational events from Integritas Communications. M. A. F. reports support unrelated to this work from the NHLBI NIH. S. N. reports payments to their institution unrelated to this work from Gilead Sciences and AbbVie Pharmaceuticals; consulting fees paid to the author from Pardes Biosciences, Theratechnologies, and Silverback Therapeutics; participation on an Advisory Board for Vir Biotechnology, a Data Safety and Monitoring Board (DSMB) for Personal Health Insights, Inc, and an Event Adjudication Committee for Bristol-Myers Squibb/PRA; and 2866 stocks with options up to 5500 from Vir Biotechnology. I. O. reports grants or contracts from Merck unrelated to this work for Study 022 and Study 024 and a $4500 payment made to the author for consulting from Accordant (a CVS Caremark Company). F. J. P. reports payment or honoraria for lectures, presentations, speakers bureaus, manuscript writing, or educational events from ViiV, Gilead, Merck, and Janssen. P. C. T. reports grants or contracts unrelated to this work and paid to their institution from Merck. T. N. T. reports the following grants unrelated to this manuscript: Public Health Solutions (PHS) 21-BHO-364 Building Equity: Intervening Together for Health (BE InTo Health) for Black and/or Hispanic/Latino Older People with HIV (ages 50 and older) (project focuses on geriatric assessments in primary HIV care; sexual health is a minor focus; author is project director) and a PRIDE Special Research Project (SRP) award (R25HL105444-09; G. Jean-Louis, Principal Investigator [PI]) Adapting Cognitive Behavioral Therapy for Menopause-Associated Insomnia (CBT-MI) for Peri- and Post-menopausal Women with HIV (adapt and tailor CBT-MI for women with HIV with complex health needs and pilot test the feasibility of implementing this intervention within a primary HIV care setting; the author is PI). T. N. T. also reports consulting fees as a Qualitative Data Consultant for Dr. Anjali Sharma at Albert Einstein College of Medicine (project focuses on older adults with HIV and sexual health is a focus). All other authors report no potential conflicts. All authors have submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Conflicts that the editors consider relevant to the content of the manuscript have been disclosed.