Goblet cell adenocarcinoma of the appendix: an update and practical approach to diagnosis and grading.
Adenocarcinoid
Appendix
Goblet cell adenocarcinoma
Goblet cell carcinoid
Pseudomyoma peritonei
Signet ring cell carcinoma
Journal
Human pathology
ISSN: 1532-8392
Titre abrégé: Hum Pathol
Pays: United States
ID NLM: 9421547
Informations de publication
Date de publication:
02 2023
02 2023
Historique:
received:
26
05
2022
accepted:
02
06
2022
pubmed:
13
6
2022
medline:
7
2
2023
entrez:
12
6
2022
Statut:
ppublish
Résumé
Goblet cell adenocarcinoma is a rare appendiceal tumour with amphicrine differentiation that has distinct morphologic and clinical features compared to carcinomas seen elsewhere in the gastrointestinal tract. These tumors have engendered considerable confusion in the literature regarding their classification, and they have been described under several different names including goblet cell carcinoid, adenocarcinoid, and adenocarcinoma, among others. In the recent fifth edition of the World Health Organization Classification of Digestive System Tumors, goblet cell adenocarcinoma is the preferred diagnosis because of the increasing recognition of a frequent co-existing high-grade adenocarcinoma component. This review will present the clinicopathologic, molecular, and immunohistochemical features of goblet cell adenocarcinoma and discuss the current challenges in diagnosis, grading, and clinical management.
Identifiants
pubmed: 35691370
pii: S0046-8177(22)00147-2
doi: 10.1016/j.humpath.2022.06.002
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
183-196Informations de copyright
Copyright © 2022. Published by Elsevier Inc.