A review of investigated risk factors for developing equine recurrent uveitis.
ERU
genetics
horse
inflammation
ocular
predisposition
Journal
Veterinary ophthalmology
ISSN: 1463-5224
Titre abrégé: Vet Ophthalmol
Pays: England
ID NLM: 100887377
Informations de publication
Date de publication:
Mar 2023
Mar 2023
Historique:
revised:
25
04
2022
received:
03
03
2022
accepted:
27
05
2022
medline:
31
3
2023
pubmed:
13
6
2022
entrez:
12
6
2022
Statut:
ppublish
Résumé
Equine recurrent uveitis (ERU) is an ocular inflammatory disease that can be difficult to manage clinically. As such, it is the leading cause of bilateral blindness for horses. ERU is suspected to have a complex autoimmune etiology with both environmental and genetic risk factors contributing to onset and disease progression in some or all cases. Work in recent years has aimed at unraveling the primary triggers, such as infectious agents and inherited breed-specific risk factors, for disease onset, persistence, and progression. This review has aimed at encompassing those factors that have been associated, implicated, or substantiated as contributors to ERU, as well as identifying areas for which additional knowledge is needed to better understand risk for disease onset and progression. A greater understanding of the risk factors for ERU will enable earlier detection and better prognosis through prevention and new therapeutics.
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
86-100Subventions
Organisme : Morris Animal Foundation
ID : D16EQ-028
Organisme : Townsend Equine Health Research Fund
Organisme : University of California Davis, Center for Equine Health
ID : 18-17
Informations de copyright
© 2022 American College of Veterinary Ophthalmologists.
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